Androgen Receptor
The androgen receptor (AR) is a nuclear hormone receptor that is activated by binding to androgens, such as testosterone and dihydrotestosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, as well as in the regulation of several physiological processes, including muscle growth, libido, and bone density. Androgen receptor inhibitors are widely studied in the context of prostate cancer, where AR signaling is often upregulated. At CymitQuimica, we offer a range of high-quality androgen receptor modulators to support your research in endocrinology, cancer biology, and hormone regulation.
Found 207 products of "Androgen Receptor"
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BWA-6047
<p>BWA-6047 is a dual AR/AR-V7 and GSPT1 PROTAC-type degrader (AR: DC50= 3.7 nM; AR-V7: DC50= 3.0 nM; GSPT1: DC50= 1.2 nM). It facilitates the ubiquitination and degradation of AR/AR-V7 and, through molecular glue properties, induces a PPI between GSPT1 and CRBN, leading to GSPT1 degradation. BWA-6047 is applicable in prostate cancer research.</p>Formula:C42H46ClN5O7Color and Shape:SolidMolecular weight:767.308582-sec-Butylphenol
CAS:<p>2-sec-Butylphenol is an inhibitor of the androgen receptor and P450 aromatase, and can be used in research and experiments in the field of life sciences.</p>Formula:C10H14OColor and Shape:SolidMolecular weight:150.22RLA-4842
<p>RLA-4842: iron-based anti-androgen; inhibits mCRPC cell proliferation.</p>Formula:C42H46F3N5O8SColor and Shape:SolidMolecular weight:837.9Ludaterone
CAS:<p>Ludaterone is an antiandrogen agent, with potent antiandrogenic activity.</p>Formula:C20H25ClO5Color and Shape:SolidMolecular weight:380.86Gridegalutamide
CAS:<p>Gridegalutamide exhibits anti-androgen and anti-tumor activities.</p>Formula:C41H45F3N8O5SColor and Shape:SolidMolecular weight:818.91PROTAC AR-V7 degrader-1
CAS:<p>Potent, oral AR-V7 degrader (Compound 6); DC50: 0.32µM; targets AR-DBD via VHL E3; EC50: 0.88µM in 22Rv1 cells.</p>Formula:C41H52N6O6S2Color and Shape:SolidMolecular weight:789.023-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Color and Shape:Odour SolidARD-69
<p>ARD-69, a potent PROTAC, degrades AR in prostate cancer, with low DC50 values in AR+ cell lines, and suppresses AR gene expression.</p>Formula:C62H74ClFN8O7SColor and Shape:SolidMolecular weight:1129.83TD-802
CAS:<p>TD-802, an AR-targeting PROTAC with microsomal stability, shows promise for castration-resistant prostate cancer.</p>Formula:C52H61ClN10O6Color and Shape:SolidMolecular weight:957.56ARD-2051
CAS:<p>ARD-2051 is a potent, orally active proteolysis-targeting chimera degrader of the androgen receptor (AR), exhibiting DC50 values of 0.6 nM in degrading AR</p>Formula:C43H45ClN8O5Purity:98%Color and Shape:SolidMolecular weight:789.32RLA-5331
<p>RLA-5331: iron activator with anti-androgen properties; inhibits mCRPC cell proliferation.</p>Formula:C40H43F3N6O7SColor and Shape:SolidMolecular weight:808.87Inocoterone acetate
CAS:<p>Inocoterone acetate is a nonsteroidal antiandrogen that binds to the androgen receptor and possesses antiandrogenic activity in animal models.</p>Formula:C18H26O3Color and Shape:SolidMolecular weight:290.40BWA-522
<p>BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL)</p>Formula:C43H51ClN4O7Purity:98%Color and Shape:SolidMolecular weight:771.34Adrenocorticotropic hormone
CAS:<p>ACTH, a polypeptide, is secreted by the pituitary gland and regulates cortisol and androgen.</p>Color and Shape:SolidEnzalutamide-d3
CAS:<p>Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.</p>Formula:C21H16F4N4O2SColor and Shape:SolidMolecular weight:467.45Anti-Androgen receptor Antibody (8R912)
<p>Anti-Androgen receptor Antibody (8R912) is a Mouse antibody targeting Androgen receptor. Anti-Androgen receptor Antibody (8R912) can be used in ICC/IF.</p>Color and Shape:Odour LiquidAnti-Androgen receptor Antibody (7Q574)
<p>Anti-Androgen receptor Antibody (7Q574) is an antibody targeting Androgen receptor. Anti-Androgen receptor Antibody (7Q574) can be used in ELISA, WB, IHC.</p>Color and Shape:Odour Liquid(Rac)-PF-998425
CAS:<p>(Rac)-PF-998425: nonsteroidal AR antagonist, potent & selective, IC50: 26 nM (binding), 90 nM (cellular), potential for androgenetic alopecia study.</p>Formula:C14H14F3NOColor and Shape:SolidMolecular weight:269.267Anti-Androgen receptor Antibody (8H883)
<p>Anti-Androgen receptor Antibody (8H883) is an antibody targeting Androgen receptor. Anti-Androgen receptor Antibody (8H883) can be used in ELISA, IHC.</p>Color and Shape:Odour LiquidD4-abiraterone
CAS:<p>D4-abiraterone is the active metabolite of abiraterone.Δ4-Abiraterone is a inhibitor of CYP17A1, 3β-HSD and SRD5A, and an antagonist of the androgen receptor.</p>Formula:C24H29NOPurity:99.75% - 99.8%Color and Shape:SolidMolecular weight:347.49
