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NF-κB

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.

Found 445 products of "NF-κB"

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  • Metaxalone
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    Metaxalone

    CAS:
    <p>Metaxalone, sold as Skelaxin by King Pharmaceuticals, is a muscle relaxant for pain from strains and sprains.</p>
    Formula:C12H15NO3
    Purity:98.84% - 99.94%
    Color and Shape:White To Almost White Crystalline Powder Solid
    Molecular weight:221.25

    Ref: TM-T1610

  • Indacaterol maleate
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    Indacaterol maleate

    CAS:
    <p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>
    Formula:C28H32N2O7
    Purity:99.03% - 99.67%
    Color and Shape:Solid
    Molecular weight:508.56

    Ref: TM-T1239

  • Sulfasalazine
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    Sulfasalazine

    CAS:
    <p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>
    Formula:C18H14N4O5S
    Purity:98.00% - 99.28%
    Color and Shape:Minute Brownish-Yellow Crystals
    Molecular weight:398.39

    Ref: TM-T0907

  • Guaiacol
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    Guaiacol

    CAS:
    <p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>
    Formula:C7H8O2
    Purity:99.95%
    Color and Shape:Colourless To Pale Yellow Solid Crystalline
    Molecular weight:124.14

    Ref: TM-T1301

  • Urolithin B
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    Urolithin B

    CAS:
    <p>Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical</p>
    Formula:C13H8O3
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:212.2

    Ref: TM-T13265

  • Erdosteine
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    Erdosteine

    CAS:
    <p>Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.</p>
    Formula:C8H11NO4S2
    Purity:99.43% - 99.94%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:249.31

    Ref: TM-T1229

  • Theophylline monohydrate
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    Theophylline monohydrate

    CAS:
    <p>Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium</p>
    Formula:C7H8N4O2·H2O
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:198.18

    Ref: TM-T1083L

  • Aspirin
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    Aspirin

    CAS:
    <p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>
    Formula:C9H8O4
    Purity:99.78% - 99.91%
    Color and Shape:White Solid Crystalline
    Molecular weight:180.16

    Ref: TM-T0005

  • IRAK4-IN-4
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    IRAK4-IN-4

    CAS:
    <p>IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4)</p>
    Formula:C22H16N2O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:340.37

    Ref: TM-T11673

  • Dihydroartemisinin
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    Dihydroartemisinin

    CAS:
    <p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>
    Formula:C15H24O5
    Purity:98% - 99.41%
    Color and Shape:White Solid
    Molecular weight:284.35

    Ref: TM-T0607

  • Sinomenine hydrochloride
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    Sinomenine hydrochloride

    CAS:
    <p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>
    Formula:C19H24ClNO4
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:365.851

    Ref: TM-T2921

  • DMAPT
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    DMAPT

    CAS:
    <p>DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.</p>
    Formula:C17H27NO3
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:293.4

    Ref: TM-T11060

  • Lidocaine Hydrochloride hydrate
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    Lidocaine Hydrochloride hydrate

    CAS:
    <p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>
    Formula:C14H22N2O·HCl·H2O
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:288.82

    Ref: TM-T1144L

  • TBK1/IKKε-IN-2
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    TBK1/IKKε-IN-2

    CAS:
    <p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>
    Formula:C26H27N5O3
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:457.52

    Ref: TM-T15559

  • AZ1495
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    AZ1495

    CAS:
    <p>AZ1495: oral IRAK4 inhibitor (IC50: 5 nM), IRAK1 (23 nM), treats MYD88L265P DLBCL.</p>
    Formula:C21H31N5O2
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:385.5

    Ref: TM-T14367

  • Sodium salicylate
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    Sodium salicylate

    CAS:
    <p>Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.</p>
    Formula:C7H5NaO3
    Purity:99.36% - 99.92%
    Color and Shape:White Solid Amorphous
    Molecular weight:160.11

    Ref: TM-T0335

  • Baicalin
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    Baicalin

    CAS:
    <p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>
    Formula:C21H18O11
    Purity:90.08% - 99.32%
    Color and Shape:Yellow Powder
    Molecular weight:446.36

    Ref: TM-T2775

  • CDDO-dhTFEA
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    CDDO-dhTFEA

    CAS:
    <p>CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.</p>
    Formula:C33H45F3N2O3
    Purity:95.61% - 99.59%
    Color and Shape:Solid
    Molecular weight:574.72

    Ref: TM-T13604

  • Ergolide
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    Ergolide

    CAS:
    <p>Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.</p>
    Formula:C17H22O5
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:306.35

    Ref: TM-T13686

  • DCZ0415
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    DCZ0415

    CAS:
    <p>DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders DNA repair and NF-κB activity.</p>
    Formula:C23H20N2O2
    Purity:99.34% - 99.95%
    Color and Shape:Solid
    Molecular weight:356.42

    Ref: TM-T10981