Hydroxylase
Hydroxylases are a class of enzymes that catalyze the hydroxylation of substrates, often adding hydroxyl groups (-OH) to specific positions within molecules. These enzymes are involved in a wide variety of biochemical pathways, including the synthesis of hormones, detoxification processes, and the metabolism of drugs. Hydroxylase inhibitors and activators are valuable tools in research on metabolic disorders, drug metabolism, and hormonal regulation. At CymitQuimica, we provide a selection of high-quality hydroxylase reagents to support your research in biochemistry, pharmacology, and metabolic regulation.
Found 36 products for "Hydroxylase".
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Telotristat ethyl
CAS:Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Formula:C27H26ClF3N6O3Purity:98% - 99.89%Color and Shape:White SolidMolecular weight:574.98ACT-678689
CAS:ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].Formula:C23H22ClFN6O4S2Purity:99.46%Color and Shape:SolidMolecular weight:565.04Ref: TM-T14119
1mg107.00€5mg245.00€1mL*10mM (DMSO)308.00€10mg371.00€25mg620.00€50mg858.00€100mg1,153.00€200mg1,549.00€Fenclonine
CAS:Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H10ClNO2Purity:98.81% - >99.99%Color and Shape:Crystals From Methanol White SolidMolecular weight:199.63p-Ethynylphenylalanine hydrochloride
CAS:p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Formula:C11H12ClNO2Purity:99.03% - 99.83%Color and Shape:SolidMolecular weight:225.67TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingColor and Shape:Odour SolidTPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formula:C21H18N6O4SColor and Shape:SolidMolecular weight:450.47Cuprizone
CAS:Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.Formula:C14H22N4O2Purity:99.88%Color and Shape:Yellow SolidMolecular weight:278.35GSK180
CAS:GSK180 is a potent KMO inhibitor (IC50 ~6 nM) that modulates kynurenine metabolism for metabolic, neurological, and inflammatory research.Formula:C10H7Cl2NO4Color and Shape:White SolidMolecular weight:276.07Guanoclor
CAS:Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.Formula:C9H12Cl2N4OPurity:98.79%Color and Shape:SolidMolecular weight:263.12Nepicastat hydrochloride
CAS:Nepicastat hydrochloride (RS-25560-197 hydrochloride) is a selective, orally active, dopamine-beta-hydroxylase inhibitor that crosses the blood-brain barrier.Formula:C14H15F2N3S·HClPurity:98.74% - 99.74%Color and Shape:SolidMolecular weight:331.81FG-2216
CAS:FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Formula:C12H9ClN2O4Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:280.66Tetrahydropapaverine hydrochloride
CAS:Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.Formula:C20H26ClNO4Purity:99.08%Color and Shape:SolidMolecular weight:379.878Nepicastat
CAS:Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.Formula:C14H15F2N3SColor and Shape:SolidMolecular weight:295.35Ro 61-8048
CAS:Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.Formula:C17H15N3O6S2Purity:98% - >99.99%Color and Shape:Yellow SolidMolecular weight:421.45Ref: TM-T1896
2mg37.00€5mg54.00€1mL*10mM (DMSO)60.00€10mg73.00€25mg114.00€50mg178.00€100mg284.00€200mg512.00€500mg822.00€p-Fluoro-L-phenylalanine
CAS:p-Fluoro-L-phenylalanine: TH substrate, studies enzyme regulation, binds E. coli L-leucine receptor, KD 0.26μM.Formula:C9H10FNO2Purity:99.63%Color and Shape:White SolidMolecular weight:183.18Fenclonine hydrochloride
CAS:Fenclonine hydrochloride is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formula:C9H11Cl2NO2Color and Shape:SolidMolecular weight:236.095Telotristat Etiprate
CAS:Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.Formula:C27H26ClF3N6O3·C9H9NO3Purity:99.21% - 99.83%Color and Shape:White SolidMolecular weight:754.15Ref: TM-T6044
