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MAPK

MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

Found 881 products of "MAPK"

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  • Plx-4032
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    Plx-4032

    CAS:
    Plx-4032 (Vemurafenib) is a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
    Formula:C23H18ClF2N3O3S
    Purity:98.53% - 99.36%
    Color and Shape:Solid
    Molecular weight:489.92

    Ref: TM-T8654

  • 6H05 (TFA)
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    6H05 (TFA)

    CAS:
    <p>6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.</p>
    Formula:C22H31ClF3N3O4S3
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:590.14

    Ref: TM-T7326

  • ML-098
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    ML-098

    CAS:
    <p>ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).</p>
    Formula:C19H19NO3
    Purity:99.06% - 99.23%
    Color and Shape:Solid
    Molecular weight:309.36

    Ref: TM-T4619

  • KRPEP-2D acetate
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    KRPEP-2D acetate

    <p>KRPEP-2D acetate: inhibitor targeting K-Ras(G12D) mutant, a crucial cancer-related protein.</p>
    Formula:C110H186N44O27S2
    Purity:98.94%
    Color and Shape:Solid
    Molecular weight:2621.06

    Ref: TM-TP2358

  • CCT196969
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    CCT196969

    CAS:
    <p>CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.</p>
    Formula:C27H24FN7O3
    Purity:98.93% - 99.65%
    Color and Shape:Solid
    Molecular weight:513.52

    Ref: TM-T4133

  • Talmapimod
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    Talmapimod

    CAS:
    <p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), &gt;2000-fold selectivity over 20 kinases.</p>
    Formula:C27H30ClFN4O3
    Purity:98% - 99.9%
    Color and Shape:Solid
    Molecular weight:513

    Ref: TM-T12871

  • 1-(4-methansulfinylphenyl)ethanone
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    1-(4-methansulfinylphenyl)ethanone

    CAS:
    <p>The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.</p>
    Formula:C9H10O2S
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:182.24

    Ref: TM-T8870

  • CMPD1
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    CMPD1

    CAS:
    <p>CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).</p>
    Formula:C22H20FNO2
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:349.4

    Ref: TM-T14988

  • Temuterkib
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    Temuterkib

    CAS:
    <p>LY3214996 (Temuterkib) is a potent oral ERK1/2 inhibitor with potential cancer-fighting properties.</p>
    Formula:C22H27N7O2S
    Purity:99.57% - >99.99%
    Color and Shape:Solid
    Molecular weight:453.56

    Ref: TM-T4091

  • MK2-IN-3
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    MK2-IN-3

    CAS:
    <p>MK2-IN-3 is a potent MK-2 inhibitor, cell-permeable, for rheumatoid arthritis treatment.</p>
    Formula:C21H16N4O
    Purity:99.01%
    Color and Shape:Solid
    Molecular weight:340.38

    Ref: TM-T9034

  • AS601245
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    AS601245

    CAS:
    <p>AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.</p>
    Formula:C20H16N6S
    Purity:98% - 99.02%
    Color and Shape:Solid
    Molecular weight:372.45

    Ref: TM-T2343

  • I-49 free base
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    I-49 free base

    I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel
    Formula:C23H26ClF3N4O2
    Purity:99.64% - 99.88%
    Color and Shape:Solid
    Molecular weight:482.92

    Ref: TM-T8746L

  • SD 0006
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    SD 0006

    CAS:
    <p>SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.</p>
    Formula:C20H20ClN5O2
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:397.86

    Ref: TM-T7276

  • Deltarasin HCl
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    Deltarasin HCl

    CAS:
    <p>Deltarasin hinders KRAS-PDEδ, impairs cancer cell growth via a PDEδ pocket, disrupting RAS/RAF signaling and autophagy.</p>
    Formula:C40H37N5O·xHCl
    Color and Shape:Solid
    Molecular weight:713.144

    Ref: TM-T70646

  • ASK1-IN-1
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    ASK1-IN-1

    CAS:
    ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.
    Formula:C19H19N9O2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:405.41

    Ref: TM-T9697

  • TAK-715
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    TAK-715

    CAS:
    <p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>
    Formula:C24H21N3OS
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:399.51

    Ref: TM-T6150

  • Encorafenib
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    Encorafenib

    CAS:
    Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
    Formula:C22H27ClFN7O4S
    Purity:99.51% - 99.83%
    Color and Shape:Solid
    Molecular weight:540.01

    Ref: TM-T6487

  • 1588-A4
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    1588-A4

    CAS:
    <p>1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.</p>
    Formula:C17H19BrClFN4O2
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:445.71

    Ref: TM-T22249

  • Varenicline Tartrate
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    Varenicline Tartrate

    CAS:
    <p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>
    Formula:C13H13N3·C4H6O6
    Purity:98.23% - 98.32%
    Color and Shape:Tan Solid
    Molecular weight:361.35

    Ref: TM-T1657

  • GSK-114
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    GSK-114

    CAS:
    <p>GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.</p>
    Formula:C19H23N5O4S
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:417.48

    Ref: TM-T22341