MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Nek2-IN-5
CAS:1507367-00-1
Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).
Formula:
C15H12N6O
Purity:
98.11%
Color and Shape:
Solid
Molecular weight:
292.3
Ref: TM-T28141
| 1mg | 442.00 € | ||
| 5mg | 916.00 € | ||
| 10mg | 1,311.00 € | ||
| 25mg | 1,867.00 € | ||
| 50mg | 2,631.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Lucidenic acid F
CAS:98665-18-0
Lucidenic acid F as a modulator of JNK and p38, it shows potent inhibitory effects …
Formula:
C27H36O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
456.57
Ref: TM-TMA1004
| 25mg | To inquire |
Estimated delivery in United States, on Tuesday 21 Jan 2025
HS-276
CAS:2767422-72-8
HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; …
Formula:
C24H29N5O2
Purity:
98.07%
Color and Shape:
Liquid
Molecular weight:
419.52
Ref: TM-T62209
| 1mg | 88.00 € | ||
| 5mg | 198.00 € | ||
| 10mg | 310.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 794.00 € | ||
| 100mg | 1,103.00 € | ||
| 1mL*10mM (DMSO) | 222.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
KRAS inhibitor-7
CAS:2022986-68-9
KRAS inhibitor-7 is a potent KRAS G12C inhibitor.
Formula:
C26H27ClF2N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
528.98
Ref: TM-T11774
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
MEK-IN-4
CAS:297744-42-4
MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.
Formula:
C21H18N4OS
Purity:
98.67% - 99.26%
Color and Shape:
Solid
Molecular weight:
374.46
Ref: TM-T28012
| 1mg | 327.00 € | ||
| 5mg | 772.00 € | ||
| 25mg | 1,410.00 € | ||
| 50mg | 1,850.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
UR13870
CAS:755753-89-0
UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis …
Formula:
C24H16F2N4
Purity:
100% - 98.92%
Color and Shape:
Solid
Molecular weight:
398.41
Ref: TM-T29071
| 1mg | 210.00 € | ||
| 5mg | 532.00 € | ||
| 10mg | 729.00 € | ||
| 25mg | 1,158.00 € | ||
| 50mg | 1,498.00 € | ||
| 100mg | 1,934.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
GSK2008607
CAS:1244644-50-5
GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study …
Formula:
C31H28F3N7O3S2
Purity:
99%
Color and Shape:
Solid
Molecular weight:
667.72
Ref: TM-T27454
| 1mg | 325.00 € | ||
| 5mg | 772.00 € | ||
| 10mg | 1,056.00 € | ||
| 25mg | 1,476.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,322.00 € | ||
| 500mg | 4,547.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
RLX-33
CAS:2784577-71-3
RLX-33 blocks RXFP3 and relaxin 3 effects, controls food intake in rats, and may help …
Formula:
C24H19ClN4O4
Purity:
99.82%
Color and Shape:
Liquid
Molecular weight:
462.89
Ref: TM-T62929
| 1mg | 81.00 € | ||
| 5mg | 174.00 € | ||
| 10mg | 277.00 € | ||
| 25mg | 441.00 € | ||
| 50mg | 630.00 € | ||
| 100mg | 847.00 € | ||
| 500mg | 1,653.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
DS12881479
CAS:2373065-59-7
DS12881479 can be used in cancer research which is a potent and selective inhibitor of …
Formula:
C16H19N3OS
Purity:
100%
Color and Shape:
Liquid
Molecular weight:
301.41
Ref: TM-T60681
| 1mg | 96.00 € | ||
| 5mg | 236.00 € | ||
| 10mg | 354.00 € | ||
| 25mg | 637.00 € | ||
| 50mg | 857.00 € | ||
| 100mg | 1,126.00 € | ||
| 200mg | 1,537.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PERK-IN-3
CAS:1337532-08-7
PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).
Formula:
C22H16F2N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.38
Ref: TM-T12410
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
MNK1/2-IN-5
CAS:1426928-20-2
MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used …
Formula:
C17H16N4O2
Color and Shape:
Liquid
Molecular weight:
308.33
Ref: TM-T60733
| 1mg | 61.00 € | ||
| 5mg | 132.00 € | ||
| 10mg | 203.00 € | ||
| 25mg | 342.00 € | ||
| 50mg | 504.00 € | ||
| 100mg | 718.00 € | ||
| 500mg | 1,450.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
FR 167653
CAS:158876-66-5
FR 167653 sulfate, an orally active and selective inhibitor of p38 MAPK, is effective in …
Formula:
C24H20FN5O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
525.51
Ref: TM-T11327
| 5mg | 477.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
MCP110
CAS:521310-51-0
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used …
Formula:
C33H36N2O3
Purity:
97.18%
Color and Shape:
Oil
Molecular weight:
508.65
Ref: TM-T24437
| 1mg | 37.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 165.00 € | ||
| 25mg | 284.00 € | ||
| 50mg | 411.00 € | ||
| 100mg | 547.00 € | ||
| 500mg | 1,107.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
JAK2/FLT3-IN-1
CAS:2387765-27-5
Potent, orally active JAK2/FLT3-IN-1: Anti-cancer, dual JAK2/FLT3 inhibitor with low IC50s for JAK2/FLT3/JAK1/JAK3.
Formula:
C25H34FN7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
467.58
Ref: TM-T11707
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
AMG-548
CAS:864249-60-5
AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also …
Formula:
C29H27N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
461.56
Ref: TM-T10298L
| 10mg | 123.00 € | ||
| 25mg | 280.00 € | ||
| 100mg | 1,077.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
KRas G12C inhibitor 3
CAS:2206735-75-1
KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.
Formula:
C32H36ClN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
586.13
Ref: TM-T11778
| 25mg | 1,406.00 € | ||
| 50mg | 1,847.00 € | ||
| 100mg | 2,331.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
EO-1606
CAS:344457-87-0
EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies …
Formula:
C21H17ClFNO
Purity:
98.84% - 99.27%
Color and Shape:
Solid
Molecular weight:
353.82
Ref: TM-T31645
| 1mg | 273.00 € | ||
| 5mg | 673.00 € | ||
| 10mg | 920.00 € | ||
| 25mg | 1,416.00 € | ||
| 50mg | 1,845.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
BRAF inhibitor
CAS:918505-61-0
BRAF inhibitor is an inhibitor of B-Raf.
Formula:
C22H18F2N4O3S
Purity:
97.95% - 98.27%
Color and Shape:
Solid
Molecular weight:
456.47
Ref: TM-T10599
| 1mg | 46.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 387.00 € | ||
| 100mg | 552.00 € | ||
| 200mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
J30-8
CAS:2366255-71-0
J30-8 is a JNK3 inhibitor (IC50: 40 nM) with neuroprotective activity and can be used …
Formula:
C17H9ClFN3O2S
Purity:
99.90%
Color and Shape:
Solid
Molecular weight:
373.79
Ref: TM-T11702
| 1mg | 38.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
LY-2584702 hydrochloride
CAS:1082948-81-9
Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the …
Formula:
C21H20ClF4N7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
481.88
Ref: TM-T11900
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
