MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 892 products of "MAPK"
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RAS inhibitor Abd-7
CAS:Abd-7: potent RAS inhibitor (Kd=51 nM) that blocks RAS-effector PPI, disrupting KRAS, NRAS Q61H, HRAS G12V signaling.Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46RAF-IN-1
CAS:RAF-IN-1: strong b/cRAF inhibitor; cRAF IC50=3.8 nM; bRAFwt IC50=36 nM; bRAFV600E IC50=29.4 nM; A375/H358 bRAFV600E GI50=3.4/2.9 nM.Formula:C26H22F3N3O4Color and Shape:SolidMolecular weight:497.47KRAS inhibitor-4
CAS:KRAS inhibitor-4 developed as anticancer agents, is a potent KRAS inhibitor.Formula:C30H39ClN8OPurity:98%Color and Shape:SolidMolecular weight:563.14Anti-inflammatory agent 33
CAS:Agent 33: potent p38α inhibitor, reduces NO, iNOS, COX-2, p-p38α, p-MK2; shows anti-inflammatory effects.Formula:C22H15N3O5SColor and Shape:SolidMolecular weight:433.44RSK2-IN-3
CAS:RSK2-IN-3 (Compound 26) is a covalent, reversible inhibitor of RPS6KA3 (RSK2) kinase.Formula:C24H26N4O5Color and Shape:SolidMolecular weight:450.49MLKL-IN-5
CAS:MLKL-IN-5 is a potent MLKL inhibitor that mediates necroptosis .Formula:C18H20N6O4SColor and Shape:SolidMolecular weight:416.45HPK1-IN-28
CAS:HPK1-IN-28 inhibits HPK1, boosts anti-tumor immunity, and shows promise in immune disease research per patent WO2021175270A1.Formula:C25H22F3N5O4Color and Shape:SolidMolecular weight:513.47JTP-70902
CAS:JTP-70902 is a protein kinase inhibitor with antineoplastic activity.Formula:C24H21BrFN5O5SColor and Shape:SolidMolecular weight:590.42BRAF V600E/CRAF-IN-1
CAS:BRAF V600E/CRAF-IN-1: potent BRAF/CRAF inhibitor, induces cell cycle arrest and apoptosis in HCT-116 cells, promising for cancer research.Formula:C25H17F6N3O2Color and Shape:SolidMolecular weight:505.41Avutometinib potassium
CAS:Avutometinib potassium, a MEKi, blocks Delta and Omicron infection in airway cells, potentially lessening disease severity.Formula:C21H17FKN5O5SColor and Shape:SolidMolecular weight:509.55MEK inhibitor
CAS:MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.Formula:C26H26N4O2Purity:97.48%Color and Shape:SolidMolecular weight:426.51Antifungal agent 46
CAS:Compound 2f (Antifungal Agent 46) is a potent antifungal that inhibits Ras signaling by targeting protein farnesyltransferase [1].Formula:C26H28BrF3N4O2Purity:98%Color and Shape:SolidMolecular weight:565.43TAK1/MAP4K2 inhibitor 1
CAS:TAK1/MAP4K2 inhibitor 1 (compound 5) is a dual kinase inhibitor of TAK1 and MAP4K2 with IC50 values of 41.1 nM and 18.2 nM, respectively.Formula:C29H31F3N6O2Purity:98%Color and Shape:SolidMolecular weight:552.59p38 MAP Kinase Inhibitor IV
CAS:p38 MAPK inhibitor IV blocks p38α/β/γ/δ with IC50s 0.13-8.63 μM and stops TNF-α/IL-1β at 22/44 nM in human cells.Formula:C12H4Cl6O4SColor and Shape:SolidMolecular weight:456.94KRAS inhibitor-10
CAS:KRAS inhibitor-10: potent, selective KRAS protein blocker; effective in various cancers; oral; tetrahydroisoquinoline class.Formula:C30H37N3O5Color and Shape:SolidMolecular weight:519.63CK1-IN-2
CAS:CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.Formula:C17H12FN3O2Purity:99.31%Color and Shape:SolidMolecular weight:309.29KRAS G12C inhibitor 45
CAS:KRAS G12C inhibitor 45 is a potent KRAS G12C inhibitor .Formula:C32H33F2N5O5SColor and Shape:SolidMolecular weight:637.7JNK3 inhibitor-4
CAS:JNK3 inhibitor-4: potent, selective JNK3 blocker (IC50=1.0nM), neuroprotective, BBB-permeable.
