STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
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W1131 TFA
W1131 TFA is a potent STAT3 inhibitor inducing ferroptosis, effectively halting cancer progression in subcutaneous …
Purity:
98%
Ref: TM-T80847
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
(R)-Lisofylline
CAS:100324-81-0
(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM).
Formula:
C13H20N4O3
Purity:
99.50%
Color and Shape:
Solid
Molecular weight:
280.32
Ref: TM-T21694
| 1mg | 212.00 € | ||
| 5mg | 534.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 485.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Golotimod (TFA) (229305-39-9 free base)
Golotimod (TFA), an immunomodulating peptide, boosts antituberculosis treatments and enhances immune cell growth and macrophage …
Formula:
C18H20F3N3O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
447.36
Ref: TM-T11449L2
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Stafib-1
CAS:1688703-26-5
Stafib-1 is a selective inhibitor of STAT5β targeting SH2 domain with an IC50 of 154 …
Formula:
C26H24N2O11P2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
602.42
Ref: TM-T24838
| 2mg | 91.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Balsalazide
CAS:80573-04-2
Balsalazide (Balsalazido) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
Formula:
C17H15N3O6
Color and Shape:
Yellow To Orange Crystalline Powder
Molecular weight:
357.32
Ref: TM-T4571
| 2mg | 51.00 € | ||
| 5mg | 80.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Alantolactone
CAS:546-43-0
Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.Cost-effective …
Formula:
C15H20O2
Purity:
99.02% - 99.91%
Color and Shape:
Crystalline Powder
Molecular weight:
232.32
Ref: TM-T2896
| 5mg | 54.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 390.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Angoline
CAS:21080-31-9
Angoline hydrochloride: IL6/STAT3 inhibitor, IC50: 11.56 μM, blocks STAT3 phosphorylation and cancer cell growth.
Formula:
C22H21NO5
Purity:
97.9% - 99.96%
Color and Shape:
Solid
Molecular weight:
379.41
Ref: TM-TN6739
| 1mg | 65.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 724.00 € | ||
| 1mL*10mM (DMSO) | 157.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HODHBt
CAS:28230-32-2
HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.
Formula:
C7H5N3O2
Purity:
99.51% - 99.95%
Color and Shape:
Off-White To Yellow Solid
Molecular weight:
163.13
Ref: TM-T21267
| 100mg | 51.00 € | ||
| 200mg | 60.00 € | ||
| 500mg | 88.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Mogrol
CAS:88930-15-8
Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB …
Formula:
C30H52O4
Purity:
98.21% - 99.85%
Color and Shape:
Solid
Molecular weight:
476.73
Ref: TM-TN2346
| 1mg | 37.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 178.00 € | ||
| 50mg | 266.00 € | ||
| 100mg | 393.00 € | ||
| 500mg | 894.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Colivelin
CAS:867021-83-8
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized …
Formula:
C119H206N32O35
Purity:
96.56%
Color and Shape:
Solid
Molecular weight:
2645.1
Ref: TM-TP1856
| 1mg | 221.00 € | ||
| 5mg | 550.00 € | ||
| 10mg | 908.00 € | ||
| 25mg | 1,352.00 € | ||
| 50mg | 1,817.00 € | ||
| 100mg | 2,452.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Curculigoside
CAS:85643-19-2
1.
Formula:
C22H26O11
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
466.44
Ref: TM-T6S1966
| 1mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 333.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SC-43
CAS:1400989-25-4
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).
Formula:
C21H13ClF3N3O2
Purity:
98.44%
Color and Shape:
Solid
Molecular weight:
431.8
Ref: TM-T8478
| 1mg | 93.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 499.00 € | ||
| 50mg | 714.00 € | ||
| 100mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SH-4-54
CAS:1456632-40-8
SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.
Formula:
C29H27F5N2O5S
Purity:
98% - 99.12%
Color and Shape:
Solid
Molecular weight:
610.59
Ref: TM-T6669
| 1mg | 55.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 312.00 € | ||
| 50mg | 498.00 € | ||
| 100mg | 719.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SC99
CAS:882290-02-0
SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.
Formula:
C15H8Cl2FN3O
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
336.15
Ref: TM-T8719
| 1mg | 44.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 436.00 € | ||
| 200mg | 608.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pimozide
CAS:2062-78-4
Pimozide: antipsychotic that blocks type 2 dopamine, alpha-adrenergic, and 5-HT2 receptors, reducing tics and delusions.
Formula:
C28H29F2N3O
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
461.55
Ref: TM-T2546
| 25mg | 36.00 € | ||
| 50mg | 53.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WP1066
CAS:857064-38-1
WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in …
Formula:
C17H14BrN3O
Purity:
98.92% - 99.73%
Color and Shape:
Solid
Molecular weight:
356.22
Ref: TM-T2156
| 5mg | 52.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 293.00 € | ||
| 500mg | 714.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cucurbitacin I
CAS:2222-07-3
Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.
Formula:
C30H42O7
Purity:
96.69% - 98.2%
Color and Shape:
Solid
Molecular weight:
514.65
Ref: TM-TQ0196
| 1mg | 83.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 546.00 € | ||
| 1mL*10mM (DMSO) | 184.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RSVA405
CAS:140405-36-3
RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
Formula:
C17H20N4O2
Purity:
98.71%
Color and Shape:
Solid
Molecular weight:
312.37
Ref: TM-T8476
| 5mg | 52.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 452.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cryptotanshinone
CAS:35825-57-1
Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no …
Formula:
C19H20O3
Purity:
98% - ≥95%
Color and Shape:
Orange Needle Crystal
Molecular weight:
296.36
Ref: TM-T2814
| 10mg | 55.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 231.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Scutellarin
CAS:27740-01-8
Scutellarin from Scutellaria inhibits RANKL in osteoclasts and STAT3/Girdin/Akt in HCC cells.
Formula:
C21H18O12
Purity:
95.86% - 99.32%
Color and Shape:
Solid
Molecular weight:
462.36
Ref: TM-T2789
| 10mg | 49.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 130.00 € | ||
| 100mg | 168.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
