NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Sinomenine hydrochloride
CAS:6080-33-7
Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.
Formula:
C19H24ClNO4
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
365.851
Ref: TM-T2921
| 50mg | 44.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 72.00 € | ||
| 500mg | 103.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Theophylline
CAS:58-55-9
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial …
Formula:
C7H8N4O2
Purity:
99.47% - 99.97%
Color and Shape:
White Solid Powder
Molecular weight:
180.16
Ref: TM-T1083
| 500mg | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Indacaterol maleate
CAS:753498-25-8
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.
Formula:
C28H32N2O7
Purity:
99.03% - 99.67%
Color and Shape:
Solid
Molecular weight:
508.56
Ref: TM-T1239
| 10mg | 36.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 74.00 € | ||
| 100mg | 100.00 € | ||
| 200mg | 149.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TBK1/IKKε-IN-2
CAS:1292310-49-6
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Formula:
C26H27N5O3
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
457.52
Ref: TM-T15559
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 476.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
NIK SMI1
CAS:1660114-31-7
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits …
Formula:
C20H19N3O4
Purity:
99.04% - 99.99%
Color and Shape:
Solid
Molecular weight:
365.38
Ref: TM-T16290
| 1mg | 158.00 € | ||
| 5mg | 384.00 € | ||
| 10mg | 578.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,243.00 € | ||
| 100mg | 1,663.00 € | ||
| 1mL*10mM (DMSO) | 430.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DCZ0415
CAS:2242470-43-3
DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders …
Formula:
C23H20N2O2
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
356.42
Ref: TM-T10981
| 1mg | 52.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 576.00 € | ||
| 100mg | 854.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Nimbolide
CAS:25990-37-8
Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.
Formula:
C27H30O7
Purity:
95.84% - 99.4%
Color and Shape:
Solid
Molecular weight:
466.52
Ref: TM-T16324
| 1mg | 87.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 792.00 € | ||
| 50mg | 1,049.00 € | ||
| 100mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 257.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MRT67307
CAS:1190378-57-4
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.
Formula:
C26H36N6O2
Purity:
99.25% - 99.79%
Color and Shape:
Solid
Molecular weight:
464.6
Ref: TM-T0097
| 1mg | 40.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 451.00 € | ||
| 100mg | 643.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ergolide
CAS:54999-07-4
Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.
Formula:
C17H22O5
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
306.35
Ref: TM-T13686
| 1mg | 73.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 238.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 721.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BAY-985
CAS:2409479-29-2
BAY-985: potent oral TBK1/IKKε inhibitor; IC50s: TBK1 (2/30 nM), IKKε (2 nM); has antitumor properties.
Formula:
C27H30F3N9O
Purity:
99.62%
Color and Shape:
Solid
Molecular weight:
553.58
Ref: TM-T10477
| 1mg | 169.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 554.00 € | ||
| 25mg | 889.00 € | ||
| 50mg | 1,198.00 € | ||
| 100mg | 1,613.00 € | ||
| 1mL*10mM (DMSO) | 428.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sulindac
CAS:38194-50-2
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.
Formula:
C20H17FO3S
Purity:
99.32% - 99.49%
Color and Shape:
Yellow Solid
Molecular weight:
356.41
Ref: TM-T0459
| 50mg | 52.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 76.00 € | ||
| 500mg | 94.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sodium salicylate
CAS:54-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and …
Formula:
C7H5NaO3
Purity:
100% - 99.98%
Color and Shape:
White Solid Amorphous
Molecular weight:
160.11
Ref: TM-T0335
| 500mg | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Asatone
CAS:38451-63-7
Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK …
Formula:
C24H32O8
Purity:
99.68% - 99.92%
Color and Shape:
Solid
Molecular weight:
448.51
Ref: TM-T10383
| 1mg | 88.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 502.00 € | ||
| 50mg | 716.00 € | ||
| 100mg | 926.00 € | ||
| 500mg | 1,839.00 € | ||
| 1mL*10mM (DMSO) | 196.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Tyloxapol
CAS:25301-02-4
Tyloxapol (Triton WR1339) is a non-ionic liquid polymer used as a surfactant.
Formula:
C70H124O13
Purity:
polymer - polymer
Color and Shape:
Clear Light Yellow Viscous Liquid
Molecular weight:
137.18
Ref: TM-T0307
| 1g | 57.00 € | ||
| 200mg | 35.00 € | ||
| 500mg | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Methylthiouracil
CAS:56-04-2
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and …
Formula:
C5H6N2OS
Purity:
100% - 99.89%
Color and Shape:
Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)
Molecular weight:
142.18
Ref: TM-T0304
| 25mg | 52.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 85.00 € | ||
| 200mg | 130.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DRI-C21045
CAS:2101765-81-3
Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).
Formula:
C32H24N2O7S
Purity:
98.10%
Color and Shape:
Solid
Molecular weight:
580.61
Ref: TM-T11096
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 487.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Theophylline monohydrate
CAS:5967-84-0
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular …
Formula:
C7H8N4O2·H2O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
198.18
Ref: TM-T1083L
| 25mg | 50.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 75.00 € | ||
| 200mg | 120.00 € | ||
| 500mg | 161.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RIPK1-IN-7
CAS:2300982-44-7
RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 …
Formula:
C25H22F3N5O2
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
481.47
Ref: TM-T12731
| 1mg | 89.00 € | ||
| 5mg | 209.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 493.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Naringin dihydrochalcone
CAS:18916-17-1
Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
Formula:
C27H34O14
Purity:
99.16%
Color and Shape:
Solid Powder
Molecular weight:
582.55
Ref: TM-T2761
| 1g | 40.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
(E/Z)-BCI
CAS:15982-84-0
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators …
Formula:
C22H23NO
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
317.42
Ref: TM-T11139
| 1mg | 78.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 435.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 817.00 € | ||
| 200mg | 1,080.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
