Tyrosinase

Tyrosinase-IN-13 (compound 3c), stemming from Flurbiprofen, acts as a potent non-competitive inhibitor of tyrosinase, exhibiting IC50 and Ki values of 68 μM and

Tyrosinase-IN-19 (compound 9), a competitive tyrosinase inhibitor, exhibits potent antioxidant activities by neutralizing ROS, ABTS+, and DPPH radicals and

Tyrosinase-IN-15 (Compound 39), with an IC50 of 7.12 μM and a Ki of 11.8 μM, functions as a tyrosinase inhibitor [1].

Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity

Potassium iodide 用于治疗过度活跃的甲状腺，并保护甲状腺免受吞咽或吸入放射性碘的辐射影响。可在意外接触放射性碘后或服用含放射性碘的药物前后使用。

Tyrosinase (Polyphenol oxidase) is a key rate-limiting enzyme encoded by the TYR gene that controls melanin production and catalyzes tyrosine oxidation.

Tyrosinase-IN-49 (Compound 12) is a potent mixed-type chalcone tyrosinase inhibitor, exhibiting an IC50 value of 0.19 μM. It demonstrates significant antioxidant potential by effectively scavenging DPPH and ABTS free radicals. The compound chelates the dinuclear copper ions at the active site of tyrosinase and reduces Cu2+ to Cu+, thereby decreasing the enzyme's catalytic activity. Tyrosinase-IN-49 has low cytotoxicity towards HEK293 cells and zebrafish embryos. Additionally, it exhibits anti-browning effects, improving food quality and serving as a potential agent in studies related to food preservation.

Tyrosinase-IN-46 (Compound III19) is a tyrosinase inhibitor with IC50 values of 3.24 nM for L-dopa and 2.79 nM for L-tyrosine. It reduces melanin synthesis, exhibiting a significant anti-pigmentation effect. Tyrosinase-IN-46 is applicable in the study of pigmentation disorders.

4-Propylresorcinol is a tyrosinase inhibitor used in skin whitening research.

Kojic acid dipalmitate (Standard) is the standard substance of Kojic acid dipalmitate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments.

Anti-Tyrosinase/TYR Antibody (7Z445) is an antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (7Z445) can be used in ELISA, IF.

2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle.

ZAP-180013 is an inhibitor of zeta-chain-associated protein kinase 70 (ZAP70,IC50 : 1.8 μM).

D-Tyrosine inhibits melanin production and biofilm formation, promoting biofilm dispersal without hindering bacterial growth.

α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.

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Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.

Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.

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Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant.