MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Ravoxertinib hydrochloride
CAS:2070009-58-2
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 …
Formula:
C21H19Cl2FN6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
477.32
Ref: TM-T15377
| 1mg | 46.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Alpinumisoflavone
CAS:34086-50-5
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and …
Formula:
C20H16O5
Color and Shape:
Solid
Molecular weight:
336.34
Ref: TM-TN3397
| 1mg | 154.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
Omtriptolide
CAS:195883-06-8
Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.
Formula:
C24H28O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
460.479
Ref: TM-T16390
| 1mg | 136.00 € |
Estimated delivery in United States, on Thursday 2 Jan 2025
CC-90003
CAS:1621999-82-3
CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.
Formula:
C22H21F3N6O2
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
458.44
Ref: TM-T14894
| 1mg | 46.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 541.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
MK2-IN-3 hydrate
CAS:1186648-22-5
MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 …
Formula:
C21H18N4O2
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
358.39
Ref: TM-T12058
| 1mg | 36.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 182.00 € | ||
| 50mg | 265.00 € | ||
| 100mg | 372.00 € | ||
| 200mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Tanzisertib
CAS:899805-25-5
Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, …
Formula:
C21H23F3N6O2
Purity:
98.66% - 99.28%
Color and Shape:
Solid
Molecular weight:
448.44
Ref: TM-T14895
| 1mg | 41.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 551.00 € | ||
| 100mg | 732.00 € | ||
| 200mg | 1,012.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
PF-3644022
CAS:1276121-88-0
PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), …
Formula:
C21H18N4OS
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
374.46
Ref: TM-T16501
| 1mg | 37.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 199.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 604.00 € | ||
| 100mg | 809.00 € | ||
| 500mg | 1,635.00 € | ||
| 1mL*10mM (DMSO) | 182.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Cephradine
CAS:38821-53-3
Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
Formula:
C16H19N3O4S
Purity:
98%
Color and Shape:
White Crystalline Powder; Polymorphic Solid
Molecular weight:
349.4
Ref: TM-T0199
| 100mg | 35.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
HI-TOPK-032
CAS:487020-03-1
HI-TOPK-032 is an effective and specific inhibitor of TOPK.
Formula:
C20H11N5OS
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
369.4
Ref: TM-T15481
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 320.00 € | ||
| 100mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
GW806742X
CAS:579515-63-2
GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.
Formula:
C25H22F3N7O4S
Purity:
98.30%
Color and Shape:
Solid
Molecular weight:
573.55
Ref: TM-T11520
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Methylthiouracil
CAS:56-04-2
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and …
Formula:
C5H6N2OS
Purity:
100% - 99.89%
Color and Shape:
Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)
Molecular weight:
142.18
Ref: TM-T0304
| 25mg | 52.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 85.00 € | ||
| 200mg | 130.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
K-Ras G12C-IN-4
CAS:2376328-55-9
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C..
Formula:
C31H33ClN4O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
561.07
Ref: TM-T11738
| 1mg | 72.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 797.00 € | ||
| 200mg | 1,072.00 € | ||
| 1mL*10mM (DMSO) | 196.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
LUT014
CAS:2274819-46-2
LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions …
Formula:
C27H19F3N8O
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
528.49
Ref: TM-T15794
| 1mg | 65.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 476.00 € | ||
| 100mg | 666.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
BI-3406
CAS:2230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless …
Formula:
C23H25F3N4O3
Purity:
99.20% - 99.66%
Color and Shape:
Solid
Molecular weight:
462.46
Ref: TM-T12979
| 1mg | 72.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 453.00 € | ||
| 50mg | 649.00 € | ||
| 100mg | 903.00 € | ||
| 500mg | 1,793.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
SU3327
CAS:40045-50-9
SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
Formula:
C5H3N5O2S3
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
261.3
Ref: TM-T13018
| 2mg | 43.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 310.00 € | ||
| 100mg | 467.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Urolithin B
CAS:1139-83-9
Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in …
Formula:
C13H8O3
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
212.2
Ref: TM-T13265
| 10mg | 46.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 120.00 € | ||
| 100mg | 187.00 € | ||
| 500mg | 464.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
LXH254
CAS:1800398-38-2
LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM …
Formula:
C25H25F3N4O4
Purity:
98.3% - 99.92%
Color and Shape:
Solid
Molecular weight:
502.49
Ref: TM-T11898
| 1mg | 52.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 355.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 675.00 € | ||
| 200mg | 927.00 € | ||
| 500mg | 1,413.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Regorafénib N-oxyde (M2)
CAS:835621-11-9
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.
Formula:
C21H15ClF4N4O4
Purity:
98.03% - 99.48%
Color and Shape:
Solid
Molecular weight:
498.81
Ref: TM-T10157
| 1mg | 44.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 318.00 € | ||
| 100mg | 461.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
AZD7624
CAS:1095004-78-6
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
Formula:
C27H30FN5O3
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
491.56
Ref: TM-T14381
| 1mg | 73.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 500.00 € | ||
| 50mg | 727.00 € | ||
| 100mg | 1,013.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
Honokiol
CAS:35354-74-6
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt …
Formula:
C18H18O2
Purity:
99.65% - 99.87%
Color and Shape:
Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter Taste
Molecular weight:
266.33
Ref: TM-T3001
| 50mg | 54.00 € | ||
| 100mg | 68.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
