MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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B-Raf IN 13
CAS:2573782-74-6
B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an …
Formula:
C19H19ClFN3O4S
Purity:
95.83% - 98.39%
Color and Shape:
Soild
Molecular weight:
439.89
Ref: TM-T67862
| 25mg | 1,410.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
NSC-70220
CAS:4551-00-2
SOS1-IN-1 is an inhibitor of SOS1.
Formula:
C22H15NO2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
325.36
Ref: TM-T12978
| 2mg | 225.00 € | ||
| 5mg | 278.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,264.00 € | ||
| 100mg | 1,722.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
ERK1/2 inhibitor 1
CAS:2095719-90-5
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 …
Formula:
C29H32ClN5O4
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
550.05
Ref: TM-T11226
| 1mg | 122.00 € | ||
| 5mg | 295.00 € | ||
| 10mg | 426.00 € | ||
| 25mg | 653.00 € | ||
| 50mg | 873.00 € | ||
| 100mg | 1,191.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
KRAS G12D inhibitor 14
CAS:2765254-39-3
KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D …
Formula:
C20H19F3N4OS
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
420.45
Ref: TM-T62228
| 1mg | 278.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
mSIRK
CAS:593267-11-9
mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit …
Formula:
C93H150N20O25
Purity:
99.26%
Color and Shape:
Liquid
Molecular weight:
1948.31
Ref: TM-T80548
| 1mg | 46.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 413.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Antifungal agent 46
CAS:2842067-19-8
Compound 2f (Antifungal Agent 46) is a potent antifungal that inhibits Ras signaling by targeting …
Formula:
C26H28BrF3N4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
565.43
Ref: TM-T74976
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
MEK inhibitor
CAS:334951-92-7
MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity …
Formula:
C26H26N4O2
Color and Shape:
Solid
Molecular weight:
426.51
Ref: TM-T11993
| 1mg | 105.00 € | ||
| 5mg | 256.00 € | ||
| 10mg | 356.00 € | ||
| 25mg | 590.00 € | ||
| 50mg | 831.00 € | ||
| 1mL*10mM (DMSO) | 280.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PAF (C16)
CAS:74389-68-7
PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.
Formula:
C26H54NO7P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
523.68
Ref: TM-T21547
| 1mg | 73.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 21 Jan 2025
p38α inhibitor 4
CAS:1262406-08-5
p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, …
Formula:
C14H7F6N3O
Purity:
99.79%
Color and Shape:
Liquid
Molecular weight:
347.215
Ref: TM-T78652
| 1mg | 279.00 € | ||
| 5mg | 686.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
BSJ-04-122
CAS:2513289-74-0
BSJ-04-122: MKK4/7 inhibitor with IC50s of 4 nM & 181 nM, used in cancer research.
Formula:
C15H12ClN5O
Purity:
97.58%
Color and Shape:
Odour Color
Molecular weight:
313.74
Ref: TM-T73182
| 1mg | 41.00 € | ||
| 5mg | 81.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 581.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
KRas G12C inhibitor 4
CAS:2206736-07-2
KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.
Formula:
C33H38ClN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
600.15
Ref: TM-T11779
| 25mg | 1,406.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
TH-Z835
CAS:2766209-50-9
TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) …
Formula:
C30H38N6O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
498.66
Ref: TM-T78661
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
BI-2852
CAS:2375482-51-0
BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.
Formula:
C31H28N6O2
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
516.59
Ref: TM-T10533
| 1mg | 115.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 401.00 € | ||
| 25mg | 664.00 € | ||
| 50mg | 916.00 € | ||
| 100mg | 1,263.00 € | ||
| 1mL*10mM (DMSO) | 312.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
NMDAR/TRPM4-IN-2
CAS:2243506-33-2
Potent NMDAR/TRPM4-IN-2 blocks NMDAR/TRPM4, protects brain and retinal neurons, and prevents mitochondrial dysfunction with an …
Formula:
C11H19BrCl2N2
Purity:
98.77%
Color and Shape:
Odour Color
Molecular weight:
330.092
Ref: TM-T72662
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 138.00 € | ||
| 100mg | 198.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Iroxanadine
CAS:203805-20-3
Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 …
Formula:
C14H20N4O
Purity:
100% - 97.92%
Color and Shape:
Liquid
Molecular weight:
260.33
Ref: TM-T27627
| 1mg | 141.00 € | ||
| 5mg | 325.00 € | ||
| 10mg | 496.00 € | ||
| 25mg | 798.00 € | ||
| 50mg | 1,100.00 € | ||
| 100mg | 1,486.00 € | ||
| 500mg | 2,960.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
SOS1-IN-15
CAS:2793404-47-2
SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used …
Formula:
C28H27F3N6O2
Purity:
98.32%
Color and Shape:
Liquid
Molecular weight:
536.548
Ref: TM-T73164
| 1mg | 128.00 € | ||
| 5mg | 308.00 € | ||
| 10mg | 504.00 € | ||
| 25mg | 925.00 € | ||
| 50mg | 1,639.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
GDC-0879
CAS:905281-76-7
GDC-0879 (AR-00341677) is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM …
Formula:
C19H18N4O2
Purity:
95.76%
Color and Shape:
Solid
Molecular weight:
334.37
Ref: TM-T6320
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 555.00 € | ||
| 200mg | 789.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AL 8697
CAS:1057394-06-5
AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity …
Formula:
C21H21F3N4O
Purity:
98.96% - 99.26%
Color and Shape:
Solid
Molecular weight:
402.41
Ref: TM-T10277
| 1mg | 69.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 484.00 € | ||
| 100mg | 665.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Compound 3344
CAS:2368246-78-8
3344 is an inhibitor of KRAS-effector interactions,with an affnity of 126nm.
Formula:
C24H26N2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
390.47
Ref: TM-T9184
| 25mg | 862.00 € | ||
| 50mg | 1,120.00 € | ||
| 100mg | 1,681.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
KB-5246
CAS:119474-55-4
KB-5246, displays antibacterial activities.is a tetracyclic quinolone.
Formula:
C18H17ClFN3O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
425.86
Ref: TM-T11744
| 25mg | 1,549.00 € | ||
| 50mg | 2,039.00 € | ||
| 100mg | 2,619.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
