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Glucocorticoid Receptor

Glucocorticoid Receptor

The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.

Found 153 products of "Glucocorticoid Receptor"

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  • Timobesone

    CAS:
    <p>Timobesone is a topical corticosteroid.</p>
    Formula:C22H29FO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:408.53
  • Flumethasone pivalate

    CAS:
    <p>Flumethasone pivalate: antipruritic, anti-inflammatory, and vasoconstrictor; for adrenocortical suppression, skin atrophy, and telangiectasia studies.</p>
    Formula:C27H36F2O6
    Purity:99.57% - 99.95%
    Color and Shape:Solid
    Molecular weight:494.57
  • Fluticasone furoate

    CAS:
    <p>Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.</p>
    Formula:C27H29F3O6S
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:538.58
  • GSK9027

    CAS:
    <p>GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.</p>
    Formula:C27H19F4N3O2S
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:525.52
  • Demegestone

    CAS:
    <p>Demegestone: synthetic progestogen, progesterone receptor agonist, treats luteal insufficiency, no androgenic activity.</p>
    Formula:C21H28O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:312.45
  • Prednisolone hemisuccinate

    CAS:
    <p>Prednisolone hemisuccinate is a soluble glucocorticoid and cortisol exerts anti-inflammatory, immunosuppressive, and antiallergic by binding to GR receptor.</p>
    Formula:C25H32O8
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:460.52
  • Isoflupredone

    CAS:
    <p>Isoflupredone, a synthetic corticosteroid, inhibits inflammation and immune response in animals.</p>
    Formula:C21H27FO5
    Purity:97.62% - 99.85%
    Color and Shape:Solid
    Molecular weight:378.43
  • Paramethasone Acetate

    CAS:
    <p>Paramethasone Acetate is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive effects that can be used in the treatment of systemic lupus</p>
    Formula:C24H31FO6
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:434.50
  • Desisobutyryl-ciclesonide

    CAS:
    <p>Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide with affinity for the glucocorticoid receptor. a glucocorticoid with anti-inflammatory.</p>
    Formula:C28H38O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:470.6
  • RU 752

    CAS:
    <p>RU 752 is an antagonist of mineralocorticoid receptor that inhibits aldosterone synthesis.</p>
    Formula:C22H30O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:358.47
  • J9

    CAS:
    <p>J9 is an inhibitor of Glucocorticoid resistance. J9 reverses Dexamethasone Resistance in T-cell Acute Lymphoblastic Leukemia.</p>
    Formula:C12H12N4
    Color and Shape:Solid
    Molecular weight:212.25
  • Glucocorticoid receptor-IN-2

    CAS:
    <p>Glucocorticoid receptor-IN-2 selectively targets GR with anti-inflammatory effects (IC50: 0.171 nM) and activates MMTV (EC50: 0.94 nM).</p>
    Formula:C25H20F4N6O2
    Color and Shape:Solid
    Molecular weight:512.46
  • INCB13739

    CAS:
    <p>INCB13739 is an 11β-HSD1 inhibitor that can be used in the study of hyperlipidemia and hypertriglyceridemia.</p>
    Formula:C28H25N3O4
    Purity:99.32%
    Color and Shape:Soild
    Molecular weight:467.52
  • RU 28318, potassium salt

    CAS:
    <p>mineralocorticoid receptor (MR) antagonist</p>
    Formula:C25H38KO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:441.67
  • Fludrocortisone

    CAS:
    <p>Fludrocortisone (Florinef) is a synthetic corticosteroid with moderate glucocorticoid potency and greater mineralocorticoid potency.Cost-effective and quality-assured.</p>
    Formula:C21H29FO5
    Purity:98.56% - 98.66%
    Color and Shape:White Solid
    Molecular weight:380.45
  • (S)-Baxdrostat

    CAS:
    <p>(S)-Baxdrostat is an S-enantiomer of Baxdrostat, which functions as an inhibitor of aldosterone synthase [1].</p>
    Formula:C22H25N3O2
    Color and Shape:Solid
    Molecular weight:363.45
  • Methylprednisolone Aceponate

    CAS:
    <p>Methylprednisolone Aceponate (SH 440), a non-halogenated corticosteroid, is a potent anti-inflammatory agent.</p>
    Formula:C27H36O7
    Purity:99.00% - 99.61%
    Color and Shape:Solid
    Molecular weight:472.57
  • RU 25055

    CAS:
    <p>RU 25055 is a synthetic antiglucocorticoid.</p>
    Formula:C24H26O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.53
  • PF-3882845

    CAS:
    <p>PF-3882845, a high affinity MR antagonist (IC50=2.7 nM) for hypertension, also targets progesterone receptor (IC50: 310 nM).</p>
    Formula:C24H22ClN3O2
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:419.9
  • RU 43044

    CAS:
    <p>RU 43044 is a selective glucocorticoid receptor antagonist that has exhibited an antidepressant-like effect.</p>
    Formula:C29H34O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.58