NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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IRAK inhibitor 6
CAS:1042672-97-8
IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).
Formula:
C20H20N4O3S
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
396.46
Ref: TM-T5110
| 1mg | 52.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 575.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
WITHAFERIN A
CAS:5119-48-2
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory …
Formula:
C28H38O6
Purity:
97.41% - 99.83%
Color and Shape:
Solid
Molecular weight:
470.6
Ref: TM-T5687
| 1mg | 83.00 € | ||
| 5mg | 261.00 € | ||
| 10mg | 386.00 € | ||
| 25mg | 639.00 € | ||
| 50mg | 914.00 € | ||
| 100mg | 1,225.00 € | ||
| 500mg | 2,468.00 € | ||
| 1mL*10mM (DMSO) | 301.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Eclitasertib
CAS:2125450-76-0
Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).
Formula:
C19H18N6O3
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
378.38
Ref: TM-T9702
| 1mg | 107.00 € | ||
| 2mg | 150.00 € | ||
| 5mg | 228.00 € | ||
| 10mg | 360.00 € | ||
| 25mg | 654.00 € | ||
| 50mg | 907.00 € | ||
| 100mg | 1,294.00 € | ||
| 1mL*10mM (DMSO) | 251.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ginsenoside Rb3
CAS:68406-26-8
Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB …
Formula:
C53H90O22
Purity:
98% - 99.98%
Color and Shape:
Solid
Molecular weight:
1079.27
Ref: TM-T3918
| 5mg | 35.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 88.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 183.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Tizoxanide
CAS:173903-47-4
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.
Formula:
C10H7N3O4S
Purity:
100% - 99.28%
Color and Shape:
Solid
Molecular weight:
265.25
Ref: TM-T2279
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 218.00 € | ||
| 100mg | 322.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cyclo(his-pro)
CAS:53109-32-3
Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.
Formula:
C11H14N4O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
234.25
Ref: TM-T7511
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 410.00 € | ||
| 100mg | 603.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AS-2444697
CAS:1287665-60-4
AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and …
Formula:
C19H21ClN6O4
Purity:
97.43%
Color and Shape:
Solid
Molecular weight:
432.86
Ref: TM-T4299
| 1mg | 36.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 738.00 € | ||
| 200mg | 994.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Asperulosidic acid
CAS:25368-11-0
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition …
Formula:
C18H24O12
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-TN1410
| 1mg | 150.00 € | ||
| 5mg | 310.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 837.00 € | ||
| 50mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 346.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
18α-Glycyrrhetinic acid
CAS:1449-05-4
18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the …
Formula:
C30H46O4
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
470.68
Ref: TM-T2745
| 25mg | 49.00 € | ||
| 50mg | 71.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Hentriacontane
CAS:630-04-6
Hentriacontane is a natural product with various pharmacological effects including anti-inflammatory, antitumor, and antimicrobial activities.
Formula:
C31H64
Purity:
95.85%
Color and Shape:
Solid
Molecular weight:
436.84
Ref: TM-TN6963
| 100mg | 47.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Karacoline
CAS:39089-30-0
Karacolinem: natural compound, inhibits ECM breakdown in IDD through NF-κB pathway.
Formula:
C22H35NO4
Purity:
99.64% - 99.75%
Color and Shape:
Solid
Molecular weight:
377.52
Ref: TM-TN1833
| 1mg | 68.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 409.00 € | ||
| 50mg | 591.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Pristimerin
CAS:1258-84-0
Pristimerin has anticancer properties, counters hypoxia-induced cancer spread, and reduces inflammation by inhibiting ROS/IKK/NF-κB pathways.
Formula:
C30H40O4
Purity:
99.43% - 99.59%
Color and Shape:
Solid
Molecular weight:
464.64
Ref: TM-T4S1050
| 1mg | 39.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 488.00 € | ||
| 100mg | 695.00 € | ||
| 500mg | 1,420.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
OPHIOPOGONIN D
CAS:945619-74-9
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II …
Formula:
C44H70O16
Purity:
99.46% - ≥95%
Color and Shape:
Solid
Molecular weight:
855.02
Ref: TM-T5701
| 1mg | 69.00 € | ||
| 5mg | 152.00 € | ||
| 10mg | 198.00 € | ||
| 25mg | 334.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 693.00 € | ||
| 1mL*10mM (DMSO) | 180.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Flavanomarein
CAS:577-38-8
Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.
Formula:
C21H22O11
Purity:
97.53% - 98.63%
Color and Shape:
Solid
Molecular weight:
450.39
Ref: TM-TN1644
| 1mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 169.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
CAFESTOL
CAS:469-83-0
Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.
Formula:
C20H28O3
Purity:
97.06% - 99.08%
Color and Shape:
Solid
Molecular weight:
316.43
Ref: TM-T5727
| 2mg | 38.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 225.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
TOMATIDINE HYDROCHLORIDE
CAS:6192-62-7
Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not …
Formula:
C27H46ClNO2
Purity:
99.75% - ≥95%
Color and Shape:
Solid
Molecular weight:
452.11
Ref: TM-T4592
| 5mg | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Dehydrocostus Lactone
CAS:477-43-0
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.
Formula:
C15H18O2
Purity:
98.15% - 99.86%
Color and Shape:
Solid
Molecular weight:
230.3
Ref: TM-T2833
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 198.00 € | ||
| 100mg | 305.00 € | ||
| 500mg | 733.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Moslosooflavone
CAS:3570-62-5
Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.
Formula:
C17H14O5
Purity:
98% - 99.78%
Color and Shape:
Solid
Molecular weight:
298.29
Ref: TM-T5773
| 1mg | 91.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 275.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 674.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,850.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
CBL0137
CAS:1197996-80-7
CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB …
Formula:
C21H24N2O2
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
336.43
Ref: TM-T4126
| 1mg | 52.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 405.00 € | ||
| 50mg | 549.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 128.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Bay 11-7085
CAS:196309-76-9
Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).
Formula:
C13H15NO2S
Purity:
99.76% - 99.83%
Color and Shape:
White Solid
Molecular weight:
249.33
Ref: TM-T1934
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 193.00 € | ||
| 200mg | 250.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
