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MAPK

MAPK

MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.

Found 885 products of "MAPK"

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  • LY-2584702 hydrochloride
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    LY-2584702 hydrochloride

    CAS:
    <p>Ly-2584702 hydrochloride is a p70S6K selective ATP competitive inhibitor with IC50 of 4 nM.In the S6K1 enzyme assay, the IC50 of LY-2584702 was 2 nM.</p>
    Formula:C21H20ClF4N7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:481.88

    Ref: TM-T11900

  • MEK inhibitor
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    MEK inhibitor

    CAS:
    <p>MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.</p>
    Formula:C26H26N4O2
    Purity:97.48%
    Color and Shape:Solid
    Molecular weight:426.51

    Ref: TM-T11993

  • NSC-70220
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    NSC-70220

    CAS:
    <p>SOS1-IN-1 is an inhibitor of SOS1.</p>
    Formula:C22H15NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.36

    Ref: TM-T12978

  • MNK1/2-IN-5
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    MNK1/2-IN-5

    CAS:
    <p>MNK1/2-IN-5 is a potent and selective MNK1/2 inhibitor with anticancer activity and can be used to study solid tumors and hematological malignancies.</p>
    Formula:C17H16N4O2
    Purity:98.04%
    Color and Shape:Solid
    Molecular weight:308.33

    Ref: TM-T60733

  • MEK-IN-4
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    MEK-IN-4

    CAS:
    <p>MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.</p>
    Formula:C21H18N4OS
    Purity:98.35% - 99.16%
    Color and Shape:Solid
    Molecular weight:374.46

    Ref: TM-T28012

  • Nek2-IN-5
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    Nek2-IN-5

    CAS:
    <p>Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).</p>
    Formula:C15H12N6O
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:292.3

    Ref: TM-T28141

  • mSIRK
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    mSIRK

    CAS:
    <p>mSIRK (G-Protein βγ Binding Peptide) is an ERK1 and ERK2 dual activator that promotes alpha-subunit dissociation.</p>
    Formula:C93H150N20O25
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:1948.31

    Ref: TM-T80548

  • p38 MAPK Inhibitor
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    p38 MAPK Inhibitor

    CAS:
    <p>p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.</p>
    Formula:C20H13ClFN3O
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:365.79

    Ref: TM-T36010

  • BI-2852
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    BI-2852

    CAS:
    <p>BI-2852: nanomolar affinity KRAS switch I/II pocket inhibitor; blocks signaling, halts KRAS mutant cell growth.</p>
    Formula:C31H28N6O2
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:516.59

    Ref: TM-T10533

  • RMC-0331
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    RMC-0331

    CAS:
    <p>RMC-0331 (RM-023) is an oral SOS1 inhibitor with potential to block RAS activation and anticancer properties.</p>
    Formula:C22H25ClF3N5O3
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:499.91

    Ref: TM-T38170

  • ZINC12409120
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    ZINC12409120

    CAS:
    <p>ZINC12409120 (R-4584) is a selective ERK inhibitor.ZINC12409120 inhibits ERK with an IC50 of 5.0 μM.ZINC12409120 inhibits ERK activity by interfering with FGF23</p>
    Formula:C20H16N4O2
    Purity:99.71% - 99.95%
    Color and Shape:Solid
    Molecular weight:344.37

    Ref: TM-T61122

  • UR13870
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    UR13870

    CAS:
    <p>UR-13870 (Org 48762-0) is a p38 MAPK inhibitor that prevents bone damage in collagen-induced arthritis in mice.</p>
    Formula:C24H16F2N4
    Purity:99.18% - >99.99%
    Color and Shape:Solid
    Molecular weight:398.41

    Ref: TM-T29071

  • GSK2008607
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    GSK2008607

    CAS:
    <p>GSK2008607 is a potent B-RafV600E inhibitor with anticancer activity and can be used to study breast, colorectal, melanoma, thyroid, and ovarian cancers.</p>
    Formula:C31H28F3N7O3S2
    Purity:99.36%
    Color and Shape:Solid
    Molecular weight:667.72

    Ref: TM-T27454

  • SOS1-IN-15
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    SOS1-IN-15

    CAS:
    <p>SOS1-IN-15 is an orally active and potent SOS1 inhibitor with potential antitumor activity.SOS1-IN-15 is used in the study of colon cancer.</p>
    Formula:C28H27F3N6O2
    Purity:98.32%
    Color and Shape:Solid
    Molecular weight:536.548

    Ref: TM-T73164

  • JNK-IN-11
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    JNK-IN-11

    CAS:
    <p>JNK-IN-11 inhibits JNK1/2/3 (IC50: 2.2/21.4/1.8 μM); promising for Alzheimer's/Parkinson's research.</p>
    Formula:C12H11NO3S2
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:281.35

    Ref: TM-T60534

  • MKK7-COV-9
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    MKK7-COV-9

    CAS:
    MKK7-COV-9 is an MKK7 inhibitor that inhibits MKK7-induced protein-protein interactions and interrupts the activation of primary B cells in response to LPS.
    Formula:C18H16N4O2
    Purity:99.73% - 99.83%
    Color and Shape:Solid
    Molecular weight:320.35

    Ref: TM-T60857

  • (E)-GABAB receptor antagonist 1
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    (E)-GABAB receptor antagonist 1

    CAS:
    <p>(E)-GABAB antagonist 1 inhibits GABA IP3 production, with an IC50 of 37.9 μM and acts as a selective negative modulator.</p>
    Formula:C18H24O4
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:304.38

    Ref: TM-T11137

  • EO-1606
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    EO-1606

    CAS:
    <p>EO-1606 is a p38MAP kinase inhibitor with anti-inflammatory activity and may be used in studies of Alzheimer;s disease and dermatitis.</p>
    Formula:C21H17ClFNO
    Purity:98.28% - 98.84%
    Color and Shape:Solid
    Molecular weight:353.82

    Ref: TM-T31645

  • p38α inhibitor 4
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    p38α inhibitor 4

    CAS:
    p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.
    Formula:C14H7F6N3O
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:347.215

    Ref: TM-T78652

  • AKP-001
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    AKP-001

    CAS:
    AKP-001 is a selective inhibitor of MAPK of the p38α isoform and is used in the study of immune and digestive disorders.
    Formula:C21H13ClF2N4O2
    Purity:99.50% - 99.92%
    Color and Shape:Solid
    Molecular weight:426.8

    Ref: TM-T25015