2mg43.00€5mg63.00€1mL*10mM (DMSO)80.00€10mg96.00€25mg142.00€50mg173.00€100mg309.00€500mg740.00€Mildronate
CAS:Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitineFormula:C6H14N2O2Purity:99.94%Color and Shape:White SolidMolecular weight:146.19TETRAHYDROPIPERINE
CAS:Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.Formula:C17H23NO3Purity:98.04% - 99.61%Color and Shape:SolidMolecular weight:289.37Telotristat
CAS:Telotristat, active metabolite of LX1606, is an oral tryptophan hydroxylase inhibitor with potential antiserotonergic effects.Formula:C25H22ClF3N6O3Purity:99.70%Color and Shape:SolidMolecular weight:546.93Ref: TM-T21506
5mg46.00€1mL*10mM (DMSO)52.00€10mg62.00€25mg119.00€50mg187.00€100mg304.00€200mg424.00€Butobendine
CAS:Butobendine is a compound derived from gallic acid and exhibits significant antiarrhythmic activity.Formula:C32H48N2O10Color and Shape:SolidMolecular weight:620.73LP-533401
CAS:LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut.Formula:C27H22F4N4O3Purity:98%Color and Shape:SolidMolecular weight:526.48Phenylthiazolylthiourea
CAS:Phenylthiazolylthiourea ia a dopamine-beta-hydroxylase inhibitor.Formula:C10H9N3S2Color and Shape:SolidMolecular weight:235.33Telotristat besilate
CAS:Telotristat besilate is an inhibitor of tryptophan hydroxylase.Formula:C31H28ClF3N6O6SPurity:98%Color and Shape:SolidMolecular weight:705.11(R)-Nepicastat HCl
CAS:(R)-Nepicastat HCl (RS-25560-198 HCl), R-enantiomer, inhibits bovine/human dopamine-β-hydroxylase (IC50: 25.1/18.3 nM); not affecting other enzymes/receptors.Formula:C14H15F2N3S·HClPurity:98%Color and Shape:SolidMolecular weight:331.81Fenprinast
CAS:Fenprinast is a tryptophan-like bronchodilator utilized in the study of allergic and exercise-induced asthma. It exhibits oral activity.Formula:C16H16ClN5OColor and Shape:SolidMolecular weight:329.783-Allylphenol
CAS:3-Allylphenol is an inhibitor of dopamine β-hydroxylase (DBH; Ki = 12 mM).Formula:C9H10OColor and Shape:SolidMolecular weight:134.18JM6
CAS:JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor that acts on mouse KMO (IC50: 19.85 μM). JM6 can be used to study Alzheimer's disease.Formula:C23H26N4O6S2Color and Shape:SolidMolecular weight:518.61SU 10603
CAS:SU 10603 is a specific inhibitor of 17α-hydroxylase (also known as CYP17A1 and P450c17) used to study steroid hormone synthesis.Formula:C15H12ClNOPurity:99.93% - 99.96%Color and Shape:SolidMolecular weight:257.72EWP 815
CAS:EWP 815, a disulfiram analog, inhibits Ins(1,4)P2, Ins(1,4,5)P3 phosphatases, and dopamine β-hydroxylase.Formula:C12H22N4S4Purity:99.74%Color and Shape:SolidMolecular weight:350.59Bupicomide
CAS:Bupicomide is a dopamine β-hydroxylase inhibitor with antihypertensive and vasodilatory activity and may be used in the study of hypertension.Formula:C10H14N2OPurity:99.91% - >99.99%Color and Shape:White SolidMolecular weight:178.23Diethyl-pythiDC
CAS:Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.Formula:C14H14N2O4SPurity:99.98%Color and Shape:SolidMolecular weight:306.34LX-1031
CAS:LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.Formula:C28H25F3N4O4Purity:97.12% - 98.97%Color and Shape:White SolidMolecular weight:538.52Ref: TM-T15796
1mg52.00€5mg114.00€1mL*10mM (DMSO)136.00€10mg177.00€25mg356.00€50mg567.00€100mg888.00€200mg1,198.00€p-Ethynylphenylalanine
CAS:p-Ethynylphenylalanine (4-Ethynyl-L-phenylalanine), a tryptophan hydroxylase (TPH) inhibitor, is competitive, effective, selective, and reversible, with a Ki ofFormula:C11H11NO2Purity:99.44%Color and Shape:SolidMolecular weight:189.21GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Formula:C17H16ClN3O4Purity:98%Color and Shape:SolidMolecular weight:361.78IOX2-NH2-1
CAS:IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.Formula:C19H17N3O5Purity:98.77% - 99.91%Color and Shape:SolidMolecular weight:367.36Ref: TM-T205895
Discontinued product
