MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Found 887 products of "MAPK"
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K-Ras G12C-IN-4
CAS:K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。Formula:C31H33ClN4O4Purity:99.00%Color and Shape:SolidMolecular weight:561.07Ref: TM-T11738
1mg71.00€5mg161.00€10mg236.00€25mg403.00€50mg532.00€100mg783.00€200mg1,054.00€1mL*10mM (DMSO)192.00€Regorafénib N-oxyde (M2)
CAS:Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.
Formula:C21H15ClF4N4O4Purity:98.03% - 98.26%Color and Shape:SolidMolecular weight:498.81KRAS G12C inhibitor 19
CAS:KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that shows anti-tumor activity in cellular assays, and the family inhibits tumor growth.Formula:C25H19ClF2N4O3SPurity:97.46%Color and Shape:SolidMolecular weight:528.96(R)-BI-2852
CAS:(R)-5-hydroxy isoindolin-1-one is an RAS protein inhibitor with antiproliferative and antitumor properties.Formula:C31H28N6O2Purity:97.80%Color and Shape:SoildMolecular weight:516.59MAP4K4-IN-3
CAS:MAP4K4-IN-3 (Compound 17) may be a viable target for antidiabetic agents, a serine/threonine protein kinase.Formula:C15H12ClN5Purity:98.07%Color and Shape:SolidMolecular weight:297.74Ref: TM-T11942
5mg44.00€10mg74.00€25mg144.00€50mg222.00€100mg354.00€200mg523.00€500mg797.00€1mL*10mM (DMSO)48.00€Tanzisertib
CAS:Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Formula:C21H23F3N6O2Purity:98.66% - 99.28%Color and Shape:SolidMolecular weight:448.44Ref: TM-T14895
1mg39.00€5mg93.00€10mg138.00€25mg268.00€50mg530.00€100mg705.00€200mg973.00€1mL*10mM (DMSO)92.00€SU3327
CAS:SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).Formula:C5H3N5O2S3Purity:98.39%Color and Shape:SolidMolecular weight:261.3ARS-1630
CAS:ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.Formula:C21H17ClF2N4O2Purity:97.78%Color and Shape:SolidMolecular weight:430.84Ref: TM-T10376
1mg38.00€5mg86.00€10mg112.00€25mg216.00€50mg310.00€100mg408.00€200mg580.00€1mL*10mM (DMSO)88.00€LUT014
CAS:LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.Formula:C27H19F3N8OPurity:99.03%Color and Shape:SolidMolecular weight:528.49MRTX-1257
CAS:MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% target engagement.Formula:C33H39N7O2Purity:97.3% - 99.07%Color and Shape:SolidMolecular weight:565.71Ref: TM-T16143
1mg60.00€2mg85.00€5mg124.00€10mg195.00€25mg351.00€50mg512.00€100mg743.00€200mg982.00€1mL*10mM (DMSO)166.00€BI-3406
CAS:BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.Formula:C23H25F3N4O3Purity:99.2% - 99.66%Color and Shape:SolidMolecular weight:462.46Ref: TM-T12979
1mg73.00€5mg160.00€10mg250.00€25mg464.00€50mg663.00€100mg919.00€500mg1,833.00€1mL*10mM (DMSO)170.00€INH154
CAS:INH154 is a potent Nek2 and Hec1 binding (INH) inhibitor with IC50s of 120 nM in MB468 cells and 200 nM in Hela cells for INH.Formula:C22H24N4OSPurity:99.95%Color and Shape:SolidMolecular weight:392.52Ref: TM-T11657
2mg34.00€5mg54.00€10mg82.00€25mg136.00€50mg203.00€100mg299.00€200mg416.00€1mL*10mM (DMSO)59.00€PF-3644022
CAS:PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), with anti-inflammatory properties. Also blocks MK3 and PRAK.Formula:C21H18N4OSPurity:98.13%Color and Shape:SolidMolecular weight:374.46Ref: TM-T16501
1mg37.00€5mg111.00€10mg202.00€25mg416.00€50mg620.00€100mg832.00€500mg1,663.00€1mL*10mM (DMSO)187.00€ACBI3
CAS:ACBI3 is a selective pan-KRAS degrader with anticancer activity that degrades oncogenic KRAS. ACBI3 inhibits the growth of most cancer cell lines driven by KRAS mutations.Formula:C50H62N14O6S2Purity:99.24%Color and Shape:SolidMolecular weight:1019.25ETC-206
CAS:ETC-206 is a selective inhibitor of MNK1 and MNK2 (IC50s: 64 nM and 86 nM).
Formula:C25H20N4O2Purity:99.72% - 99.79%Color and Shape:SolidMolecular weight:408.45MK2-IN-3 hydrate
CAS:MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)Formula:C21H18N4O2Purity:99.58%Color and Shape:SolidMolecular weight:358.39Ref: TM-T12058
1mg35.00€5mg64.00€10mg93.00€25mg180.00€50mg264.00€100mg369.00€200mg507.00€1mL*10mM (DMSO)78.00€Divarasib
CAS:Divarasib (GDC-6036), an investigational KRAS G12C inhibitor for solid tumors, has an IC50 of <0.01 μM.
Formula:C29H32ClF4N7O2Purity:99.237% - 99.83%Color and Shape:SolidMolecular weight:622.06CC-90003
CAS:CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.Formula:C22H21F3N6O2Purity:99.42%Color and Shape:SolidMolecular weight:458.44MRTX0902
CAS:MRTX0902 is an effective and high selective inhibitor of SOS1 with an IC50 of 46 nM and a Ki of 2 nM.Formula:C22H24N6OPurity:99.69%Color and Shape:SolidMolecular weight:388.47(R)-Ketorolac
CAS:(R)-Ketorolac ((+)-Ketorolac) is the R-enantiomer of Ketorolac, with potent analgesic activity.
Formula:C15H13NO3Purity:99.55%Color and Shape:SolidMolecular weight:255.27
