Tyrosinase
Tyrosinase is an enzyme involved in the synthesis of melanin, the pigment responsible for skin, hair, and eye color. Tyrosinase catalyzes the oxidation of tyrosine to DOPA and subsequently to DOPAquinone, which leads to melanin formation. Inhibitors of tyrosinase are of interest in the treatment of hyperpigmentation disorders, and they are also used in the cosmetic industry to reduce skin pigmentation. At CymitQuimica, we offer a wide range of high-quality tyrosinase inhibitors and reagents to support your research in dermatology, enzymology, and cosmetic science.
Found 80 products for "Tyrosinase".
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2-Ketoglutaric acid
CAS:2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle. High-Quality, Low-Cost!Formula:C5H6O5Purity:99.28% - 99.92%Color and Shape:White SolidMolecular weight:146.0981lavendustin B
CAS:Lavendustin B inhibits Tyrosine Kinase and HIV-1 integrase-LEDGF/p75 interaction.Formula:C21H19NO5Purity:95.72%Color and Shape:White SolidMolecular weight:365.38(R)-Trolox
CAS:(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Formula:C14H18O4Purity:99.88%Color and Shape:SolidMolecular weight:250.29Tyrosinase
CAS:Tyrosinase (EC 1.14.18.1) is an enzyme that oxydises phenol derivatives (e.g. tyrosine, dopamine). One unit of tyrosinase dissolved in 3mL reaction mixture will cause the absorbance at 280nm to increase by 0.001 in the presence of L-tyrosine at pH 6.5 and 25 °C. L-tyrosine is available here.Lyophilized, from mushroom. Activity ≥1000 unit/mgColor and Shape:PowderTyrosinase
CAS:Copper-containing enzyme that catalyzes the first step in the synthesis of melanin
Color and Shape:PowderTaxifolin
CAS:Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.Formula:C15H12O7Purity:94.91% - 98.9%Color and Shape:Yellowish PowderMolecular weight:304.253,4-Dihydroxybenzylamine hydrobromide
CAS:3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formula:C7H10BrNO2Purity:98.49%Color and Shape:SolidMolecular weight:220.064ER 27319 maleate
CAS:Selective inhibitor of Syk kinaseFormula:C22H24N2O5Purity:98.45%Color and Shape:Yellow SolidMolecular weight:396.44LY2457546
CAS:LY2457546 is an oral multi-target anti-angiogenic TKI inhibiting VEGFR2, PDGFR尾, FLT-3, Tie-2, Eph receptors, for leukemia and cancer research.Formula:C28H20F4N4OPurity:99.74% - 99.82%Color and Shape:White SolidMolecular weight:504.48Tyrosinase-IN-7
CAS:Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.Formula:C15H10O5Purity:99%Color and Shape:Orange SolidMolecular weight:270.24Tyrosinase-IN-2
CAS:Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.Formula:C8H8N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:224.24Tyrosinase-IN-39
Tyrosinase-IN-39 (compound 5r) is a competitive inhibitor of tyrosinase, with an IC50 of 6.4 μM, and is used in the study of skin diseases.Formula:C23H19N5O4S2Color and Shape:SolidMolecular weight:493.56Tyrosinase-IN-20
CAS:Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].Formula:C17H18N2O2SColor and Shape:SolidMolecular weight:314.4Isobutylamido thiazolyl resorcinol
CAS:Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.Formula:C13H14N2O3SColor and Shape:SolidMolecular weight:278.33Tyrosinase-IN-35
CAS:Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Formula:C17H15N5OSColor and Shape:SolidMolecular weight:337.40Plodicitinib
CAS:Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Formula:C19H22FN7O2Color and Shape:SolidMolecular weight:399.422Tyrosinase-IN-37
CAS:Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.Formula:C12H12N6SColor and Shape:SolidMolecular weight:272.33Tyrosinase-IN-33
CAS:Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.Formula:C19H17NS2Color and Shape:SolidMolecular weight:323.48Tyrosinase-IN-40
Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.Formula:C34H29N9O10Color and Shape:SolidMolecular weight:723.648Tyrosinase-IN-29
CAS:Tyrosinase-IN-29 (compound 5c) is an effective inhibitor of abTYR tyrosinase, demonstrating an IC50 value of 6.11 μM. It is suitable for further research into the inhibition of excessive skin pigmentation.Formula:C10H9NO2Color and Shape:SolidMolecular weight:175.18
