NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Dehydrocostus Lactone
CAS:477-43-0
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
Formula:
C15H18O2
Purity:
98.15% - 99.86%
Color and Shape:
Solid
Molecular weight:
230.3
Ref: TM-T2833
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 198.00 € | ||
| 100mg | 305.00 € | ||
| 500mg | 733.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Moslosooflavone
CAS:3570-62-5
Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.
Formula:
C17H14O5
Purity:
98% - 99.78%
Color and Shape:
Solid
Molecular weight:
298.29
Ref: TM-T5773
| 1mg | 91.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 275.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 674.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,850.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
CBL0137
CAS:1197996-80-7
CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB …
Formula:
C21H24N2O2
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
336.43
Ref: TM-T4126
| 1mg | 52.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 405.00 € | ||
| 50mg | 549.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 128.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Bay 11-7085
CAS:196309-76-9
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
Formula:
C13H15NO2S
Purity:
99.76% - 99.83%
Color and Shape:
White Solid
Molecular weight:
249.33
Ref: TM-T1934
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 193.00 € | ||
| 200mg | 250.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Ginsenoside Rg2
CAS:52286-74-5
Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as …
Formula:
C42H72O13
Purity:
99.5% - 99.77%
Color and Shape:
Solid
Molecular weight:
785.01
Ref: TM-T2873
| 2mg | 37.00 € | ||
| 5mg | 53.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 277.00 € | ||
| 500mg | 654.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Dehydrodiisoeugenol
CAS:2680-81-1
Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.
Formula:
C20H22O4
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
326.39
Ref: TM-T6S1543
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 293.00 € | ||
| 100mg | 442.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Stachydrine Hydrochloride
CAS:4136-37-2
Stachydrine Hydrochloride is an effective component that mainly extracted from the leaf of Leonurussibiricus.
Formula:
C7H14ClNO2
Purity:
99.71% - 99.92%
Color and Shape:
Light Yellow Paste
Molecular weight:
179.64
Ref: TM-T3251
| 1g | 95.00 € | ||
| 100mg | 35.00 € | ||
| 500mg | 65.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Ginsenoside Rg1
CAS:22427-39-0
Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively …
Formula:
C42H72O14
Purity:
99% - 99.74%
Color and Shape:
White Crystalline Powder
Molecular weight:
801.01
Ref: TM-T2777
| 20mg | 54.00 € | ||
| 100mg | 76.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
GSK963
CAS:2049868-46-2
GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM).
Formula:
C14H18N2O
Purity:
97.45%
Color and Shape:
Solid
Molecular weight:
230.31
Ref: TM-T5054
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 320.00 € | ||
| 200mg | 449.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
CBL0137 hydrochloride
CAS:1197397-89-9
CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates …
Formula:
C21H25ClN2O2
Purity:
98.59% - 99.35%
Color and Shape:
Solid
Molecular weight:
372.88
Ref: TM-T4361
| 1mg | 51.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 406.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 732.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Kaempferol-3-O-glucorhamnoside
CAS:40437-72-7
Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via …
Formula:
C27H30O15
Purity:
96.96% - 98.17%
Color and Shape:
Solid
Molecular weight:
594.5
Ref: TM-T5S0089
| 1mg | 50.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 328.00 € | ||
| 100mg | 477.00 € | ||
| 200mg | 657.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Saikosaponin D
CAS:20874-52-6
Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect …
Formula:
C42H68O13
Purity:
98.34% - 99.73%
Color and Shape:
White Powder
Molecular weight:
780.98
Ref: TM-T3913
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 223.00 € | ||
| 100mg | 400.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Ganoderic acid H
CAS:98665-19-1
Ganoderic acid H inhibits AP-1/NF-κB, suppressing uPA to exert antitumor effects.
Formula:
C32H44O9
Purity:
95% - 97.14%
Color and Shape:
Solid
Molecular weight:
572.69
Ref: TM-TN1664
| 1mg | 229.00 € | ||
| 5mg | 647.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
IMD-0354
CAS:978-62-1
IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.
Formula:
C15H8ClF6NO2
Purity:
99.56% - 99.71%
Color and Shape:
Solid
Molecular weight:
383.67
Ref: TM-T6141
| 2mg | 47.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 160.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 304.00 € | ||
| 500mg | 737.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Phellodendrine
CAS:6873-13-8
Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.
Formula:
C20H24NO4
Purity:
98.7% - 99.94%
Color and Shape:
Solid
Molecular weight:
342.41
Ref: TM-T6S0781
| 20mg | 106.00 € | ||
| 1mL*10mM (DMSO) | 76.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Muscone
CAS:541-91-3
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of …
Formula:
C16H30O
Purity:
99.28%
Color and Shape:
Colourless Liquid Liquid
Molecular weight:
238.41
Ref: TM-T2893
| 25mg | 46.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 138.00 € | ||
| 500mg | 221.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
IRAK4-IN-7
CAS:1801343-74-7
IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in …
Formula:
C21H19N7O3
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
417.42
Ref: TM-T5354
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 204.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 438.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Kuromanin chloride
CAS:7084-24-4
Kuromanin chloride (Chrysontemin chloride) is potent antioxidants and free radical scavengers, may act as modulators …
Formula:
C21H21ClO11
Purity:
97.27% - 98.02%
Color and Shape:
Solid
Molecular weight:
484.84
Ref: TM-T3406
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 449.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
BOT-64
CAS:113760-29-5
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's …
Formula:
C15H15NO2S
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
273.35
Ref: TM-T8705
| 1mg | 51.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
Flaconitine
CAS:77181-26-1
Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.
Formula:
C36H49NO12
Purity:
98% - 98.01%
Color and Shape:
Solid
Molecular weight:
687.77
Ref: TM-T5S1891
| 5mg | 69.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 390.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 12 Nov 2024
