Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
Found 153 products of "Glucocorticoid Receptor"
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Timobesone
CAS:<p>Timobesone is a topical corticosteroid.</p>Formula:C22H29FO4SPurity:98%Color and Shape:SolidMolecular weight:408.53Flumethasone pivalate
CAS:<p>Flumethasone pivalate: antipruritic, anti-inflammatory, and vasoconstrictor; for adrenocortical suppression, skin atrophy, and telangiectasia studies.</p>Formula:C27H36F2O6Purity:99.57% - 99.95%Color and Shape:SolidMolecular weight:494.57Fluticasone furoate
CAS:<p>Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.</p>Formula:C27H29F3O6SPurity:99.82%Color and Shape:SolidMolecular weight:538.58GSK9027
CAS:<p>GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.</p>Formula:C27H19F4N3O2SPurity:99.36%Color and Shape:SolidMolecular weight:525.52Demegestone
CAS:<p>Demegestone: synthetic progestogen, progesterone receptor agonist, treats luteal insufficiency, no androgenic activity.</p>Formula:C21H28O2Purity:98%Color and Shape:SolidMolecular weight:312.45Prednisolone hemisuccinate
CAS:<p>Prednisolone hemisuccinate is a soluble glucocorticoid and cortisol exerts anti-inflammatory, immunosuppressive, and antiallergic by binding to GR receptor.</p>Formula:C25H32O8Purity:99.96%Color and Shape:SolidMolecular weight:460.52Isoflupredone
CAS:<p>Isoflupredone, a synthetic corticosteroid, inhibits inflammation and immune response in animals.</p>Formula:C21H27FO5Purity:97.62% - 99.85%Color and Shape:SolidMolecular weight:378.43Paramethasone Acetate
CAS:<p>Paramethasone Acetate is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive effects that can be used in the treatment of systemic lupus</p>Formula:C24H31FO6Purity:98.1%Color and Shape:SolidMolecular weight:434.50Desisobutyryl-ciclesonide
CAS:<p>Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide with affinity for the glucocorticoid receptor. a glucocorticoid with anti-inflammatory.</p>Formula:C28H38O6Purity:98%Color and Shape:SolidMolecular weight:470.6RU 752
CAS:<p>RU 752 is an antagonist of mineralocorticoid receptor that inhibits aldosterone synthesis.</p>Formula:C22H30O4Purity:98%Color and Shape:SolidMolecular weight:358.47J9
CAS:<p>J9 is an inhibitor of Glucocorticoid resistance. J9 reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia.</p>Formula:C12H12N4Color and Shape:SolidMolecular weight:212.25Glucocorticoid receptor-IN-2
CAS:<p>Glucocorticoid receptor-IN-2 selectively targets GR with anti-inflammatory effects (IC50: 0.171 nM) and activates MMTV (EC50: 0.94 nM).</p>Formula:C25H20F4N6O2Color and Shape:SolidMolecular weight:512.46INCB13739
CAS:<p>INCB13739 is an 11β-HSD1 inhibitor that can be used in the study of hyperlipidemia and hypertriglyceridemia.</p>Formula:C28H25N3O4Purity:99.32%Color and Shape:SoildMolecular weight:467.52RU 28318, potassium salt
CAS:<p>mineralocorticoid receptor (MR) antagonist</p>Formula:C25H38KO4Purity:98%Color and Shape:SolidMolecular weight:441.67Fludrocortisone
CAS:<p>Fludrocortisone （Florinef） is a synthetic corticosteroid with moderate glucocorticoid potency and greater mineralocorticoid potency.Cost-effective and quality-assured.</p>Formula:C21H29FO5Purity:98.56% - 98.66%Color and Shape:White SolidMolecular weight:380.45(S)-Baxdrostat