Formula:C28H27N7OColor and Shape:SolidMolecular weight:477.56HPK1-IN-17
CAS:HPK1-IN-17 selectively inhibits HPK1, a MAP4Ks family kinase from blood progenitor cells; useful against HPK1-related diseases like cancer.Formula:C26H28N6OColor and Shape:SolidMolecular weight:440.54KRAS inhibitor-6
CAS:KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formula:C27H30ClF2N5O3Purity:98%Color and Shape:SolidMolecular weight:546.01KRAS inhibitor-17
CAS:KRAS inhibitor-17 blocks G12C mutation (IC50: 3.37μM) and p-ERK in MIA PaCA-2 (IC50: 9.25μM). Could target pancreatic, colorectal, lung cancers.Formula:C21H18Cl2FN3O2SColor and Shape:SolidMolecular weight:466.36BRAF V600E/CRAF-IN-2
CAS:Potent BRAFV600E/CRAF inhibitor, IC50: 0.888/0.229 μM, induces G0/G1 arrest and apoptosis in HCT-116 cells, potential for cancer research.Formula:C30H30F3N5O2Color and Shape:SolidMolecular weight:549.59(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Formula:C18H18O4Purity:98.91% - 99.42%Color and Shape:SolidMolecular weight:298.33REDX05358
CAS:REDX05358: Selective pan RAF inhibitor for BRAF/RAS mutant tumors with high affinity, safety, and low paradoxical activation.Formula:C26H21ClN4O3Color and Shape:SolidMolecular weight:472.92KRAS4b-PDEδ stabilizer C19
CAS:KRAS4b-PDEδ stabilizer C19 is a stabilizer of the KRAS4b-PDEδ complex which decreases the proliferation of colorectal cancer cells, and increases apoptosis viaFormula:C18H20Cl2N2O3Color and Shape:SolidMolecular weight:383.27MEK-IN-4
CAS:MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.Formula:C21H18N4OSPurity:98.35% - 99.16%Color and Shape:SolidMolecular weight:374.46KRAS inhibitor-3
CAS:KRAS inhibitor-3 targets WT/oncogenic KRAS; high affinity (KD: 0.28-0.74 μM); disrupts KRAS-Raf interaction.Formula:C25H27N5OColor and Shape:SolidMolecular weight:413.51SCH 51344
CAS:SCH 51344 inhibits Ras induced malignant transformation. SCH 51344 prevents anchorage-independent growth of oncogene transformed fibroblasts [1].Formula:C16H20N4O3Color and Shape:SolidMolecular weight:316.36BAY-846
CAS:BAY-846: allosteric MEK inhibitor, long-lasting, highly bioavailable, low brain entry, effective in K-Ras A549 model.Formula:C19H13F4IN4O4SColor and Shape:SolidMolecular weight:596.29Ras modulator-1
CAS:Ras modulator-1 is a modulator of Ras.Formula:C29H21N5O4SColor and Shape:SolidMolecular weight:535.57Nek2-IN-5
CAS:Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).Formula:C15H12N6OPurity:98.11%Color and Shape:SolidMolecular weight:292.3Spiclomazine HCl
CAS:Spiclomazine HCl induced apoptosis in pancreatic cancer cells, which was generally related to cell viability, migration, and invasion.Formula:C22H25Cl2N3OS2Color and Shape:SolidMolecular weight:482.49LX-3
CAS:LX-3 activates p38 MAPK, enabling expression of genes normally silenced by DNA methylation.Formula:C20H13BrN4OSColor and Shape:SolidMolecular weight:437.31VU0424465
CAS:VU0424465 is a mGlu5-selective allosteric agonist.Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36KRAS G12C inhibitor 47
CAS:KRAS G12C inhibitor 47 strongly blocks KRAS G12C (IC50: 0.172 μM) and p-ERK in cells; promising for pancreatic, colorectal, lung cancers.Formula:C30H28ClFN4O3Color and Shape:SolidMolecular weight:547.02NSC-70220
