NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Trovafloxacin mesylate
CAS:147059-75-4
Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
Formula:
C21H19F3N4O6S
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
512.46
Ref: TM-T13231L
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 537.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
GGTI 2147
CAS:191102-87-1
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
Formula:
C28H30N4O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
470.56
Ref: TM-T25450
| 1mg | 486.00 € | ||
| 5mg | 1,091.00 € | ||
| 10mg | 1,421.00 € | ||
| 25mg | 1,838.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 2,877.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
ALPK1-IN-3
CAS:2765633-73-4
ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances …
Formula:
C20H16F2N4OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
398.43
Ref: TM-T79790
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
RIPK1-IN-16
CAS:2561431-77-2
RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of …
Formula:
C20H19N5O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
393.46
Ref: TM-T81269
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
IRAK inhibitor 3
CAS:1012343-93-9
IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.
Formula:
C21H21N5O4S
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
439.49
Ref: TM-T11670
| 2mg | 137.00 € | ||
| 5mg | 224.00 € | ||
| 25mg | 609.00 € | ||
| 50mg | 801.00 € | ||
| 100mg | 1,198.00 € | ||
| 1mL*10mM (DMSO) | 249.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
ACHP Hydrochloride
CAS:406209-26-5
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an …
Formula:
C21H25ClN4O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
400.9
Ref: TM-T10237
| 1mg | 66.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 534.00 € | ||
| 100mg | 768.00 € | ||
| 500mg | 1,515.00 € | ||
| 1mL*10mM (DMSO) | 158.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
PROTAC IRAK4 degrader-8
CAS:2911615-06-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 …
Formula:
C43H50ClF2N11O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
874.38
Ref: TM-T79097
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
IR-Crizotinib
CAS:2387927-74-2
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) …
Formula:
C53H57Cl2FIN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1024.88
Ref: TM-T82049
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
IKK-IN-1
CAS:406211-06-1
IKK-IN-1 is an inhibitor of IKK.
Formula:
C22H26ClN3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T11633
| 25mg | 1,030.00 € | ||
| 50mg | 1,351.00 € | ||
| 100mg | 2,040.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
TBK1-IN-1
TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 …
Formula:
C27H37N7O2
Purity:
99.91%
Color and Shape:
Liquid
Molecular weight:
491.63
Ref: TM-T73322
| 1mg | 143.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
NT-0796
CAS:2272917-13-0
NT-0796 is an inflammasome NLRP3 inhibitor that inhibits NLRP3 activation.NT-0796 is a potential NDT-19795 delivery …
Formula:
C23H27N3O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
409.48
Ref: TM-T81637
| 1mg | 183.00 € | ||
| 5mg | 456.00 € | ||
| 10mg | 734.00 € | ||
| 25mg | 1,555.00 € | ||
| 50mg | 2,500.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
WEHI-345
CAS:1354825-58-3
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents …
Formula:
C22H23N7O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
401.46
Ref: TM-T3997
| 2mg | 85.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
RIPK2-IN-3
CAS:1290490-78-6
RIPK2-IN-3 (FCG806791773) is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with an IC50 value of …
Formula:
C25H22N4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
410.47
Ref: TM-T78597
| 10mg | 421.00 € | ||
| 50mg | 1,764.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
NLRP3 agonist 1
CAS:2454019-69-1
NLRP3 agonist 1 is an NLRP3 agonist that activates the enzyme Caspase-1, which promotes the …
Formula:
C15H16N6
Purity:
99.01%
Color and Shape:
Liquid
Molecular weight:
280.33
Ref: TM-T81668
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
NF-κB-IN-13
CAS:117596-92-6
NF-κB-IN-13 (compound 12) markedly suppresses LPS-induced NF-κB activation and NO synthesis in RAW264.7 macrophages, exhibiting …
Formula:
C20H20O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
340.37
Ref: TM-T79999
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
(Rac)-BAY-985
CAS:2101925-20-4
(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.
Formula:
C27H30F3N9O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
553.58
Ref: TM-T12659
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
RIPK3-IN-4
CAS:2304617-58-9
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell …
Formula:
C24H18BrFN4O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
541.39
Ref: TM-T81267
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
ADS032
CAS:2757333-37-0
ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of …
Formula:
C22H29NO4S
Purity:
99.33%
Color and Shape:
Liquid
Molecular weight:
403.54
Ref: TM-T79906
| 1mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 541.00 € | ||
| 100mg | 867.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
Ginsenoside Rk1
CAS:494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:
C42H70O12
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T4S1499
| 5mg | 91.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
IMD-biphenylC
CAS:2928463-42-5
IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.
Formula:
C35H33N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
571.67
Ref: TM-T72871
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
