MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 881 products of "MAPK"
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TAK-715
CAS:<p>TAK-715 is a p38 MAPK inhibitor for p38α.</p>Formula:C24H21N3OSPurity:99.83%Color and Shape:SolidMolecular weight:399.51Talmapimod
CAS:<p>Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.</p>Formula:C27H30ClFN4O3Purity:98% - 99.9%Color and Shape:SolidMolecular weight:513Encorafenib
CAS:Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.Formula:C22H27ClFN7O4SPurity:99.51% - 99.83%Color and Shape:SolidMolecular weight:540.011588-A4
CAS:<p>1588-A4 (ARS-1620 Intermediate) is an intermediate of ARS-1620 which is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics.</p>Formula:C17H19BrClFN4O2Purity:98.59%Color and Shape:SolidMolecular weight:445.71PF-06260933
CAS:<p>PF-06260933 is a highly selective small-molecule MAP4K4 inhibitor with IC50s of 3.7 and 160 nM for kinase and cell, respectively.</p>Formula:C16H13ClN4Purity:99.63% - 99.97%Color and Shape:SolidMolecular weight:296.75AS601245
CAS:<p>AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.</p>Formula:C20H16N6SPurity:98% - 99.02%Color and Shape:SolidMolecular weight:372.45Varenicline Tartrate
CAS:<p>Varenicline Tartrate (CP 526555-18) is a benzazepine derivative that functions as an ALPHA4/BETA2 NICOTINIC RECEPTOR partial agonist.</p>Formula:C13H13N3·C4H6O6Purity:98.23% - 98.32%Color and Shape:Tan SolidMolecular weight:361.35Bentamapimod
CAS:<p>Bentamapimod (AS 602801) is a novel, orally active inhibitor of JNK.</p>Formula:C25H23N5O2SPurity:97.04% - 99.92%Color and Shape:SolidMolecular weight:457.55CCT196969
CAS:<p>CCT196969 is a novel orally available, pan-RAF inhibitor with anti-SRC activity. It also inhibits SRC, LCK, and the p38 MAPKs.</p>Formula:C27H24FN7O3Purity:98.93% - 99.65%Color and Shape:SolidMolecular weight:513.52XMD17-109
CAS:<p>XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).</p>Formula:C36H46N8O3Purity:98.75% - 99.7%Color and Shape:SolidMolecular weight:638.8Ulixertinib
CAS:<p>Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.</p>Formula:C21H22Cl2N4O2Purity:99.31% - 99.95%Color and Shape:SolidMolecular weight:433.33Adagrasib
CAS:<p>View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.</p>Formula:C32H35ClFN7O2Purity:99.10% - 99.9%Color and Shape:SolidMolecular weight:604.12Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formula:C15H12O5Purity:98.76% - >99.99%Color and Shape:SolidMolecular weight:272.25D-JNKI-1 acetate
<p>D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.</p>Formula:C166H290N66O42Purity:99.48%Color and Shape:SolidMolecular weight:3882.5Cefotetan
CAS:<p>Cefotetan, a cephamycin antibiotic, fights various bacteria by disrupting cell wall synthesis.</p>Formula:C17H17N7O8S4Purity:95.72% - 99.38%Color and Shape:SolidMolecular weight:575.62β-Glycerophosphate disodium salt pentahydrate
CAS:β-Glycerophosphate disodium salt pentahydrate is a protein phosphatase inhibitor.Formula:C3H7O6PH2ONaPurity:98.94% - ≥98%Color and Shape:SolidMolecular weight:306.11TAK-733
CAS:<p>TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.</p>Formula:C17H15F2IN4O4Purity:98.31% - 99.53%Color and Shape:SolidMolecular weight:504.23MRTX1133
CAS:<p>View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.</p>Formula:C33H31F3N6O2Purity:97.39% - 99.6%Color and Shape:SolidMolecular weight:600.63Pyridoxal 5'-phosphate hydrate
CAS:<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Formula:C8H10NO6PPurity:97.52%Color and Shape:SolidMolecular weight:247.14GSK-114
CAS:<p>GSK-114, a TNNI3K inhibitor with a 25 nM IC50, is 40x more selective than B-Raf and good for in vivo studies.</p>Formula:C19H23N5O4SPurity:99.51%Color and Shape:SolidMolecular weight:417.48