CAS:<p>(S)-Baxdrostat is an S-enantiomer of Baxdrostat, which functions as an inhibitor of aldosterone synthase [1].</p>Formula:C22H25N3O2Color and Shape:SolidMolecular weight:363.45Methylprednisolone Aceponate
CAS:<p>Methylprednisolone Aceponate (SH 440), a non-halogenated corticosteroid, is a potent anti-inflammatory agent.</p>Formula:C27H36O7Purity:99.00% - 99.61%Color and Shape:SolidMolecular weight:472.57RU 25055
CAS:<p>RU 25055 is a synthetic antiglucocorticoid.</p>Formula:C24H26O2SPurity:98%Color and Shape:SolidMolecular weight:378.53PF-3882845
CAS:<p>PF-3882845, a high affinity MR antagonist (IC50=2.7 nM) for hypertension, also targets progesterone receptor (IC50: 310 nM).</p>Formula:C24H22ClN3O2Purity:99.63%Color and Shape:SolidMolecular weight:419.9RU 43044
CAS:<p>RU 43044 is a selective glucocorticoid receptor antagonist that has exhibited an antidepressant-like effect.</p>Formula:C29H34O2Purity:98%Color and Shape:SolidMolecular weight:414.58Org-34517
CAS:<p>Org-34517, a glucocorticoid receptor (GR) antagonist, is used potentially for the treatment of depression.</p>Formula:C28H30O4Purity:98%Color and Shape:SolidMolecular weight:430.54AZD2906
CAS:<p>AZD2906: selective GR agonist with human/rat IC50s - 2.2/0.3 nM (PBMC), 41.6/7.5 nM (blood); induces rat bone marrow micronuclei.</p>Formula:C26H25FN4O3Color and Shape:SolidMolecular weight:460.5Prednisolone Tebutate
CAS:<p>Prednisolone Tebutate is a synthetic glucocorticoid, and is an antiinflammatory and immunosuppressant.</p>Formula:C27H38O6Purity:98%Color and Shape:SolidMolecular weight:458.59AZD9567
CAS:<p>AZD9567: potent, selective SGRM, oral, IC50=3.8nM, effective in SCW joint inflammation.</p>Formula:C27H28F2N4O3Purity:98.4%Color and Shape:SolidMolecular weight:494.53Lorundrostat
CAS:<p>Lorundrostat is an aldosterone synthase inhibitor.</p>Formula:C24H33N7O2Purity:95.47%Color and Shape:SolidMolecular weight:451.56Glucocorticoid receptor agonist-1
CAS:<p>Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM[1].</p>Formula:C35H39NO6Purity:99.68%Color and Shape:SolidMolecular weight:569.69Dagrocorat
CAS:<p>Dagrocorat is a novel and dissociated agonist of glucocorticoid receptor.</p>Formula:C29H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:494.55HP210
CAS:<p>HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting its utility in investigating inflammation-</p>Formula:C22H19N3O2S2Purity:98%Color and Shape:SolidMolecular weight:421.54Spirorenone
CAS:<p>Spirorenone (INN) is a novel aldosterone antagonist with anti-salt corticosteroid activity, used in metabolic disease research.</p>Formula:C24H28O3Purity:98.28% - 99.84%Color and Shape:SolidMolecular weight:364.48Halobetasol
CAS:<p>Halobetasol (Ulobetasol), a corticosteroid, is utilized in the research of severe localized psoriasis [1].</p>Formula:C22H27ClF2O4Purity:98%Color and Shape:SolidMolecular weight:428.9Dexamethasone palmitate
CAS:<p>DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.</p>Formula:C38H59FO6Purity:99.28%Color and Shape:SolidMolecular weight:630.87Amebucort
CAS:<p>Amebucort is a synthetic glucocorticoid corticosteroid. It may used for the research of inflammatory disorders.</p>Formula:C28H40O7Purity:98%Color and Shape:SolidMolecular weight:488.61RU28362
CAS:<p>RU28362 is an agonist of glucocorticoid receptor.</p>Formula:C23H28O3Color and Shape:SolidMolecular weight:352.47Glucocorticoid receptor agonist