CAS:SOS1-IN-1 is an inhibitor of SOS1.Formula:C22H15NO2Purity:98%Color and Shape:SolidMolecular weight:325.36SOS1-IN-3
CAS:SOS1-IN-3 is an effective inhibitor of SOS1 (son of sevenless homolog 1) (IC50=5 nM). SOS1-IN-3 shows antitumor activity.Formula:C21H21F3N4OColor and Shape:SolidMolecular weight:402.41PF-04880594
CAS:PF-04880594 is a potent and selective RAF inhibitor which inhibits both wild-type and mutant BRAF and CRAF. PF-04880594 exhibits antitumor activity [1].Formula:C19H16F2N8Color and Shape:SolidMolecular weight:394.38SOS1 activator 1
CAS:SOS1 activator 1 enhances SOS1's GDP-GTP exchange on Ras (Kd: 44 nM).Formula:C26H32ClFN6Color and Shape:SolidMolecular weight:483.02BRAF inhibitor
CAS:BRAF inhibitor is an inhibitor of B-Raf.Formula:C22H18F2N4O3SPurity:98.2% - 98.41%Color and Shape:SolidMolecular weight:456.47Ref: TM-T10599
1mg44.00€5mg87.00€10mg137.00€25mg236.00€50mg371.00€100mg530.00€200mg770.00€1mL*10mM (DMSO)99.00€KRAS G12C inhibitor 48
KRAS G12C inhibitor 48: potent with IC50 639.91 nM; hampers H358, H23, A549 cell growth with IC50s of 0.796, 6.33, 16.14 µM, respectively.Formula:C36H39ClN8O2Color and Shape:SolidMolecular weight:651.2KRas G12C inhibitor 3
CAS:KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.Formula:C32H36ClN7O2Purity:98%Color and Shape:SolidMolecular weight:586.13KRAS G12C inhibitor 31
CAS:KRAS G12C inhibitor 31 is an inhibitor of KRAS G12C that can be used to study cancer.Formula:C25H22ClFN6O3Color and Shape:SolidMolecular weight:508.933,4-Dephostatin
CAS:3,4-Dephostatin is an inhibitor of the interactions of CFTR-associated ligand (CAL) and PSD-95/Dlg1/ZO-1 (PDZ) domain.Formula:C7H8N2O3Color and Shape:SolidMolecular weight:168.156-T-GDP
CAS:6-T-GDP (6-Thioguanosine 5'-diphosphate) is a metabolite of thiopurine. It inhibits the activity of Rac1, thereby reducing the transcription of inflammatory factors and the expression of cell adhesion molecules, which ultimately suppresses leukocyte migration and the occurrence of tissue inflammation.Formula:C10H15N5O10P2SColor and Shape:SolidMolecular weight:459.27GDC-0879
CAS:GDC-0879 (AR-00341677) is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.Formula:C19H18N4O2Purity:99.62%Color and Shape:SolidMolecular weight:334.37Ref: TM-T6320
1mg35.00€2mg50.00€5mg74.00€10mg105.00€25mg205.00€50mg334.00€100mg537.00€200mg765.00€1mL*10mM (DMSO)82.00€RMM-46
CAS:RMM-46 is a reversible covalent inhibitor with high ligand efficiency and selectivity for MSK/RSK family kinases.Formula:C24H26N4O5Purity:98.89%Color and Shape:SolidMolecular weight:450.49KRas G12C inhibitor 4
CAS:KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15Tpl2-IN-I
CAS:Tpl2-IN-I is an inhibitor of tumour progression locus 2 (Tpl2) kinase.Formula:C21H14ClFN6Purity:98%Color and Shape:SolidMolecular weight:404.83NSC1011
CAS:NSC1011 is an inhibitor of ras converting enzyme 1 (Rce1).Formula:C23H18N2O3Purity:98%Color and Shape:SolidMolecular weight:370.4AZD6703 free base
CAS:AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14).Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5Kobe2601
CAS:Kobe2601 is a Kobe0065 and Kobe02602 water-soluble analog. It displays inhibitory activity towards Ras-Raf binding.Formula:C13H10FN5O4SPurity:98%Color and Shape:SolidMolecular weight:351.31GSK329
