NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Oditrasertib
CAS:2252271-93-3
Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in …
Formula:
C14H15F2N3O2
Purity:
98.65% - 99.65%
Color and Shape:
Solid
Molecular weight:
295.28
Ref: TM-T69726
| 1mg | 134.00 € | ||
| 5mg | 323.00 € | ||
| 10mg | 524.00 € | ||
| 25mg | 1,043.00 € | ||
| 50mg | 1,657.00 € | ||
| 100mg | 2,681.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Supercinnamaldehyde
CAS:70351-51-8
Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 …
Formula:
C12H11NO2
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
201.22
Ref: TM-T78082
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 733.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK2-IN-3
CAS:1290490-78-6
RIPK2-IN-3 (FCG806791773) is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with an IC50 value of …
Formula:
C25H22N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
410.47
Ref: TM-T78597
| 10mg | 421.00 € | ||
| 50mg | 1,764.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IRAK inhibitor 3
CAS:1012343-93-9
IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.
Formula:
C21H21N5O4S
Color and Shape:
Solid
Molecular weight:
439.49
Ref: TM-T11670
| 2mg | 137.00 € | ||
| 5mg | 224.00 € | ||
| 25mg | 609.00 € | ||
| 50mg | 801.00 € | ||
| 100mg | 1,198.00 € | ||
| 1mL*10mM (DMSO) | 249.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IRAK4-IN-28
CAS:2952532-92-0
IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a …
Formula:
C27H31N9O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
529.59
Ref: TM-T79337
| 25mg | 1,827.00 € | ||
| 50mg | 2,412.00 € | ||
| 100mg | 3,178.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IMD-vanillin
CAS:2928463-38-9
IMD-vanillin is a novel compound characterized as an imidazoquinolinone-derived dimer with NF-κB immunomodulatory properties.
Formula:
C37H45N7O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
651.8
Ref: TM-T72926
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TBK1-IN-1
TBK1-IN-1 is a TANK-binding kinase 1 inhibitor with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 …
Formula:
C27H37N7O2
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
491.63
Ref: TM-T73322
| 1mg | 143.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Trovafloxacin mesylate
CAS:147059-75-4
Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
Formula:
C21H19F3N4O6S
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
512.46
Ref: TM-T13231L
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 359.00 € | ||
| 100mg | 537.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Demethyleneberberine chloride
CAS:16705-03-6
Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by …
Formula:
C19H18ClNO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
359.8
Ref: TM-T78095
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IKK-IN-1
CAS:406211-06-1
IKK-IN-1 is an inhibitor of IKK.
Formula:
C22H26ClN3O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
431.91
Ref: TM-T11633
| 25mg | 1,030.00 € | ||
| 50mg | 1,351.00 € | ||
| 100mg | 2,040.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
WEHI-345
CAS:1354825-58-3
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents …
Formula:
C22H23N7O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
401.46
Ref: TM-T3997
| 2mg | 85.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IR-Crizotinib
CAS:2387927-74-2
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) …
Formula:
C53H57Cl2FIN7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1024.88
Ref: TM-T82049
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK1-IN-4
CAS:1481641-08-0
RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase …
Formula:
C23H23N5O2
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
401.46
Ref: TM-T12730
| 1mg | 75.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 799.00 € | ||
| 1mL*10mM (DMSO) | 148.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Dimethoxycurcumin
CAS:160096-59-3
Dimethoxycurcumin is a stable curcumin analog causing epigenetic shifts in leukemia cells, affecting gene expression.
Formula:
C23H24O6
Purity:
96.05%
Color and Shape:
Solid
Molecular weight:
396.43
Ref: TM-T19853
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 339.00 € | ||
| 200mg | 483.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GGTI 2147
CAS:191102-87-1
GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.
Formula:
C28H30N4O3
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
470.56
Ref: TM-T25450
| 1mg | 486.00 € | ||
| 5mg | 1,091.00 € | ||
| 10mg | 1,421.00 € | ||
| 25mg | 1,838.00 € | ||
| 50mg | 2,209.00 € | ||
| 100mg | 2,877.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
ACHP Hydrochloride
CAS:406209-26-5
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an …
Formula:
C21H25ClN4O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
400.9
Ref: TM-T10237
| 1mg | 43.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 313.00 € | ||
| 100mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
PROTAC IRAK4 degrader-8
CAS:2911615-06-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 …
Formula:
C43H50ClF2N11O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
874.38
Ref: TM-T79097
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
IMD-biphenylC
CAS:2928463-42-5
IMD-biphenylC: New, dual-action imidazoquinolinone dimer; inhibits tumor growth, low inflammation/toxicity.
Formula:
C35H33N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
571.67
Ref: TM-T72871
| 25mg | 1,967.00 € | ||
| 50mg | 2,598.00 € | ||
| 100mg | 3,458.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GSK840
CAS:2361146-30-5
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the …
Formula:
C21H23N3O3
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
365.43
Ref: TM-T11501
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RIPK1-IN-16
CAS:2561431-77-2
RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of …
Formula:
C20H19N5O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
393.46
Ref: TM-T81269
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 7 Jan 2025
