NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
Found 389 products of "NF-κB"
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ETHYL CAFFEATE
CAS:Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.Formula:C11H12O4Purity:97.79%Color and Shape:SolidMolecular weight:208.21Ref: TM-T6S1371
1mg49.00€5mg92.00€1mL*10mM (DMSO)100.00€10mg133.00€25mg259.00€50mg358.00€100mg530.00€200mg755.00€Denosumab
CAS:Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFormula:C6404H9912N1724O2004S50Purity:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Color and Shape:LiquidMolecular weight:144.71 kDaJTP 0819958 - HOIPIN-1
JTP-0819958: LUBAC inhibitor, IC50 2.8 μM; blocks NF-kB activation in vitro.Formula:C17H13NaO4Purity:99.95%Color and Shape:SolidMolecular weight:304.27Ref: TM-T8951
1mg37.00€2mg50.00€5mg65.00€1mL*10mM (DMSO)77.00€10mg95.00€25mg210.00€50mg339.00€100mg495.00€500mg1,099.00€Diethylmaleate
CAS:Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.Formula:C8H12O4Purity:98%Color and Shape:Colourless LiquidMolecular weight:172.18Chelidonic acid
CAS:Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.Formula:C7H4O6Purity:99.03%Color and Shape:SolidMolecular weight:184.10Ac2-26 acetate
Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).Formula:C141H210N32O44SPurity:98%Color and Shape:SolidMolecular weight:3089.43Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
Formula:C19H23NO4Purity:99.02% - 99.73%Color and Shape:White PowderMolecular weight:329.39ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.75%Color and Shape:SolidMolecular weight:566.51AZD3264
CAS:AZD3264 is a new type IKK2 inhibitor.Formula:C21H23N5O4SPurity:98.98% - 99.17%Color and Shape:SolidMolecular weight:441.5Ref: TM-T6771
1mg52.00€2mg70.00€5mg103.00€1mL*10mM (DMSO)114.00€10mg160.00€25mg311.00€50mg502.00€100mg805.00€500mg1,605.00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.Formula:C40H52O4Purity:95.10% - 99.79%Color and Shape:Needles From Acetone/Light Petroleum SolidMolecular weight:596.84Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 99.67%Color and Shape:SolidMolecular weight:505.56Ref: TM-TQ0131
500µg155.00€1mg187.00€5mg410.00€1mL*10mM (DMSO)449.00€10mg710.00€25mg1,381.00€50mg2,352.00€Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。Formula:C13H12Cl2O4Purity:98.61% - 99.85%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Quinoclamine
CAS:Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.Formula:C10H6ClNO2Purity:99.13% - 99.28%Color and Shape:Orange PowderMolecular weight:207.617,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purity:99.39% - 99.6%Color and Shape:SolidMolecular weight:254.24Rucaparib
CAS:Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36Ref: TM-T4463
2mg46.00€5mg70.00€1mL*10mM (DMSO)77.00€10mg109.00€25mg170.00€50mg222.00€100mg344.00€200mg512.00€500mg823.00€Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Formula:C20H34OPurity:99.17% - ≥98%Color and Shape:SolidMolecular weight:290.48Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.3614-Deoxy-11,12-didehydroandrographolide
CAS:14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.Formula:C20H28O4Purity:99.13% - 99.93%Color and Shape:SolidMolecular weight:332.43Ref: TM-TQ0185
1mg65.00€1mL*10mM (DMSO)138.00€5mg152.00€10mg215.00€25mg355.00€50mg530.00€100mg735.00€