CAS:GSK329 selectively inhibits TNNI3K, showing cardioprotection in ischemic heart models.Formula:C19H14Cl2F3N5O2Purity:98%Color and Shape:SolidMolecular weight:472.25Ref: TM-T24109
1mg50.00€2mg72.00€5mg110.00€10mg173.00€25mg295.00€50mg424.00€100mg577.00€200mg778.00€1mL*10mM (DMSO)130.00€HCI-2184
CAS:HCI-2184 is an inhibitor of AXL kinase and Nek2 that acts by successfully mitigating drug resistance in bortezomib-resistant multiple myeloma.Formula:C23H28ClN7O2SPurity:98%Color and Shape:SolidMolecular weight:502.03GSK649A
CAS:GSK649A is a novel activator of Satellite Cell Proliferation, it could enhance repair of Damaged Muscle.Formula:C15H12ClFN6OSPurity:98%Color and Shape:SolidMolecular weight:378.81CP-281384
CAS:CP-281384 is a potent, p38alpha-selective inhibitor.Formula:C18H14F2N4OPurity:98%Color and Shape:SolidMolecular weight:340.33mSIRK
CAS:mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit dissociation.Formula:C93H150N20O25Purity:99.26%Color and Shape:SolidMolecular weight:1948.31RBC6
CAS:RBC6 is an inhibitor of the binding of Ral to its effector RALBP1.Formula:C16H14Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:365.21MW108
CAS:MW108 is an active site targeted, CNS-active, p38αMAPK inhibitor.Formula:C21H19ClN4Color and Shape:SolidMolecular weight:362.86L-167307
CAS:L-167307 is a p38 kinase inhibitor.Formula:C22H17FN2OSPurity:98%Color and Shape:SolidMolecular weight:376.45CP-944629
CAS:CP-944629 is a novel, potent, and selective inhibitor of p38alpha.Formula:C19H15F3N4OPurity:98%Color and Shape:SolidMolecular weight:372.34BNC-1
CAS:BNC-1 reduces amyloid in mice, enhances synapses by activating Elk-1.Formula:C16H14N2O3Purity:98%Color and Shape:SolidMolecular weight:282.29KRAS4b-IN-D14
CAS:KRAS4b-IN-D14 inhibits oncogenic KRAS4b, shrinks tumors, and induces cancer cell apoptosis.Formula:C24H24ClN5O4Color and Shape:SolidMolecular weight:481.93KB-5246
CAS:KB-5246, displays antibacterial activities.is a tetracyclic quinolone.Formula:C18H17ClFN3O4SPurity:98%Color and Shape:SolidMolecular weight:425.86HPK1-IN-15
CAS:HPK1-IN-15 selectively inhibits HPK1, a MAP4K family kinase, potentially aiding in cancer treatment.Formula:C24H21ClF3N5Color and Shape:SolidMolecular weight:471.91KRAS G12D inhibitor 13
CAS:KRAS G12D inhibitor 13 targets KRAS G12D-mediated cancers with potency (WO2021108683A1, cmpd 142).Formula:C31H33F2N7O3Color and Shape:SolidMolecular weight:589.64B-Raf IN 7
CAS:"B-Raf IN 7 inhibits B-Raf (IC50: 110.23 nM); fights colon, breast, liver, cervical, prostate cancers (IC50: 7.50-12.83 μM)."Formula:C15H16N6O3Color and Shape:SolidMolecular weight:328.33ERK1/2 inhibitor 1
CAS:ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
Formula:C29H32ClN5O4Purity:98.81%Color and Shape:SolidMolecular weight:550.05PF-05381941
CAS:PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.Formula:C27H26N6O2Purity:98.04%Color and Shape:SolidMolecular weight:466.53MEK-IN-1
CAS:MEK-IN-1 is a MEK inhibitor.Formula:C24H20N4O4Purity:98%Color and Shape:SolidMolecular weight:428.44PAF (C16)
CAS:PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.Formula:C26H54NO7PPurity:98%Color and Shape:SolidMolecular weight:523.68B-Raf IN 13
CAS:B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.
