CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
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RS102895 hydrochloride
CAS:1173022-16-6
RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).
Formula:
C21H22ClF3N2O2
Purity:
98.95%
Color and Shape:
Solid
Molecular weight:
426.86
Ref: TM-T12773
| 2mg | 47.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 313.00 € | ||
| 100mg | 473.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
J-113863
CAS:353791-85-2
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , …
Formula:
C30H37Cl2IN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
655.44
Ref: TM-T11699
| 1mg | 59.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 516.00 € | ||
| 100mg | 741.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MK-0812 Succinate
CAS:851916-42-2
MK-0812 Succinate is an effective and selective CCR2 antagonist.
Formula:
C28H40F3N3O7
Purity:
98.62%
Color and Shape:
Solid
Molecular weight:
587.63
Ref: TM-T16091
| 1mg | 64.00 € | ||
| 2mg | 92.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 525.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 179.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
CCX140
CAS:1100318-47-5
CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.
Formula:
C20H13ClF3N5O3S
Purity:
97.58% - 99.95%
Color and Shape:
Solid
Molecular weight:
495.86
Ref: TM-T14909
| 2mg | 54.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 286.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
AZ084
CAS:929300-19-6
AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It …
Formula:
C26H34N4O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
434.57
Ref: TM-T10425
| 1mg | 87.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 253.00 € | ||
| 25mg | 418.00 € | ||
| 50mg | 588.00 € | ||
| 100mg | 793.00 € | ||
| 200mg | 1,063.00 € | ||
| 1mL*10mM (DMSO) | 177.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
![CCR2-RA-[R]](https://static.cymitquimica.com/products/TM/thumb/T14900.jpg)
CCR2-RA-[R]
CAS:512177-83-2
CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).
Formula:
C18H19ClFNO3
Purity:
99.70%
Color and Shape:
Solid
Molecular weight:
351.8
Ref: TM-T14900
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 297.00 € | ||
| 100mg | 412.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
ML604086
CAS:850330-18-6
ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations.
Formula:
C27H32N4O4S
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
508.63
Ref: TM-T16111
| 1mg | 64.00 € | ||
| 5mg | 133.00 € | ||
| 10mg | 206.00 € | ||
| 25mg | 366.00 € | ||
| 50mg | 526.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Cenicriviroc Mesylate
CAS:497223-28-6
Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory …
Formula:
C42H56N4O7S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
793.05
Ref: TM-T10756
| 25mg | 408.00 € | ||
| 50mg | 688.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
MLN-3897 TFA
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 …
Formula:
C32H32ClF3N2O6
Purity:
98.62%
Color and Shape:
Liquid
Molecular weight:
633.05
Ref: TM-T28072L
| 1mg | 181.00 € | ||
| 5mg | 400.00 € | ||
| 10mg | 593.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,268.00 € | ||
| 100mg | 1,706.00 € | ||
| 500mg | 3,438.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
CCR6 inhibitor 1
CAS:2437547-04-9
CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding …
Formula:
C24H23F3N4O3S
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
504.52
Ref: TM-T10715
| 1mg | 116.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 680.00 € | ||
| 50mg | 933.00 € | ||
| 100mg | 1,300.00 € | ||
| 500mg | 2,557.00 € | ||
| 1mL*10mM (DMSO) | 312.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
CCR8 antagonist 1
CAS:723304-76-5
CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a …
Formula:
C26H29N3O5S
Purity:
97.33%
Color and Shape:
Liquid
Molecular weight:
495.59
Ref: TM-T9983
| 1mg | 51.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 604.00 € | ||
| 1mL*10mM (DMSO) | 114.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
CCR6 antagonist 1
CAS:588674-64-0
CCR6 antagonist 1 blocks CCL20/CCR6, aiding autoimmune and IBD research.
Formula:
C17H12F3NO2
Purity:
99.89%
Color and Shape:
Soild
Molecular weight:
319.28
Ref: TM-T60145
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,068.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
INCB 3284
CAS:887401-92-5
INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable …
Formula:
C26H31F3N4O4
Purity:
99.55% - 99.82%
Color and Shape:
Solid
Molecular weight:
520.54
Ref: TM-T11648
| 2mg | 39.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 275.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
7,4'-Dihydroxyflavone
CAS:2196-14-7
7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.
Formula:
C15H10O4
Purity:
99.39% - 99.6%
Color and Shape:
Solid
Molecular weight:
254.24
Ref: TM-TN1273
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 130.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Maraviroc
CAS:376348-65-1
Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s-MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.
Formula:
C29H41F2N5O
Purity:
100% - 99.55%
Color and Shape:
Brown Solid
Molecular weight:
513.67
Ref: TM-T6016
| 5mg | 51.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 267.00 € | ||
| 100mg | 480.00 € | ||
| 200mg | 620.00 € | ||
| 500mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
C-021
CAS:864289-85-0
C 021 dihydrochloride is a potent CCR4 antagonist.
Formula:
C27H41N5O2
Purity:
100.00% - 99.74%
Color and Shape:
Solid
Molecular weight:
467.65
Ref: TM-T21870
| 1mg | 51.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 299.00 € | ||
| 50mg | 463.00 € | ||
| 100mg | 648.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RE-640
CAS:140926-75-6
NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.
Formula:
C20H16Cl2N4
Purity:
99.87% - 99.91%
Color and Shape:
Solid
Molecular weight:
383.27
Ref: TM-T3188
| 5mg | 34.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 177.00 € | ||
| 200mg | 266.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Vicriviroc maleate
CAS:599179-03-0
Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency …
Formula:
C32H42F3N5O6
Purity:
97.51% - 98.16%
Color and Shape:
Solid
Molecular weight:
649.7
Ref: TM-T3435
| 1mg | 64.00 € | ||
| 5mg | 139.00 € | ||
| 10mg | 210.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 557.00 € | ||
| 100mg | 837.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD-4818
CAS:1003566-93-5
AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary …
Formula:
C27H32Cl2N2O7
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
567.46
Ref: TM-T30258
| 1mg | 45.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 289.00 € | ||
| 50mg | 434.00 € | ||
| 100mg | 649.00 € | ||
| 200mg | 876.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Vercirnon
CAS:698394-73-9
Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is …
Formula:
C22H21ClN2O4S
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
444.93
Ref: TM-T17225
| 1mg | 103.00 € | ||
| 5mg | 254.00 € | ||
| 10mg | 398.00 € | ||
| 25mg | 665.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,280.00 € | ||
| 500mg | 2,550.00 € | ||
| 1mL*10mM (DMSO) | 361.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
