MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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BAY-6035
CAS:2247890-13-5
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more …
Formula:
C22H28N4O3
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
396.48
Ref: TM-T36631
| 5mg | 52.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
4,10-Aromadendranediol
CAS:70051-38-6
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which …
Formula:
C15H26O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
238.371
Ref: TM-TN2995
| 5mg | 586.00 € | ||
| 1mL*10mM (DMSO) | 595.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Z16078526
CAS:852222-94-7
Z16078526 promotes Ucp1, p38 MAPK, lipolysis, thermogenic genes, and mitochondrial activity in mouse brown adipocytes.
Formula:
C18H17N3O4S
Purity:
98.93%
Color and Shape:
Liquid
Molecular weight:
371.41
Ref: TM-T77621
| 1mg | 52.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 387.00 € | ||
| 50mg | 573.00 € | ||
| 100mg | 820.00 € | ||
| 500mg | 1,661.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
JTP10-△-TATi TFA
JTP10-△-TATi TFA is a selective inhibitor of JNK2 peptide (IC50: 92 nM), exhibiting 10-fold selectivity …
Formula:
C120H213F3N48O28
Purity:
98%
Color and Shape:
Solid
Molecular weight:
2833.28
Ref: TM-TP2146
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
GNE-9815
CAS:2729996-45-4
GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) is a high kinase-selective
Formula:
C26H22FN5O2
Purity:
98.19% - 98.73%
Color and Shape:
Liquid
Molecular weight:
455.48
Ref: TM-T9585
| 1mg | 63.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 221.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 527.00 € | ||
| 100mg | 713.00 € | ||
| 500mg | 1,430.00 € | ||
| 1mL*10mM (DMSO) | 145.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
SB220025
CAS:165806-53-1
"SB220025 inhibits human p38 MAP kinase, reducing lipopolysaccharide-induced tumor necrosis factor."
Formula:
C18H19FN6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
338.38
Ref: TM-T28681
| 1mg | 281.00 € | ||
| 5mg | 691.00 € | ||
| 10mg | 944.00 € | ||
| 25mg | 1,435.00 € | ||
| 50mg | 1,894.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ras Inhibitory Peptide acetate
Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.
Formula:
C55H95N19O13
Purity:
96.63%
Color and Shape:
Liquid
Molecular weight:
1230.46
Ref: TM-T37422L
| 1mg | 187.00 € | ||
| 5mg | 420.00 € | ||
| 10mg | 620.00 € | ||
| 25mg | 947.00 € | ||
| 50mg | 1,324.00 € | ||
| 100mg | 1,784.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
B-Raf IN 2
CAS:2649372-20-1
B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It …
Formula:
C20H17F2N5O4S
Purity:
98.2%
Color and Shape:
Liquid
Molecular weight:
461.44
Ref: TM-T40284
| 1mg | 56.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 460.00 € | ||
| 100mg | 647.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Peonidin chloride
CAS:134-01-0
Peonidin chloride has antioxidant activity.
Formula:
C16H13ClO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.72
Ref: TM-TN1062
| 1mg | 153.00 € | ||
| 5mg | 568.00 € | ||
| 10mg | 1,063.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cearoin
CAS:52811-37-7
Cearoin suppresses inflammation, allergies, and NO production, and triggers autophagy and apoptosis in neuroblastomas via …
Formula:
C14H12O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
244.24
Ref: TM-TN3614
| 5mg | 1,363.00 € | ||
| 1mL*10mM (DMSO) | 1,693.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ref: TM-T200733
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Klotho-derived peptide 1 hydrochloride
Klotho-derived peptide 1 (KP1 human) hydrochloride inhibits the interaction between TGF-β and TGF-β receptor 2, …
Ref: TM-TP2892
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Manassantin B
CAS:88497-88-5
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity …
Formula:
C41H48O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
716.81
Ref: TM-TN4490
| 5mg | 255.00 € | ||
| 1mL*10mM (DMSO) | 227.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
2-Hydroxy-3-methylanthraquinone
CAS:17241-40-6
2-Hydroxy-3-methylanthraquinone triggers U937 cell apoptosis via p-p38MAPK, downregulates p-ERK1/2, and activates caspase-3.
Formula:
C15H10O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
238.24
Ref: TM-TN1211
| 5mg | 519.00 € | ||
| 1mL*10mM (DMSO) | 538.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Lupalbigenin
CAS:76754-24-0
Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.
Formula:
C25H26O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
406.47
Ref: TM-TN1889
| 1mg | 800.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Enniatin B1
CAS:19914-20-6
Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier and modulates ERK, NF-κB, and ACAT …
Formula:
C34H59N3O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
653.858
Ref: TM-T13680
| 1mg | 665.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Hydroxycitric acid
CAS:6205-14-7
(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of …
Formula:
C6H8O8
Color and Shape:
Solid
Molecular weight:
208.12
Ref: TM-TN1751
| 20mg | 65.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
PERK-IN-2
CAS:1337531-83-5
PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).
Formula:
C23H18F3N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
437.42
Ref: TM-T12409
| 2mg | 88.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Cerdulatinib hydrochloride
CAS:1369761-01-2
Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others …
Formula:
C20H28ClN7O3S
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
482
Ref: TM-T6104
| 2mg | 36.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 254.00 € | ||
| 200mg | 360.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
Bongkrekic acid
CAS:11076-19-0
Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia cepacia that …
Formula:
C28H38O7
Color and Shape:
Liquid
Molecular weight:
486.6
Ref: TM-T36067
| 1mg | 1,632.00 € |
Estimated delivery in United States, on Friday 20 Dec 2024