Formula:C19H19ClFN3O4SPurity:99.41% - >99.99%Color and Shape:SoildMolecular weight:439.89KRAS G12D inhibitor 10
CAS:KRAS G12D inhibitor 10 targets KRAS G12D in cancer research (WO2021108683A1, compound 34).Formula:C33H41ClN8O2Color and Shape:SolidMolecular weight:617.18KRAS G12C inhibitor 42
CAS:KRAS G12C inhibitor 42 targets KRAS G12C for potential cancer therapy. (Patent WO2020146613A1, compound 10)Formula:C33H34FN7O2Color and Shape:SolidMolecular weight:579.67(S)-CCG-1423
(S)-CCG-1423, a stereoisomer, inhibits Rho to block myocardin-related transcription factor A & serum response signaling.Formula:C18H13ClF6N2O3Purity:98%Color and Shape:SolidMolecular weight:454.8TOPK-p38/JNK-IN-1
CAS:TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NOFormula:C17H15F3N2O4Color and Shape:SolidMolecular weight:368.31p38-α MAPK-IN-4
CAS:p38-α MAPK-IN-4 (Compound 69) is a selective inhibitor of p38α MAPK, demonstrating potent inhibition with an IC50 of 1.5 μM.Formula:C17H13BrN2OColor and Shape:SolidMolecular weight:341.2LCRF-0004
CAS:LCRF-0004 inhibits RON kinase, key in KRAS-driven pancreatic cancer, reducing cell migration and enhancing chemo sensitivity.Formula:C28H18F4N6O2SColor and Shape:SolidMolecular weight:578.54Cuspin-1
CAS:Cuspin-1, a small molecule, increases SMN levels by 50% in SMA by boosting ERK phosphorylation and Ras-Raf-MEK signaling.Formula:C13H10BrNOColor and Shape:SolidMolecular weight:276.13GGTI-286
CAS:GGTI-286: GGTase I inhibitor, cell-permeable, IC50=2μM. Strongly blocks Rap1A geranylation; less effective on H-Ras, Ras4B IC50=1μM.Formula:C23H31N3O3SColor and Shape:SolidMolecular weight:429.58KRAS G12C inhibitor 39
CAS:KRAS G12C inhibitor 39 effectively targets KRAS G12C, a key protein in cancer research.Formula:C37H43N9O2Color and Shape:SolidMolecular weight:645.8(2Z,3Z)-U0126
CAS:U0126 selectively inhibits MEK1/2, blocks MAPK/ERK signaling, and suppresses Ki-ras-induced cell growth, with IC50s of 72 nM and 58 nM for MEK1/2.Formula:C18H16N6S2Color and Shape:SolidMolecular weight:380.49MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formula:C33H36N2O3Purity:97.23%Color and Shape:OilMolecular weight:508.65Ref: TM-T24437
1mg34.00€5mg92.00€10mg160.00€25mg276.00€50mg400.00€100mg532.00€500mg1,063.00€1mL*10mM (DMSO)103.00€KYA1797
CAS:KYA1797 inhibits Wnt/ß-catenin, targeting axin, and promotes ß-catenin/Ras decay, halting APC/KRAS mutant CRC growth.Formula:C17H12N2O6S2Purity:98%Color and Shape:SolidMolecular weight:404.42RSK2-IN-2
CAS:RSK2-IN-2 (Compound 25) is a reversible covalent inhibitor of the RPS6KA3 ( RSK2 ) kinase which also inhibits MSK1, MSK2, and RSK3 [1].Formula:C16H11N5OColor and Shape:SolidMolecular weight:289.29GABAB receptor antagonist 1
CAS:(E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM.GABAB receptor antagonist 1 is a selectiveFormula:C18H24O4Purity:98%Color and Shape:SolidMolecular weight:304.38B-Raf IN 8
