CCR
C-C chemokine receptors (CCRs) are a group of GPCRs that respond to chemokines, which are signaling molecules that guide the migration of immune cells to sites of inflammation or infection. CCRs play crucial roles in immune responses, inflammation, and the development of various diseases, including autoimmune disorders and cancer. Modulation of CCR activity is being explored as a therapeutic strategy for conditions such as rheumatoid arthritis, multiple sclerosis, and HIV infection. At CymitQuimica, we provide a range of high-quality CCR modulators to support your research in immunology, inflammation, and therapeutic development.
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Cenicriviroc
CAS:497223-25-3
Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.
Formula:
C41H52N4O4S
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
696.94
Ref: TM-TQ0297
| 1mg | 68.00 € | ||
| 2mg | 87.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 191.00 € | ||
| 25mg | 383.00 € | ||
| 50mg | 496.00 € | ||
| 100mg | 713.00 € | ||
| 200mg | 1,007.00 € | ||
| 1mL*10mM (DMSO) | 209.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD2098
CAS:566203-88-1
AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.
Formula:
C11H9Cl2N3O3S
Purity:
99.80% - 99.92%
Color and Shape:
Solid
Molecular weight:
334.18
Ref: TM-T4300
| 1mg | 35.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 531.00 € | ||
| 500mg | 1,095.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RS102895
CAS:300815-41-2
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.
Formula:
C21H21F3N2O2
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
390.4
Ref: TM-TQ0283
| 2mg | 43.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 249.00 € | ||
| 100mg | 370.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DAPTA
CAS:106362-34-9
DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.
Formula:
C35H56N10O15
Purity:
100%
Color and Shape:
Solid
Molecular weight:
856.88
Ref: TM-T7624
| 1mg | 51.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 412.00 € | ||
| 100mg | 597.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BMS-813160
CAS:1286279-29-5
BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.
Formula:
C25H40N8O2
Purity:
99.66% - 99.78%
Color and Shape:
Solid
Molecular weight:
484.64
Ref: TM-T4584
| 1mg | 62.00 € | ||
| 5mg | 135.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 560.00 € | ||
| 100mg | 799.00 € | ||
| 500mg | 1,613.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
RS 504393
CAS:300816-15-3
RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and >100 …
Formula:
C25H27N3O3
Purity:
98.49% - 98.64%
Color and Shape:
Solid
Molecular weight:
417.5
Ref: TM-T5384
| 1mg | 50.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 162.00 € | ||
| 25mg | 344.00 € | ||
| 50mg | 514.00 € | ||
| 100mg | 742.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bindarit
CAS:130641-38-2
Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.
Formula:
C19H20N2O3
Purity:
98.48% - 98.71%
Color and Shape:
Solid
Molecular weight:
324.37
Ref: TM-T6413
| 1mg | 56.00 € | ||
| 5mg | 121.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 464.00 € | ||
| 100mg | 665.00 € | ||
| 500mg | 1,356.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SB297006
CAS:58816-69-6
SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, …
Formula:
C18H18N2O5
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
342.35
Ref: TM-T4674
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 341.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BX471
CAS:217645-70-0
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.
Formula:
C21H24ClFN4O3
Purity:
98% - 99.94%
Color and Shape:
Solid
Molecular weight:
434.89
Ref: TM-T2375
| 1mg | 38.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 510.00 € | ||
| 200mg | 772.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF-4136309
CAS:1341224-83-6
PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.
Formula:
C29H31F3N6O3
Purity:
98.85% - 99.47%
Color and Shape:
Solid
Molecular weight:
568.59
Ref: TM-T3430
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 455.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ZK 756326
CAS:874911-96-3
ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 …
Formula:
C21H28N2O3
Purity:
99.06%
Color and Shape:
Solid
Molecular weight:
356.46
Ref: TM-T3360
| 2mg | 39.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 408.00 € | ||
| 200mg | 575.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
R243
CAS:688352-84-3
R243 is CCR8 signaling and chemotaxis inhibitor.
Formula:
C21H27NO4
Purity:
97.86%
Color and Shape:
Solid
Molecular weight:
357.44
Ref: TM-T24700
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 345.00 € | ||
| 100mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TAK-779
CAS:229005-80-5
TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine …
Formula:
C33H39ClN2O2
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
531.13
Ref: TM-T7499
| 1mg | 45.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 594.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CCR1 antagonist 6
CAS:2436773-01-0
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).
Formula:
C21H23ClN4O3S
Purity:
98.40% - 99.26%
Color and Shape:
Solid
Molecular weight:
446.95
Ref: TM-T10708
| 1mg | 353.00 € | ||
| 5mg | 834.00 € | ||
| 10mg | 1,110.00 € | ||
| 25mg | 1,607.00 € | ||
| 50mg | 2,025.00 € | ||
| 100mg | 2,601.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
BMS CCR2 22
CAS:445479-97-0
BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 …
Formula:
C28H34F3N5O4S
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
593.66
Ref: TM-T14688
| 1mg | 56.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 730.00 € | ||
| 200mg | 979.00 € | ||
| 1mL*10mM (DMSO) | 150.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
GSK2239633A
CAS:1240516-71-5
GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 …
Formula:
C24H25ClN4O5S2
Purity:
99.78%
Color and Shape:
Solid
Molecular weight:
549.06
Ref: TM-T11481
| 1mg | 38.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 254.00 € | ||
| 50mg | 367.00 € | ||
| 100mg | 532.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
CCX354
CAS:1010073-75-2
CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for …
Formula:
C22H22ClN7O2
Purity:
99% - 99.28%
Color and Shape:
Solid
Molecular weight:
451.91
Ref: TM-T15253
| 1mg | 247.00 € | ||
| 5mg | 555.00 € | ||
| 10mg | 898.00 € | ||
| 25mg | 1,383.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,322.00 € | ||
| 200mg | 3,122.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
BI-6901
CAS:2040401-92-9
BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 …
Formula:
C23H27N5O3S
Purity:
99.83%
Color and Shape:
Solid
Molecular weight:
453.56
Ref: TM-T36478
| 1mg | 185.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
CCR2 antagonist 3
CAS:1380100-86-6
CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.
Formula:
C17H25FN2O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
308.39
Ref: TM-T10712
| 1mg | 69.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 232.00 € | ||
| 25mg | 409.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 765.00 € | ||
| 200mg | 1,007.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
CCR4 antagonist 3-1
CAS:1957-01-3
CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with …
Formula:
C14H12N2S
Purity:
99.53%
Color and Shape:
Liquid
Molecular weight:
240.32
Ref: TM-T60336
| 1mg | 90.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 346.00 € | ||
| 25mg | 677.00 € | ||
| 50mg | 1,050.00 € | ||
| 100mg | 1,420.00 € | ||
| 500mg | 2,756.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
