MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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R1487
CAS:449811-92-1
R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.
Formula:
C19H18F2N4O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
388.37
Ref: TM-T7667
| 1mg | 128.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 421.00 € | ||
| 25mg | 694.00 € | ||
| 50mg | 979.00 € | ||
| 100mg | 1,324.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Regorafenib monohydrate
CAS:1019206-88-2
Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, …
Formula:
C21H17ClF4N4O4
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
500.83
Ref: TM-T1792L
| 5mg | 36.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 204.00 € | ||
| 500mg | 348.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GNE-495
CAS:1449277-10-4
GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).
Formula:
C22H20FN5O2
Purity:
98.23% - 99.22%
Color and Shape:
Solid
Molecular weight:
405.42
Ref: TM-TQ0079
| 1mg | 72.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 143.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TA-01
CAS:1784751-18-3
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 …
Formula:
C20H12F3N3
Purity:
98.77% - 99.94%
Color and Shape:
Solid
Molecular weight:
351.32
Ref: TM-T4645
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 318.00 € | ||
| 200mg | 447.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
(E/Z)-Necrosulfonamide
CAS:432531-71-0
(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.
Formula:
C18H15N5O6S2
Purity:
97.62% - 98%
Color and Shape:
Solid
Molecular weight:
461.47
Ref: TM-T7129
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 286.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SCH772984
CAS:942183-80-4
SCH772984 is an ERK inhibitor and is highly selective and ATP-competitive. SCH772984 exhibits antitumor activity. …
Formula:
C33H33N9O2
Purity:
97.65% - 98.75%
Color and Shape:
Solid
Molecular weight:
587.67
Ref: TM-T6066
| 1mg | 52.00 € | ||
| 2mg | 76.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 146.00 € | ||
| 25mg | 286.00 € | ||
| 50mg | 429.00 € | ||
| 100mg | 628.00 € | ||
| 200mg | 896.00 € | ||
| 500mg | 1,336.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Kobe2602
CAS:454453-49-7
Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.
Formula:
C14H9F4N5O4S
Purity:
98.36% - 99.39%
Color and Shape:
Solid
Molecular weight:
419.31
Ref: TM-T1892
| 10mg | 40.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 81.00 € | ||
| 100mg | 122.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MK2-IN-1 hydrochloride
CAS:1314118-94-9
MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.
Formula:
C27H26Cl2N4O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
509.43
Ref: TM-T4442
| 5mg | 36.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 104.00 € | ||
| 50mg | 175.00 € | ||
| 100mg | 263.00 € | ||
| 200mg | 383.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AD80
CAS:1384071-99-1
AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.
Formula:
C22H19F4N7O
Purity:
100% - 99.9%
Color and Shape:
Solid
Molecular weight:
473.43
Ref: TM-T4301
| 1mg | 46.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 146.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 682.00 € | ||
| 200mg | 547.00 € | ||
| 500mg | 1,375.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tauroursodeoxycholate dihydrate
CAS:117609-50-4
Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor.
Formula:
C26H49NO8S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
535.73
Ref: TM-T16998
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SCH54292
CAS:188480-51-5
SCH-54292 is a GDP exchange inhibitor.
Formula:
C24H28N2O9S
Purity:
95.65%
Color and Shape:
Solid
Molecular weight:
520.55
Ref: TM-T9198
| 1mg | 129.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 420.00 € | ||
| 25mg | 692.00 € | ||
| 50mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 362.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
UM-164
CAS:903564-48-7
UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, …
Formula:
C30H31F3N8O3S
Purity:
98.72% - 99.52%
Color and Shape:
Solid
Molecular weight:
640.68
Ref: TM-T4597
| 1mg | 35.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 277.00 € | ||
| 100mg | 409.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
1-(4-methansulfinylphenyl)ethanone
CAS:32361-73-2
The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.
Formula:
C9H10O2S
Purity:
99.48%
Color and Shape:
Solid
Molecular weight:
182.24
Ref: TM-T8870
| 1mg | 50.00 € | ||
| 5mg | 147.00 € | ||
| 10mg | 199.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 389.00 € | ||
| 100mg | 542.00 € | ||
| 200mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GS87
CAS:919936-70-2
GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive …
Formula:
C16H11N5O2S
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
337.36
Ref: TM-T8605
| 1mg | 130.00 € | ||
| 2mg | 185.00 € | ||
| 5mg | 279.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 701.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,332.00 € | ||
| 1mL*10mM (DMSO) | 294.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cichoric Acid
CAS:6537-80-0
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase …
Formula:
C22H18O12
Purity:
97.87% - 98.57%
Color and Shape:
Solid
Molecular weight:
474.37
Ref: TM-TL0006
| 5mg | 41.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 278.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Compound 3344 hydrochloride
Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
Formula:
C24H27ClN2O3
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
426.94
Ref: TM-T9184L
| 1mg | 141.00 € | ||
| 5mg | 278.00 € | ||
| 10mg | 416.00 € | ||
| 25mg | 686.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,287.00 € | ||
| 1mL*10mM (DMSO) | 334.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
L-779450
CAS:303727-31-3
L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and …
Formula:
C20H14ClN3O
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
347.8
Ref: TM-T1953
| 2mg | 54.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IACS-13909
CAS:2160546-07-4
IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the …
Formula:
C17H18Cl2N6
Purity:
98.80%
Color and Shape:
Solid
Molecular weight:
377.27
Ref: TM-T9196
| 1mg | 93.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 353.00 € | ||
| 25mg | 501.00 € | ||
| 50mg | 709.00 € | ||
| 100mg | 918.00 € | ||
| 1mL*10mM (DMSO) | 249.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sauchinone
CAS:177931-17-8
Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.
Formula:
C20H20O6
Purity:
100%
Color and Shape:
Solid
Molecular weight:
356.37
Ref: TM-T6S1572
| 1mg | 35.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 298.00 € | ||
| 100mg | 444.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Asperulosidic acid
CAS:25368-11-0
Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition …
Formula:
C18H24O12
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
432.38
Ref: TM-TN1410
| 1mg | 150.00 € | ||
| 5mg | 310.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 837.00 € | ||
| 50mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 346.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
