MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 893 products of "MAPK"
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D-JNKI-1 acetate
D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.Formula:C166H290N66O42Purity:99.48%Color and Shape:SolidMolecular weight:3882.5Ref: TM-T10937L
1mg156.00€5mg296.00€10mg442.00€25mg707.00€50mg1,009.00€100mg1,333.00€1mL*10mM (DMSO)1,089.00€methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate
CAS:methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate is a biochemical.Formula:C13H13NO5Purity:97.69%Color and Shape:SolidMolecular weight:263.25Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513Ref: TM-T12871
1mg50.00€2mg73.00€5mg109.00€10mg168.00€25mg358.00€50mg530.00€100mg758.00€1mL*10mM (DMSO)124.00€Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25Ref: TM-T6427
1mg40.00€2mg52.00€5mg84.00€10mg101.00€25mg202.00€50mg326.00€100mg520.00€1mL*10mM (DMSO)82.00€SGX-523
CAS:SGX-523 is a selective Met inhibitor (IC50: 4 nM), no inhibitory to Abl, BRAFV599E, p38α, and c-Raf.
Formula:C18H13N7SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:359.41Nardosinone
CAS:Nardosinone inhibits H9c2 cell hypertrophy, protects neurons from OGD, and boosts neurite outgrowth by modifying key signaling pathways.Formula:C15H22O3Purity:98.82% - 99%Color and Shape:SolidMolecular weight:250.33Cefotetan
CAS:Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.Formula:C17H17N7O8S4Purity:95.72% - 99.38%Color and Shape:SolidMolecular weight:575.62I-49 free base
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novelFormula:C23H26ClF3N4O2Purity:99.64% - 99.88%Color and Shape:SolidMolecular weight:482.92Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48Ref: TM-T7558
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg178.00€50mg234.00€100mg303.00€1mL*10mM (DMSO)78.00€BI-882370
CAS:BI-882370 is a specific RAF kinase inhibitor.Formula:C28H33F2N7O2SPurity:97.33% - 99.07%Color and Shape:SolidMolecular weight:569.67Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Formula:C8H10NO6PPurity:97.52%Color and Shape:SolidMolecular weight:247.14PF-06260933 HCl
CAS:PF-06260933 Dihydrochloride, a MAP4K4 inhibitor, hinders HGK, Mink, Tnik (IC50s: 140, 8, 13 nM) and lessens mouse fasting hyperglycemia.Formula:C16H15Cl3N4Color and Shape:SolidMolecular weight:369.68Kobe2602
CAS:Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.Formula:C14H9F4N5O4SPurity:98.36% - 99.39%Color and Shape:SolidMolecular weight:419.31NG25 trihydrochloride
CAS:NG25 trihydrochloride: kinase inhibitor for MAP4K2, TAK1, Src, LYN, Abl, CSK, FER, p38α; blocks TNF-α signals; impedes IFN secretion; anti-cancer properties.Formula:C29H33Cl3F3N5O2Color and Shape:SolidMolecular weight:646.96Belvarafenib
CAS:Belvarafenib (HM95573) is a potent pan-RAF inhibitor with antitumor activity and inhibits B-RAF, B-RAFv600E, and C-RAF.Cost-effective and quality-assured.Formula:C23H16ClFN6OSPurity:98% - 99.65%Color and Shape:SolidMolecular weight:478.93GSK-114
CAS:GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.Formula:C19H23N5O4SPurity:99.51%Color and Shape:SolidMolecular weight:417.48RAF709
CAS:RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.Formula:C28H29F3N4O4Purity:99.28% - 99.8%Color and Shape:SolidMolecular weight:542.55Ref: TM-T3711
1mg38.00€2mg50.00€5mg82.00€10mg124.00€25mg245.00€50mg401.00€100mg592.00€500mg1,243.00€1mL*10mM (DMSO)88.00€PF-06260933
CAS:PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.
Formula:C16H13ClN4Purity:99.63% - 99.97%Color and Shape:SolidMolecular weight:296.75AZD8330
CAS:AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.Formula:C16H17FIN3O4Purity:98.72%Color and Shape:SolidMolecular weight:461.23
