Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
Found 165 products of "Glucocorticoid Receptor"
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Halobetasol propionate
CAS:Halobetasol propionate (BMY-30056) is the salt of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.
Formula:C25H31ClF2O5Purity:99.89%Color and Shape:Distributed As 0 05% OintmentMolecular weight:484.96Desoximetasone
CAS:Desoximetasone (Topicort) is a topical corticosteroid for treating skin conditions like rashes.Formula:C22H29FO4Purity:99.06% - 99.89%Color and Shape:SolidMolecular weight:376.46Corticosterone
CAS:Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.Formula:C21H30O4Purity:98.44% - ≥95%Color and Shape:SolidMolecular weight:346.46Beclometasone
CAS:Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.Formula:C22H29ClO5Purity:99.41% - 99.68%Color and Shape:White To Off-White Crystalline PowderMolecular weight:408.92Ciclesonide
CAS:Ciclesonide (Alvesco)(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.Formula:C32H44O7Purity:99.89% - >99.99%Color and Shape:SolidMolecular weight:540.69LY404039
CAS:LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).Formula:C7H9NO6SPurity:99% - 99.92%Color and Shape:SolidMolecular weight:235.22AL 082D06
CAS:AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR.Formula:C23H24ClN3O2Purity:99.05% - 99.06%Color and Shape:SolidMolecular weight:409.91Betamethasone disodium phosphate
CAS:Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) has anti-inflammatory activity and may be used in the study of rheumatoid arthritis.Formula:C22H28FNa2O8PPurity:99.37%Color and Shape:White PowderMolecular weight:516.41Triamcinolone hexacetonide
CAS:Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.Formula:C30H41FO7Purity:99.57%Color and Shape:SolidMolecular weight:532.64Hydrocortisone aceponate
CAS:Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is an effective topical glucocorticoid used in the form of a cream to treat various skinFormula:C26H36O7Purity:98.12%Color and Shape:SolidMolecular weight:460.56α-Cortolone
CAS:α-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of α-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.Formula:C21H34O5Color and Shape:SolidMolecular weight:366.49Triamcinolone acetonide-d6
CAS:Triamcinolone acetonide-d6 is a deuterated compound of Triamcinolone acetonide. Triamcinolone acetonide has a CAS number of 76-25-5. Triamcinolone acetonide is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions.Formula:C24H25D6FO6Color and Shape:SolidMolecular weight:440.53Timobesone
CAS:Timobesone is a topical corticosteroid.Formula:C22H29FO4SPurity:98%Color and Shape:SolidMolecular weight:408.53Flumethasone pivalate
CAS:Flumethasone pivalate: antipruritic, anti-inflammatory, and vasoconstrictor; for adrenocortical suppression, skin atrophy, and telangiectasia studies.Formula:C27H36F2O6Purity:99.57% - 99.95%Color and Shape:SolidMolecular weight:494.57Ref: TM-T20802
5mg60.00€10mg85.00€25mg137.00€50mg188.00€100mg269.00€200mg404.00€500mg657.00€1mL*10mM (DMSO)85.00€Fluticasone furoate
CAS:Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.Formula:C27H29F3O6SPurity:99.82%Color and Shape:SolidMolecular weight:538.58Ref: TM-T21404
5mg34.00€10mg50.00€25mg87.00€50mg130.00€100mg177.00€200mg264.00€500mg447.00€1mL*10mM (DMSO)55.00€Org-34517
CAS:Org-34517, a glucocorticoid receptor (GR) antagonist, is used potentially for the treatment of depression.Formula:C28H30O4Purity:98%Color and Shape:SolidMolecular weight:430.54Glucocorticoid receptor-IN-2
CAS:Glucocorticoid receptor-IN-2 selectively targets GR with anti-inflammatory effects (IC50: 0.171 nM) and activates MMTV (EC50: 0.94 nM).Formula:C25H20F4N6O2Color and Shape:SolidMolecular weight:512.46RU 752
CAS:RU 752 is an antagonist of mineralocorticoid receptor that inhibits aldosterone synthesis.Formula:C22H30O4Purity:98%Color and Shape:SolidMolecular weight:358.47Demegestone
CAS:Demegestone: synthetic progestogen, progesterone receptor agonist, treats luteal insufficiency, no androgenic activity.Formula:C21H28O2Purity:98%Color and Shape:SolidMolecular weight:312.45AZD2906
CAS:AZD2906: selective GR agonist with human/rat IC50s - 2.2/0.3 nM (PBMC), 41.6/7.5 nM (blood); induces rat bone marrow micronuclei.Formula:C26H25FN4O3Color and Shape:SolidMolecular weight:460.5