CAS:B-Raf IN 8: strong B-Raf inhibitor (70.65 nM IC50); combats liver, colon, breast & prostate cancer with IC50s from 9.78 to 29.85 μM.Formula:C18H17N3O2Color and Shape:SolidMolecular weight:307.35(E)-GABAB receptor antagonist 1
CAS:(E)-GABAB antagonist 1 inhibits GABA IP3 production, with an IC50 of 37.9 μM and acts as a selective negative modulator.Formula:C18H24O4Purity:98.09%Color and Shape:SolidMolecular weight:304.38Ref: TM-T11137
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg472.00€100mg645.00€1mL*10mM (DMSO)153.00€p38 MAPK Inhibitor
CAS:p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.Formula:C20H13ClFN3OPurity:99.91%Color and Shape:SolidMolecular weight:365.79Ref: TM-T36010
1mg92.00€5mg279.00€10mg434.00€25mg642.00€50mg880.00€100mg1,170.00€200mg1,594.00€500µg56.00€DS12881479
CAS:DS12881479 can be used in cancer research which is a potent and selective inhibitor of Mnk1(IC 50 =21 nM) [1].Formula:C16H19N3OSPurity:99.85%Color and Shape:SolidMolecular weight:301.41MKK7-COV-9
CAS:MKK7-COV-9 is an MKK7 inhibitor that inhibits MKK7-induced protein-protein interactions and interrupts the activation of primary B cells in response to LPS.Formula:C18H16N4O2Purity:99.73% - 99.83%Color and Shape:SolidMolecular weight:320.35Ref: TM-T60857
2mg145.00€5mg235.00€10mg376.00€25mg747.00€50mg1,121.00€100mg1,768.00€1mL*10mM (DMSO)259.00€p38α inhibitor 4
CAS:p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.Formula:C14H7F6N3OPurity:99.69%Color and Shape:SolidMolecular weight:347.215Cot inhibitor-1
CAS:Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.Formula:C27H27Cl2FN8Purity:98.87%Color and Shape:SolidMolecular weight:553.46Ref: TM-T10865
1mg73.00€5mg152.00€10mg222.00€25mg401.00€50mg602.00€100mg887.00€200mg1,215.00€1mL*10mM (DMSO)177.00€JNK-IN-11
CAS:JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.Formula:C12H11NO3S2Purity:98.82%Color and Shape:SolidMolecular weight:281.35UR13870
CAS:UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.Formula:C24H16F2N4Purity:99.18% - >99.99%Color and Shape:SolidMolecular weight:398.41AKP-001
CAS:AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.Formula:C21H13ClF2N4O2Purity:99.50% - 99.92%Color and Shape:SolidMolecular weight:426.8SOS1-IN-15
CAS:SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used in the study of colon cancer.Formula:C28H27F3N6O2Purity:98.32%Color and Shape:SolidMolecular weight:536.548EO-1606
CAS:EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.Formula:C21H17ClFNOPurity:98.28% - 98.84%Color and Shape:SolidMolecular weight:353.82ZINC12409120
CAS:ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23Formula:C20H16N4O2Purity:99.71% - 99.95%Color and Shape:SolidMolecular weight:344.37Ref: TM-T61122
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€
