CCR

AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It …

RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).

J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , …

CCX140 (CCX140-B) is an antagonist of CCR2.

ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor …

CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).

MK-0812 Succinate is an effective and selective CCR2 antagonist.

ML218 inhibits the burst activity in the subthalamic nucleus (STN) neurons. ML218 is an effective, …

CCX354 is a CCR1antagonist. It has anti-inflammatory activity.

CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).

Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory …

CCR1 antagonist 7 (compound 16r) is a chemokine receptor 1 (CCR1) antagonist, with an IC …

GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential …

CCR1 antagonist 6 (compound 16q) is a chemokine receptor 1 (CCR1) antagonist, with an IC …

CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium …

YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist. YM022 can inhibit gastrin-induced …

CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM …

CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and …

JAK-IN-3 is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 …

CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit …

MK-0812 is an effective and specific CCR2 antagonist.

AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator …

CCR2 antagonist 3 is an antagonist of CCR2.

3-Hydroxymethylcyclopentanone is a precursor to synthesize methyl epijasmonate. 3-Hydroxymethylcyclopentanone compounds, which are useful as intermediates …

BMS CCR2 22 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) …

PF-0463481 is safe and well-tolerated and has the potential for the study of diabetic nephropathy. …

GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 …

5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.

AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG …

C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and …

K777 is an orally active and irreversible inhibitor of cysteine protease with an IC50 of …

CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a …

CCR6 antagonist 1 is a CCR6 antagonist. CCR6 antagonist 1 inhibits the CCL20/CCR6 axis. CCR6 …

Eburicoic acid exhibits anti-inflammatory and antioxidant activity thereby protecting the liver from CCl4-induced hepatic damage …

Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM …

Molibresib besylate is an inhibitor of BET bromodomain (IC50: 32.5-42.5 nM).

BX471 is a potent, selective non-peptide CCR1 antagonist.

BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.

Arteether is a new, fast-acting antimalarial drug.

SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), …

Vicriviroc maleate(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The …

DAPTA(TFA) is an inhibitor of CCR5, shows potent anti-HIV activities.

Cenicriviroc is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and …

INCB8761(PF-4136309) is a specific, effective, and orally bioavailable CCR2 antagonist.

C 021 dihydrochloride is a potent CCR4 antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in …

RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and >100 …

NSC5844 (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.

TAK-779 is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 …

RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.

AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.

Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also …

4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities …

R243 is CCR8 signaling and chemotaxis inhibitor.

Maraviroc is a C-C Chemokine Receptor Type 5 (CCR5) antagonist, and for MIP-1α(IC50=3.3 nM), MIP-1β …

Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, …

INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 …

Bindarit displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.

ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; …

CCR2 antagonist 4 is a potent and specific antagonist of CCR2(IC50s of 180 nM), and …

AZD-4818 is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.