CAS:<p>Glucocorticoid receptor agonist is an effective glucocorticoid receptor agonist.</p>Formula:C20H20F4N2O2Purity:98%Color and Shape:SolidMolecular weight:396.38Glucocorticoid receptor-IN-1
CAS:<p>Glucocorticoid receptor-IN-1 selectively modulates GR with anti-inflammatory effects, represses hMMP1 (IC50: 2.11 nM), and activates MMTV (EC50: 5.59 nM).</p>Formula:C24H19F4N7O2Color and Shape:SolidMolecular weight:513.45Fosdagrocorat
CAS:<p>Fosdagrocorat is an agonist of the dissociated glucocorticoid receptor.</p>Formula:C29H30F3N2O5PColor and Shape:SolidMolecular weight:574.53Baxdrostat
CAS:<p>Baxdrostat is an aldosterone synthase inhibitor.</p>Formula:C22H25N3O2Purity:99.8%Color and Shape:SolidMolecular weight:363.45Dazucorilant
CAS:<p>Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.</p>Formula:C29H22F4N4O3SColor and Shape:SolidMolecular weight:582.57ORIC-101
CAS:<p>ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.</p>Formula:C34H47NO2Purity:98%Color and Shape:SolidMolecular weight:501.74C108297
CAS:<p>C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.</p>Formula:C30H36FN3O4SPurity:98%Color and Shape:SolidMolecular weight:553.69LEO 134310
CAS:<p>LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.</p>Formula:C34H40N2O8Color and Shape:SolidMolecular weight:604.69Glucocorticoid receptor activator 1
CAS:<p>Glucocorticoid Receptor Activator 1, a phenyl nitrogen-heterocyclic precursor, acts as an activator of the glucocorticoid receptor (GR). By activating GR, it downregulates the expression of pro-inflammatory genes stimulated by TNF, making it useful for inflammation research.</p>Formula:C11H15Cl2NO2Color and Shape:SolidMolecular weight:264.15Glucocorticoid receptor agonist-5
CAS:<p>Glucocorticoid Receptoragonist-5 (compound 4) is an effective glucocorticoid molecule acting as a potent agonist for glucocorticoid receptors. It exhibits anti-inflammatory and immunosuppressive activities and serves as an ADC cytotoxin.</p>Formula:C36H40O7Color and Shape:SolidMolecular weight:584.722-Hydroxy mifepristone
CAS:<p>22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.</p>Formula:C29H35NO3Color and Shape:SolidMolecular weight:445.59S-HP210
<p>S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.</p>Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54JTP-117968
CAS:<p>JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.</p>Formula:C31H31F3N2O2Color and Shape:SolidMolecular weight:520.59Cort108297
CAS:<p>Cort108297: selective GR modulator/antagonist, high GR affinity (Ki: 0.45nM), no other steroid receptor affinity.</p>Formula:C26H25F4N3O3SPurity:98.36% - 99.94%Color and Shape:SolidMolecular weight:535.55ZK 216348
CAS:<p>ZK 216348 also binds to Progesterone and mineralocorticoid receptors (IC50s: 20.4 nM and 79.9 nM, respectively). ZK 216348 is a nonsteroidal selective glucocorticoid receptor agonist (IC50: 20.3 nM). ZK 216348 has an anti-inflammatory activity similar to</p>Formula:C24H23F3N2O5Purity:98%Color and Shape:SolidMolecular weight:476.45Mapracorat
CAS:<p>Mapracorat (ZK-245186, BOL-303242X) is a selective glucocorticoid receptor agonist,anti-inflammatory agent for atopic dermatitis and allergic conjunctivitis.</p>Formula:C25H26F4N2O2Color and Shape:SolidMolecular weight:462.48(S)-Mapracorat
CAS:<p>(S)-Mapracorat is a selective and less active agonist of the glucocorticoid receptor.</p>Formula:C25H26F4N2O2Color and Shape:SolidMolecular weight:462.48
