MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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NG25
CAS:1315355-93-1
NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and …
Formula:
C29H30F3N5O2
Purity:
97.59% - ≥95%
Color and Shape:
Solid
Molecular weight:
537.58
Ref: TM-T5643
| 1mg | 85.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 492.00 € | ||
| 50mg | 701.00 € | ||
| 100mg | 918.00 € | ||
| 500mg | 1,841.00 € | ||
| 1mL*10mM (DMSO) | 184.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CC-90001
CAS:1403859-14-2
CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over …
Formula:
C16H27N5O2
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
321.42
Ref: TM-T9688
| 1mg | 154.00 € | ||
| 5mg | 315.00 € | ||
| 10mg | 501.00 € | ||
| 25mg | 807.00 € | ||
| 50mg | 1,106.00 € | ||
| 100mg | 1,476.00 € | ||
| 1mL*10mM (DMSO) | 352.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CAFESTOL
CAS:469-83-0
Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.
Formula:
C20H28O3
Purity:
97.06% - 99.08%
Color and Shape:
Solid
Molecular weight:
316.43
Ref: TM-T5727
| 2mg | 38.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 225.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
2,5-Dihydroxyacetophenone
CAS:490-78-8
2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.
Formula:
C8H8O3
Purity:
99.91%
Color and Shape:
Yellow Powder
Molecular weight:
152.15
Ref: TM-TCS2170
| 50mg | 35.00 € | ||
| 100mg | 49.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CCT196969
CAS:1163719-56-9
CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, …
Formula:
C27H24FN7O3
Purity:
98.58% - 99.65%
Color and Shape:
Solid
Molecular weight:
513.52
Ref: TM-T4133
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 398.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Galangin
CAS:548-83-4
Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 …
Formula:
C15H10O5
Purity:
98.24% - 99.93%
Color and Shape:
Yellowish Needle-Like Crystal
Molecular weight:
270.24
Ref: TM-T3668
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 119.00 € | ||
| 100mg | 202.00 € | ||
| 500mg | 505.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
XMD8-92
CAS:1234480-50-2
XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).
Formula:
C26H30N6O3
Purity:
98.19%
Color and Shape:
Solid
Molecular weight:
474.55
Ref: TM-T1843
| 5mg | 52.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 385.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Talmapimod
CAS:309913-83-5
Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold …
Formula:
C27H30ClFN4O3
Purity:
100% - 98%
Color and Shape:
Solid
Molecular weight:
513
Ref: TM-T12871
| 1mg | 52.00 € | ||
| 2mg | 76.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 786.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EF24
CAS:342808-40-6
EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in …
Formula:
C19H15F2NO
Purity:
98.47%
Color and Shape:
Solid
Molecular weight:
311.33
Ref: TM-T27242
| 1g | 1,491.00 € | ||
| 1mg | 40.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 527.00 € | ||
| 500mg | 1,116.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AS601245
CAS:345987-15-7
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.
Formula:
C20H16N6S
Purity:
98% - 99.02%
Color and Shape:
Solid
Molecular weight:
372.45
Ref: TM-T2343
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 166.00 € | ||
| 25mg | 268.00 € | ||
| 50mg | 398.00 € | ||
| 100mg | 592.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VX-11e
CAS:896720-20-0
VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; …
Formula:
C24H20Cl2FN5O2
Purity:
98.92% - ≥98%
Color and Shape:
Solid
Molecular weight:
500.35
Ref: TM-T3166
| 2mg | 54.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 544.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ulixertinib
CAS:869886-67-9
Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib …
Formula:
C21H22Cl2N4O2
Purity:
99.41% - 99.95%
Color and Shape:
Solid
Molecular weight:
433.33
Ref: TM-T7005
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 183.00 € | ||
| 100mg | 347.00 € | ||
| 200mg | 503.00 € | ||
| 500mg | 796.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
I-49 free base
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel
Formula:
C23H26ClF3N4O2
Purity:
99.64% - 99.88%
Color and Shape:
Solid
Molecular weight:
482.92
Ref: TM-T8746L
| 1mg | 128.00 € | ||
| 5mg | 281.00 € | ||
| 10mg | 424.00 € | ||
| 25mg | 698.00 € | ||
| 50mg | 981.00 € | ||
| 1mL*10mM (DMSO) | 348.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
JNK Inhibitor VIII
CAS:894804-07-0
JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase …
Formula:
C18H20N4O4
Purity:
98.93%
Color and Shape:
Solid
Molecular weight:
356.38
Ref: TM-T7677
| 1mg | 59.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 323.00 € | ||
| 50mg | 479.00 € | ||
| 100mg | 684.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Farrerol
CAS:24211-30-1
Farrerol shows antioxidative effects, modulates genes, fights S. aureus in cows, protects cells, and may …
Formula:
C17H16O5
Purity:
99.89% - 99.96%
Color and Shape:
Solid
Molecular weight:
300.31
Ref: TM-T6S0525
| 20mg | 107.00 € | ||
| 1mL*10mM (DMSO) | 77.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Refametinib
CAS:923032-37-5
Refametinib (RDEA119) (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 …
Formula:
C19H20F3IN2O5S
Purity:
100% - 99.84%
Color and Shape:
Solid
Molecular weight:
572.34
Ref: TM-T6636
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 415.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CID-1067700
CAS:314042-01-8
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 …
Formula:
C18H18N2O4S2
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
390.48
Ref: TM-T7558
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 241.00 € | ||
| 100mg | 312.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
N-tert-butyl-α-Phenylnitrone
CAS:3376-24-7
N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.
Formula:
C11H15NO
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
177.24
Ref: TM-T23046
| 50mg | 43.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 84.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CAY10404
CAS:340267-36-9
CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.
Formula:
C17H12F3NO3S
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
367.34
Ref: TM-T8656
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 292.00 € | ||
| 100mg | 422.00 € | ||
| 200mg | 593.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Effusanin A
CAS:30220-43-0
Effusanin A: antibacterial, damages DNA, inhibits DU145 cells at 3.16 μM and LoVo cells at …
Formula:
C20H28O5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
348.43
Ref: TM-TN3920
| 1mg | 169.00 € | ||
| 5mg | 347.00 € | ||
| 10mg | 520.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
