STAT
STAT proteins are critical components of the JAK/STAT signaling pathway, which transmits extracellular signals from cytokines and growth factors to the cell nucleus, influencing gene expression. STAT proteins are involved in regulating immune responses, cell growth, differentiation, and survival. Dysregulation of STAT signaling is implicated in various diseases, including cancer, autoimmune disorders, and chronic inflammation. At CymitQuimica, we provide a comprehensive range of STAT pathway modulators to support your research in signal transduction, immunology, and therapeutic development.
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Brevilin A
CAS:16503-32-5
Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis …
Formula:
C20H26O5
Purity:
100% - 99.74%
Color and Shape:
Solid
Molecular weight:
346.42
Ref: TM-T4672
| 1mg | 94.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 362.00 € | ||
| 25mg | 601.00 € | ||
| 50mg | 822.00 € | ||
| 100mg | 1,112.00 € | ||
| 500mg | 2,265.00 € | ||
| 1mL*10mM (DMSO) | 235.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AS2863619
CAS:2241300-51-4
AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 …
Formula:
C16H14Cl2N8O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
405.24
Ref: TM-T8378
| 1mg | 129.00 € | ||
| 2mg | 177.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 699.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,328.00 € | ||
| 1mL*10mM (DMSO) | 301.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
HO-3867
CAS:1172133-28-6
HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.
Formula:
C28H30F2N2O2
Purity:
91.18% - 99%
Color and Shape:
Solid
Molecular weight:
464.55
Ref: TM-T6537
| 1mg | 52.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 128.00 € | ||
| 25mg | 251.00 € | ||
| 50mg | 400.00 € | ||
| 100mg | 626.00 € | ||
| 200mg | 870.00 € | ||
| 1mL*10mM (DMSO) | 125.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
S3I-201
CAS:501919-59-1
S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.
Formula:
C16H15NO7S
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
365.36
Ref: TM-T2505
| 5mg | 54.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 146.00 € | ||
| 100mg | 260.00 € | ||
| 200mg | 391.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Morusin
CAS:62596-29-6
Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.
Formula:
C25H24O6
Purity:
99.72% - 99.8%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-T5S1607
| 5mg | 73.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 367.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
STAT5-IN-1
CAS:285986-31-4
STAT5-IN-1 (STAT5 Inhibitor) is a cell-permeable inhibitor which suppresses Stat5 via binding to the SH2 …
Formula:
C16H11N3O3
Purity:
99.92% - ≥95%
Color and Shape:
Solid
Molecular weight:
293.28
Ref: TM-T4216
| 5mg | 51.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 508.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Napabucasin
CAS:83280-65-3
Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.
Formula:
C14H8O4
Purity:
98.45% - 99.61%
Color and Shape:
Solid
Molecular weight:
240.21
Ref: TM-T3218
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Arnicolide D
CAS:34532-68-8
Arnicolide D is a sesquiterpene lactone.
Formula:
C19H24O5
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
332.39
Ref: TM-TN1405
| 1mg | 149.00 € | ||
| 5mg | 441.00 € | ||
| 10mg | 635.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,290.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Garcinone D
CAS:107390-08-9
Garcinone D is cytotoxic to CEM-SS cells (IC50=3.2 µg/ml), inhibits aromatase and p65 activation (IC50=3.2 …
Formula:
C24H28O7
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
428.47
Ref: TM-TN1674
| 1mg | 157.00 € | ||
| 5mg | 458.00 € | ||
| 10mg | 664.00 € | ||
| 25mg | 1,012.00 € | ||
| 50mg | 1,379.00 € | ||
| 1mL*10mM (DMSO) | 442.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Triacetylresveratrol
CAS:42206-94-0
Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic …
Formula:
C20H18O6
Purity:
99.81%
Color and Shape:
Off White Powder
Molecular weight:
354.35
Ref: TM-T5668
| 1g | 96.00 € | ||
| 500mg | 73.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Atranorin
CAS:479-20-9
Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative …
Formula:
C19H18O8
Purity:
98% - 99.57%
Color and Shape:
Solid
Molecular weight:
374.34
Ref: TM-TN1413
| 1mg | 74.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 270.00 € | ||
| 25mg | 457.00 € | ||
| 50mg | 652.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Nitidine chloride
CAS:13063-04-2
1.
Formula:
C21H18ClNO4
Purity:
96.59% - 98.91%
Color and Shape:
Solid
Molecular weight:
383.82
Ref: TM-T5S0761
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 441.00 € | ||
| 500mg | 916.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RO8191
CAS:691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Formula:
C14H5F6N5O
Purity:
98.85% - ≥98%
Color and Shape:
Solid
Molecular weight:
373.21
Ref: TM-T22142
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 478.00 € | ||
| 100mg | 698.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Balsalazide sodium hydrate
CAS:150399-21-6
Balsalazide sodium hydrate treats mild-to-moderate ulcerative colitis; higher doses enhance remission maintenance; it's safe and …
Formula:
C17H17N3Na2O8
Purity:
99.37% - 99.46%
Color and Shape:
Yellow To Orange Crystalline Powder
Molecular weight:
437.31
Ref: TM-T4615
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 227.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BP-1-102
CAS:1334493-07-0
BP-1-102 is an orally active, effective and specific STAT3 inhibitor.
Formula:
C29H27F5N2O6S
Purity:
98.61% - 99.81%
Color and Shape:
Solid
Molecular weight:
626.59
Ref: TM-T3708
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 512.00 € | ||
| 1mL*10mM (DMSO) | 104.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ML116
CAS:744270-00-6
ML116 is a potent and selective STAT3 inhibitor.
Formula:
C18H19N3S
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
309.43
Ref: TM-T8597
| 1mg | 86.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 251.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 581.00 € | ||
| 100mg | 786.00 € | ||
| 200mg | 1,042.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Picroside I
CAS:27409-30-9
Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis …
Formula:
C24H28O11
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
492.47
Ref: TM-T2787
| 20mg | 54.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SH5-07
CAS:1456632-41-9
SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
Formula:
C29H28F5N3O5S
Purity:
95.54%
Color and Shape:
Solid
Molecular weight:
625.61
Ref: TM-TQ0052
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 192.00 € | ||
| 50mg | 285.00 € | ||
| 100mg | 414.00 € | ||
| 200mg | 584.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
FLLL32
CAS:1226895-15-3
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
Formula:
C28H32O6
Purity:
96.39% - 99.8%
Color and Shape:
Solid
Molecular weight:
464.55
Ref: TM-T6838
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 343.00 € | ||
| 500mg | 822.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
2-(1,8-naphthyridin-2-yl)phenol
CAS:65182-56-1
2-NP is a STAT1 enhancer.
Formula:
C14H10N2O
Purity:
99.33% - 99.82%
Color and Shape:
Solid
Molecular weight:
222.24
Ref: TM-T2168
| 5mg | 59.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 458.00 € | ||
| 200mg | 667.00 € | ||
| 500mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
