NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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4-Hydroxychalcone
CAS:20426-12-4
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
Formula:
C15H12O2
Purity:
100%
Color and Shape:
Yellow Powder
Molecular weight:
224.25
Ref: TM-T3005
| 100mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
RIPK1-IN-7
CAS:2300982-44-7
RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 …
Formula:
C25H22F3N5O2
Purity:
98.02%
Color and Shape:
Solid
Molecular weight:
481.47
Ref: TM-T12731
| 1mg | 89.00 € | ||
| 5mg | 209.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 493.00 € | ||
| 50mg | 682.00 € | ||
| 100mg | 909.00 € | ||
| 1mL*10mM (DMSO) | 225.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
TBK1/IKKε-IN-2
CAS:1292310-49-6
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Formula:
C26H27N5O3
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
457.52
Ref: TM-T15559
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 476.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Ergolide
CAS:54999-07-4
Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.
Formula:
C17H22O5
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
306.35
Ref: TM-T13686
| 1mg | 73.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 238.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 721.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Lidocaine Hydrochloride hydrate
CAS:6108-05-0
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
Formula:
C14H22N2O·HCl·H2O
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
288.82
Ref: TM-T1144L
| 1g | 135.00 € | ||
| 50mg | 37.00 € | ||
| 100mg | 49.00 € | ||
| 500mg | 91.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Theophylline monohydrate
CAS:5967-84-0
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular …
Formula:
C7H8N4O2·H2O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
198.18
Ref: TM-T1083L
| 25mg | 50.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 75.00 € | ||
| 200mg | 120.00 € | ||
| 500mg | 161.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
IRAK4-IN-4
CAS:1850276-58-2
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is …
Formula:
C22H16N2O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
340.37
Ref: TM-T11673
| 1mg | 62.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 785.00 € | ||
| 200mg | 1,052.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Oxaprozin
CAS:21256-18-8
Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.
Formula:
C18H15NO3
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
293.32
Ref: TM-T0708
| 25mg | 49.00 € | ||
| 50mg | 73.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 152.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
5-Aminosalicylic Acid
CAS:89-57-6
5-ASA, an anti-inflammatory salicylate, treats inflammatory bowel disease, active part of sulphalazine.
Formula:
C7H7NO3
Purity:
97.88% - 99.98%
Color and Shape:
Purplish-Tan Solid Powder
Molecular weight:
153.14
Ref: TM-T0646
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Lidocaine hydrochloride
CAS:73-78-9
Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.
Formula:
C14H23ClN2O
Purity:
100% - 99.83%
Color and Shape:
White Crystal Powder
Molecular weight:
270.798
Ref: TM-T1144
| 500mg | 54.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Aspirin
CAS:50-78-2
Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective …
Formula:
C9H8O4
Purity:
100%
Color and Shape:
White Solid Crystalline
Molecular weight:
180.16
Ref: TM-T0005
| 1g | 57.00 € | ||
| 5g | 94.00 € | ||
| 200mg | 37.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Molsidomine
CAS:25717-80-0
Molsidomine, an oral vasodilator, turns into linsidomine in the liver, releasing NO for prolonged effects.
Formula:
C9H14N4O4
Purity:
100% - 99.96%
Color and Shape:
Colorless Or White Crystalline Powder
Molecular weight:
242.23
Ref: TM-T0109
| 200mg | 35.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
(E/Z)-BCI
CAS:15982-84-0
(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators …
Formula:
C22H23NO
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
317.42
Ref: TM-T11139
| 1mg | 78.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 272.00 € | ||
| 25mg | 435.00 € | ||
| 50mg | 615.00 € | ||
| 100mg | 817.00 € | ||
| 200mg | 1,080.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Sodium salicylate
CAS:54-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and …
Formula:
C7H5NaO3
Purity:
100% - 99.98%
Color and Shape:
White Solid Amorphous
Molecular weight:
160.11
Ref: TM-T0335
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
GSK3145095
CAS:1622849-43-7
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential …
Formula:
C20H17F2N5O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
397.38
Ref: TM-T15437
| 1mg | 94.00 € | ||
| 5mg | 241.00 € | ||
| 10mg | 337.00 € | ||
| 25mg | 541.00 € | ||
| 50mg | 711.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 238.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Naringin dihydrochalcone
CAS:18916-17-1
Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.
Formula:
C27H34O14
Purity:
99.16%
Color and Shape:
Solid Powder
Molecular weight:
582.55
Ref: TM-T2761
| 1g | 40.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Asatone
CAS:38451-63-7
Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK …
Formula:
C24H32O8
Purity:
99.68% - 99.92%
Color and Shape:
Solid
Molecular weight:
448.51
Ref: TM-T10383
| 1mg | 57.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 542.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Indacaterol maleate
CAS:753498-25-8
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.
Formula:
C28H32N2O7
Purity:
99.03% - 99.67%
Color and Shape:
Solid
Molecular weight:
508.56
Ref: TM-T1239
| 10mg | 36.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 74.00 € | ||
| 100mg | 100.00 € | ||
| 200mg | 149.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
Lidocaine
CAS:137-58-6
Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil …
Formula:
C14H22N2O
Purity:
98.35% - 99.95%
Color and Shape:
Needles From Benzene Or Alcohol Solid
Molecular weight:
234.34
Ref: TM-T0468
| 500mg | 49.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
DCZ0415
CAS:2242470-43-3
DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders …
Formula:
C23H20N2O2
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
356.42
Ref: TM-T10981
| 1mg | 52.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 576.00 € | ||
| 100mg | 854.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Tuesday 5 Nov 2024
