NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Lidocaine Hydrochloride hydrate
CAS:6108-05-0
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
Formula:
C14H22N2O·HCl·H2O
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
288.82
Ref: TM-T1144L
| 1g | 135.00 € | ||
| 50mg | 37.00 € | ||
| 100mg | 49.00 € | ||
| 500mg | 91.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Baicalin
CAS:21967-41-9
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, …
Formula:
C21H18O11
Purity:
90.08% - 98.96%
Color and Shape:
Yellow Powder
Molecular weight:
446.36
Ref: TM-T2775
| 50mg | 41.00 € | ||
| 100mg | 50.00 € | ||
| 500mg | 64.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sulfasalazine
CAS:599-79-1
Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost …
Formula:
C18H14N4O5S
Purity:
98.05% - 99.28%
Color and Shape:
Minute Brownish-Yellow Crystals
Molecular weight:
398.39
Ref: TM-T0907
| 1g | 57.00 € | ||
| 500mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Urolithin B
CAS:1139-83-9
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in …
Formula:
C13H8O3
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
212.2
Ref: TM-T13265
| 10mg | 46.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 187.00 € | ||
| 500mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK3145095
CAS:1622849-43-7
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential …
Formula:
C20H17F2N5O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
397.38
Ref: TM-T15437
| 1mg | 94.00 € | ||
| 5mg | 241.00 € | ||
| 10mg | 337.00 € | ||
| 25mg | 541.00 € | ||
| 50mg | 711.00 € | ||
| 100mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 238.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
4-Hydroxychalcone
CAS:20426-12-4
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
Formula:
C15H12O2
Purity:
100%
Color and Shape:
Yellow Powder
Molecular weight:
224.25
Ref: TM-T3005
| 100mg | 48.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Aspirin
CAS:50-78-2
Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective …
Formula:
C9H8O4
Purity:
100%
Color and Shape:
White Solid Crystalline
Molecular weight:
180.16
Ref: TM-T0005
| 1g | 57.00 € | ||
| 5g | 94.00 € | ||
| 200mg | 37.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
IRAK4-IN-4
CAS:1850276-58-2
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is …
Formula:
C22H16N2O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
340.37
Ref: TM-T11673
| 1mg | 62.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 204.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 546.00 € | ||
| 100mg | 785.00 € | ||
| 200mg | 1,052.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OT-551 HCl
CAS:627085-15-8
OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used …
Formula:
C13H24ClNO3
Purity:
99.71%
Color and Shape:
Liquid
Molecular weight:
277.79
Ref: TM-T28273L
| 1mg | 182.00 € | ||
| 5mg | 400.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,267.00 € | ||
| 100mg | 1,700.00 € | ||
| 500mg | 3,415.00 € | ||
| 1mL*10mM (DMSO) | 490.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
IRAK4-IN-25
IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance …
Formula:
C23H25N5O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
435.48
Ref: TM-T79447
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
Anti-inflammatory agent 48
Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing …
Formula:
C24H21Cl2NO3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
442.33
Ref: TM-T79507
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
(−)-N-Hydroxyapiosporamide
CAS:1205676-02-3
(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both …
Formula:
C24H31NO7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
445.51
Ref: TM-T79933
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
NF-κB-IN-10
NF-κB-IN-10 (compound E1) is an inhibitor of NF-κB that mitigates heart failure symptoms through the …
Formula:
C26H30N2O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
434.53
Ref: TM-T78750
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
NF-κΒ activator 1
CAS:2387524-59-4
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
Formula:
C16H11FN2O2S
Purity:
98.85%
Color and Shape:
Solid
Molecular weight:
314.33
Ref: TM-T39965
| 1mg | 94.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 325.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 785.00 € | ||
| 100mg | 1,077.00 € | ||
| 500mg | 2,172.00 € | ||
| 1mL*10mM (DMSO) | 222.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CLEFMA
CAS:1246964-32-8
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects.
Formula:
C23H17Cl2NO4
Purity:
98.17%
Color and Shape:
Solid
Molecular weight:
442.29
Ref: TM-T9582
| 1mg | 94.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 436.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 835.00 € | ||
| 200mg | 1,089.00 € | ||
| 1mL*10mM (DMSO) | 211.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Eudebeiolide B
CAS:1934299-51-0
Eudebeiolide B, isolated from Salvia plebeia R.
Formula:
C15H18O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
262.3
Ref: TM-T79932
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
Physalin O
CAS:120849-18-5
Physalin O has anti-inflammatory properties, binds with GSH, and inhibits NO production.
Formula:
C28H32O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
528.554
Ref: TM-TN4779
| 5mg | 850.00 € | ||
| 1mL*10mM (DMSO) | 1,293.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Pratensein
CAS:2284-31-3
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 …
Formula:
C16H12O6
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
300.26
Ref: TM-TN2100
| 1mg | 180.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 638.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,375.00 € | ||
| 1mL*10mM (DMSO) | 463.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Sanggenon A
CAS:76464-71-6
Sanggenon A (Sanggenone A) exhibits anti-inflammatory properties by modulating the NF-κB and HO-1/Nrf2 signaling pathways …
Formula:
C25H24O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
436.45
Ref: TM-T79930
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
RIPK1-IN-17
RIPK1/3-IN-1 (Compound 10) is a selective inhibitor of both RIPK1 and RIPK3, effectively preventing necroptosis …
Purity:
98%
Ref: TM-T81268
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 12 Dec 2024
