MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Read more
Vacquinol-1
CAS:5428-80-8
Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
Formula:
C21H21ClN2O
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
352.86
Ref: TM-T7008
| 1mg | 182.00 € | ||
| 5mg | 399.00 € | ||
| 10mg | 593.00 € | ||
| 25mg | 920.00 € | ||
| 50mg | 1,268.00 € | ||
| 100mg | 1,706.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
SOS1-IN-11
CAS:2654741-64-5
SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM).
Formula:
C22H24F3N5O
Purity:
98.79%
Color and Shape:
Liquid
Molecular weight:
431.45
Ref: TM-T60029
| 1mg | 75.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 278.00 € | ||
| 25mg | 442.00 € | ||
| 50mg | 631.00 € | ||
| 100mg | 849.00 € | ||
| 1mL*10mM (DMSO) | 179.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
KRAS G12C inhibitor 19
CAS:2649788-46-3
KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that shows anti-tumor activity in …
Formula:
C25H19ClF2N4O3S
Purity:
98.31%
Color and Shape:
Liquid
Molecular weight:
528.96
Ref: TM-T40286
| 1mg | 89.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 532.00 € | ||
| 50mg | 765.00 € | ||
| 100mg | 1,050.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Lup-20(29)-en-28-oic acid
CAS:848784-85-0
Lup-20(29)-en-28-oic acid: Anticancer, blocks autophagy, boosts chemotherapeutics in HeLa cells. Pulsatilla saponin D: Has haemolytic …
Formula:
C47H76O17
Purity:
98%
Color and Shape:
Solid
Molecular weight:
913.1
Ref: TM-TN2118
| 5mg | 519.00 € | ||
| 1mL*10mM (DMSO) | 803.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
JNK-IN-13
CAS:345986-38-1
JNK-IN-13 is a JNK inhibitor that inhibits JNK3 and JNK2 and can be used in …
Formula:
C13H7ClN4S
Purity:
98.74%
Color and Shape:
Liquid
Molecular weight:
286.74
Ref: TM-T77694
| 10mg | 39.00 € | ||
| 25mg | 57.00 € | ||
| 50mg | 93.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
JNK-1-IN-2
"JNK-1-IN-2 (Compound c6) is a potent inhibitor of JNK-1 with an IC50 of 33.5 nM, …
Formula:
C16H20BrN5O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
378.27
Ref: TM-T79489
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Olomoucine
CAS:101622-51-9
Olomoucine hinders Cdk2, Cdc2, CDK5, ERK1, regulates the cell cycle, and fights melanoma; IC50s: 3-25 …
Formula:
C15H18N6O
Purity:
99.8%
Color and Shape:
White Crystalline Powder
Molecular weight:
298.34
Ref: TM-T21588
| 1mg | 66.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 455.00 € | ||
| 50mg | 662.00 € | ||
| 100mg | 846.00 € | ||
| 1mL*10mM (DMSO) | 136.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cajanin
CAS:32884-36-9
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage …
Formula:
C16H12O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
300.26
Ref: TM-TN1462
| 1mg | 584.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits …
Formula:
C51H65F4N9O9S2
Color and Shape:
Liquid
Molecular weight:
1088.24
Ref: TM-T200204
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
RMC-7977
CAS:2765082-12-8
RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with …
Formula:
C47H60N8O6S
Purity:
97.46% - 98.20%
Color and Shape:
Liquid
Molecular weight:
865.09
Ref: TM-T81263
| 1mg | 244.00 € | ||
| 5mg | 599.00 € | ||
| 10mg | 916.00 € | ||
| 25mg | 1,837.00 € | ||
| 50mg | 3,052.00 € | ||
| 100mg | 4,907.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
JNK-IN-14
JNK-IN-14 is a potent inhibitor of JNK with IC50 values of 1.81 nM for JNK1, …
Formula:
C27H31N5O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
521.63
Ref: TM-T79754
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
MHJ-627
MHJ-627, a potent inhibitor of ERK5 (MAPK7) with an IC50 value of 0.91 μM, enhances …
Formula:
C34H45BrN2O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
609.64
Ref: TM-T78796
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized …
Formula:
C31H30F5N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
627.61
Ref: TM-T79166
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PROTAC B-Raf degrader 1
CAS:2364367-27-9
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC …
Formula:
C36H37N5O12S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
763.77
Ref: TM-T12556
| 5mg | 407.00 € | ||
| 10mg | 651.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
STE-MEK1(13)
CAS:566872-15-9
STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes …
Formula:
C86H153N19O17S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1757.32
Ref: TM-T80543
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cyclorasin 9A5
CAS:1782098-79-6
Cyclorasin 9A5 is a cell-permeable, 11-residue cyclic peptide that orthosterically disrupts the Ras-Raf protein interaction, …
Formula:
C75H108FN25O13
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1586.82
Ref: TM-T82637
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
FAM49B (190-198) mouse
CAS:1588388-60-6
FAM49B (190-198) mouse represents a peptide fragment of the mitochondria-localized protein FAM49B, which is instrumental …
Formula:
C49H71N9O14S
Color and Shape:
Liquid
Molecular weight:
1042.2
Ref: TM-TP2834
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
ERK5-IN-5
CAS:2318792-30-0
ERK5-IN-5 is extracellular signal-regulated kinase 5 (ERK5) inhibitor with anticancer activity anticonvulsant activity inhibits A549 …
Formula:
C19H16ClN3O
Purity:
99.77%
Color and Shape:
Soild
Molecular weight:
337.8
Ref: TM-T77734
| 1mg | 85.00 € | ||
| 2mg | 111.00 € | ||
| 5mg | 179.00 € | ||
| 10mg | 277.00 € | ||
| 25mg | 558.00 € | ||
| 50mg | 910.00 € | ||
| 100mg | 1,443.00 € | ||
| 500mg | 2,801.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
JNK2-IN-1
JNK2-IN-1 (Compound J27), a selective JNK2 inhibitor with a dissociation constant (Kd) of 79.2 µM, …
Formula:
C30H26N4O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
522.55
Ref: TM-T78829
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
HPK1-IN-4
CAS:2739844-28-9
HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is …
Formula:
C23H26N6O3
Purity:
97.2%
Color and Shape:
Liquid
Molecular weight:
434.49
Ref: TM-T40350
| 1mg | 127.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 460.00 € | ||
| 25mg | 805.00 € | ||
| 50mg | 1,103.00 € | ||
| 100mg | 1,511.00 € | ||
| 1mL*10mM (DMSO) | 343.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
