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NOD

NOD

NOD proteins are intracellular receptors that recognize microbial components and play a critical role in the innate immune response by activating inflammatory signaling pathways, including NF-κB. NOD receptors are involved in the detection of bacterial infections and are associated with the pathogenesis of inflammatory bowel disease, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a variety of high-quality NOD pathway modulators to support your research in innate immunity, inflammation, and gastrointestinal health.

Found 17 products of "NOD"

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  • BAL-0028

    CAS:
    <p>BAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.</p>
    Formula:C24H22FN3O2
    Purity:99.16%
    Color and Shape:Soild
    Molecular weight:403.45
  • NP3-146

    CAS:
    <p>NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.</p>
    Formula:C20H27ClN2O5S
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:442.96
  • NT-0249

    CAS:
    <p>NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.</p>
    Formula:C22H28N5NaO4S
    Purity:98.11%
    Color and Shape:Soild
    Molecular weight:481.54
  • MCC950

    CAS:
    <p>MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!</p>
    Formula:C20H24N2O5S
    Purity:97% - 98%
    Color and Shape:Solid
    Molecular weight:404.48
  • BMS986299

    CAS:
    <p>BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.</p>
    Formula:C18H19N7O
    Purity:99.93% - 99.93%
    Color and Shape:Solid
    Molecular weight:349.39
  • LL-37 GKE acetate


    <p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial,sepsis.</p>
    Formula:C121H206N38O30
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:2673.17
  • Muramyl dipeptide

    CAS:
    <p>MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.</p>
    Formula:C19H32N4O11
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:492.48
  • NLRP3-IN-11

    CAS:
    <p>NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.</p>
    Formula:C17H17ClN4O2
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:344.8
  • AZD4144

    CAS:
    <p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>
    Formula:C18H16F3N3O3
    Purity:99.02%
    Color and Shape:Soild
    Molecular weight:379.33
  • NLRP3-IN-13

    CAS:
    <p>NLRP3-IN-13 is an NLRP3 inhibitor that inhibits NLRP3-associated inflammation.NLRP3-IN-13 can be used in the study of neurological disorders and inflammation.</p>
    Formula:C19H15N3O3S
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:365.41
  • Emlenoflast sodium

    CAS:
    <p>Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,</p>
    Formula:C19H24N4NaO3S
    Color and Shape:Solid
    Molecular weight:411.47
  • NLRP3-IN-10

    CAS:
    <p>NLRP3-IN-10 (ZVN26391) is a strong NLRP3 inhibitor, IC50 251.1 nM, that reduces IL-1β and ASC speck, hindering inflammasome activation.</p>
    Formula:C17H14BrFO3
    Purity:99.06%
    Color and Shape:Solid
    Molecular weight:365.19
  • JC124

    CAS:
    <p>JC124 is an inhibitor of NLRP3 Inflammasome and exhibits neuroprotective and anti-inflammatory activities.</p>
    Formula:C17H19ClN2O4S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:382.86
  • NLRP3-IN-9

    CAS:
    <p>NLRP3-IN-9 (INF-4E) irreversibly inhibits NLRP3 ATPase, caspase-1, and prevents pyroptosis in THP-1 cells.</p>
    Formula:C12H13ClO3
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:240.68
  • ADS032

    CAS:
    <p>ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.</p>
    Formula:C22H29NO4S
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:403.54
  • Usnoflast

    CAS:
    <p>Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.</p>
    Formula:C21H29N3O3S
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:403.54
  • NOD1/2 antagonist-1

    CAS:
    <p>NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.</p>
    Formula:C32H28ClF5N4O4
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:663.03