NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a transcription factor that regulates the expression of genes involved in immune responses, inflammation, cell survival, and proliferation. NF-κB is activated in response to various stimuli, including cytokines, pathogens, and stress signals. Dysregulation of NF-κB signaling is associated with chronic inflammatory diseases, cancer, and autoimmune disorders. At CymitQuimica, we offer a comprehensive selection of NF-κB pathway modulators to support your research in inflammation, oncology, and immune regulation.
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Goshonoside F5
CAS:90851-28-8
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both …
Formula:
C32H54O13
Purity:
98%
Color and Shape:
Solid
Molecular weight:
646.771
Ref: TM-TN4162
| 1mg | 357.00 € | ||
| 5mg | 1,756.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
INF 195
CAS:1211379-56-4
INF 195 is an inflammasome NLRP3 inhibitor that can be used to study myocardial ischemia …
Formula:
C17H22ClNO3
Color and Shape:
Soild
Molecular weight:
323.81
Ref: TM-T87945
| 5mg | 78.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 547.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cyclo(L-Pro-L-Val)
CAS:2854-40-2
Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and …
Formula:
C10H16N2O2
Purity:
98.18%
Color and Shape:
Liquid
Molecular weight:
196.25
Ref: TM-T125120
| 10mg | 46.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 132.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SN50 TFA
SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 …
Formula:
C129H230N36O29S·XCF3COOH
Color and Shape:
Liquid
Molecular weight:
2781.5 (free base)
Ref: TM-T38153
| 1mg | 303.00 € | ||
| 5mg | 1,239.00 € | ||
| 500µg | 165.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Coronalolic acid
CAS:268214-52-4
Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced …
Formula:
C30H46O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
470.68
Ref: TM-T13625
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CIB-1476
CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates …
Formula:
C28H28N2O6S
Color and Shape:
Liquid
Molecular weight:
520.6
Ref: TM-T200261
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RIPK2-IN-5
CAS:2885227-09-6
RIPK2-IN-5 is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with potential anti-inflammatory activity for the …
Formula:
C21H14N4S
Purity:
98.85%
Color and Shape:
Soild
Molecular weight:
354.43
Ref: TM-T83640
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 307.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GLPG2534
CAS:2095615-97-5
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 can …
Formula:
C21H24N6O4
Purity:
98.89% - 99.44%
Color and Shape:
Liquid
Molecular weight:
424.45
Ref: TM-T75113
| 1mg | 110.00 € | ||
| 5mg | 261.00 € | ||
| 10mg | 426.00 € | ||
| 25mg | 830.00 € | ||
| 50mg | 1,358.00 € | ||
| 100mg | 2,172.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sootepin D
CAS:1154518-97-4
Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced …
Formula:
C31H48O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
484.71
Ref: TM-T12975
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NP3-146
CAS:210826-47-4
NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of …
Formula:
C20H27ClN2O5S
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
442.96
Ref: TM-T39552
| 1mg | 368.00 € | ||
| 5mg | 911.00 € | ||
| 10mg | 1,194.00 € | ||
| 25mg | 1,805.00 € | ||
| 50mg | 2,425.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EN450
CAS:793719-01-4
EN450 is a targeted cysteine degrader of NF-κB with antiproliferative activity and potential anticancer activity …
Formula:
C11H13ClN2O3S
Purity:
99.72%
Color and Shape:
Soild
Molecular weight:
288.75
Ref: TM-T77525
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 422.00 € | ||
| 100mg | 614.00 € | ||
| 500mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Isophysalin A
CAS:1363398-67-7
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant …
Formula:
C28H30O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
526.53
Ref: TM-TN4318
| 5mg | 812.00 € | ||
| 1mL*10mM (DMSO) | 1,227.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Anti-inflammatory agent 51
CAS:2911610-03-0
Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury …
Formula:
C22H22N6O6S
Purity:
99.46%
Color and Shape:
Soild
Molecular weight:
498.51
Ref: TM-T77582
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 198.00 € | ||
| 100mg | 294.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Narasin (sodium salt)
CAS:58331-17-2
Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress …
Formula:
C43H71NaO11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
787.01
Ref: TM-T21577
| 5mg | 502.00 € | ||
| 25mg | 2,259.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BAL-0028
CAS:2842012-69-3
BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for …
Formula:
C24H22FN3O2
Purity:
99.16%
Color and Shape:
Soild
Molecular weight:
403.45
Ref: TM-T85341
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 641.00 € | ||
| 25mg | 1,000.00 € | ||
| 50mg | 1,379.00 € | ||
| 100mg | 1,823.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.
Formula:
C22H28N2O14
Purity:
98%
Color and Shape:
Solid
Molecular weight:
544.46
Ref: TM-T10318
| 5mg | 187.00 € | ||
| 10mg | 271.00 € | ||
| 50mg | 509.00 € | ||
| 100mg | 822.00 € | ||
| 200mg | To inquire | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 235.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IRAK4-IN-26
IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral …
Formula:
C22H23N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
405.45
Ref: TM-T79448
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IRAK4-IN-24
IRAK4-IN-24 (compound 16), a potent IRAK4 inhibitor, exhibits high clearance (Cl) and low oral bioavailability.
Formula:
C19H19N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
365.39
Ref: TM-T78744
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BMS986299
CAS:2242952-69-6
BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be …
Formula:
C18H19N7O
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
349.39
Ref: TM-T9572
| 1mg | 46.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 445.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Selinidin
CAS:19427-82-8
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
Formula:
C19H20O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
328.364
Ref: TM-TN4986
| 5mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 519.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
