NOD
NOD proteins are intracellular receptors that recognize microbial components and play a critical role in the innate immune response by activating inflammatory signaling pathways, including NF-κB. NOD receptors are involved in the detection of bacterial infections and are associated with the pathogenesis of inflammatory bowel disease, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a variety of high-quality NOD pathway modulators to support your research in innate immunity, inflammation, and gastrointestinal health.
Found 28 products for "NOD".
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Dapansutrile
CAS:Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.Formula:C4H7NO2SPurity:≥98% - ≥98%Color and Shape:SolidMolecular weight:133.169Diisononyl phthalate
CAS:Controlled ProductDiisononyl phthalate (DINP), a phthalate, a plasticizer, activates the ACE/AT1R axis and inhibits NO production, inducing elevated blood pressure in mice.Formula:C26H42O4Purity:99.97%Color and Shape:Colorless Liquid In Water (Uscg 1999)Molecular weight:418.6093NP3-146
CAS:NP3-146 (NLRP3-IN-5) is an inflammasome NLRP3 inhibitor with potential anti-inflammatory activity for the study of autoimmune diseases.Formula:C20H27ClN2O5SPurity:98.97%Color and Shape:White SolidMolecular weight:442.96MCC950
CAS:MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!Formula:C20H24N2O5SPurity:97% - 99.89%Color and Shape:White SolidMolecular weight:404.48NT-0249
CAS:NT-0249 is an inflammatory vesicle NLRP3 inhibitor with anti-inflammatory activity that reverses high-fat diet-induced obesity.Formula:C22H28N5NaO4SPurity:97.26%Color and Shape:Yellow SolidMolecular weight:481.54BMS986299
CAS:BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.Formula:C18H19N7OPurity:99.93% - 99.93%Color and Shape:White SolidMolecular weight:349.39Mifamurtide
CAS:Mifamurtide (MTP-PE) is a NOD2 ligand used in macrophage activation and innate immune signaling research.Formula:C59H109N6O19PPurity:98%Color and Shape:SolidMolecular weight:1237.50LL-37 GKE acetate
LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial，sepsis.Formula:C121H206N38O30Purity:99.88%Color and Shape:SolidMolecular weight:2673.17Oxidized ATP trisodium salt
CAS:Oxidized ATP trisodium salt is an irreversible P2X7R inhibitor suppressing NLRP3 inflammasome activation.Formula:C10H11N5Na3O13P3Purity:98%Color and Shape:SolidMolecular weight:571.11Muramyl dipeptide
CAS:MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.Formula:C19H32N4O11Purity:98% - 99.34%Color and Shape:White SolidMolecular weight:492.4776NOD-IN-1
CAS:NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.Formula:C18H17NO4SPurity:99.92% - 99.93%Color and Shape:White SolidMolecular weight:343.397Nodinitib-1
CAS:Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.Formula:C14H13N3O2SPurity:99.71% - >99.99%Color and Shape:SolidMolecular weight:287.34NLRP3-IN-2
CAS:NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide.Formula:C16H17ClN2O4SPurity:98.98%Color and Shape:SolidMolecular weight:368.835INF39
CAS:INF39 is a noncytotoxic and irreversible NLRP3 inhibitor.Formula:C12H13ClO2Purity:99.5% - 99.78%Color and Shape:SolidMolecular weight:224.683CY-09
CAS:CY-09 is an NLRP3 inhibitor.Formula:C19H12F3NO3S2Purity:99.75% - >99.99%Color and Shape:SolidMolecular weight:423.43MCC950 sodium
CAS:MCC950 sodium (CP-456773 sodium) is a potent and selective inhibitor of the inflammatory vesicle NLRP3 (IC50=7.5 nM in BMDMs; IC50=8.1 nM in HMDMs).Formula:C20H23N2NaO5SPurity:95.49% - 99.80%Color and Shape:SolidMolecular weight:426.46NLRP3-IN-11
CAS:NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.Formula:C17H17ClN4O2Purity:99.99%Color and Shape:Yellow SolidMolecular weight:344.8AZD4144
CAS:AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.Formula:C18H16F3N3O3Purity:99.02%Color and Shape:Yellow SolidMolecular weight:379.33Emlenoflast sodium
CAS:Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,Formula:C19H24N4NaO3SColor and Shape:SolidMolecular weight:411.47NOD2 antagonist 1
CAS:NOD2 antagonist 1 is a selective NOD2 antagonist (IC50=5.23 μM) that suppresses MDP-induced cytokine secretion (IL-8, IL-6, TNF-α) in THP-1 and PBMCs.Formula:C26H26N4O3SPurity:98.83%Color and Shape:White SolidMolecular weight:474.57
