MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Samidin
CAS:477-33-8
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 …
Formula:
C21H22O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
386.4
Ref: TM-TN4938
| 5mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 465.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
ZINC05007751
CAS:591239-68-8
ZINC05007751 inhibits NEK6 (IC50=3.4μM), selective for NEK1/6, inactive on NEK2/7/9.
Formula:
C18H12N2O3
Purity:
97.12%
Color and Shape:
Solid
Molecular weight:
304.3
Ref: TM-T9880
| 1mg | 56.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 810.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Cearoin
CAS:52811-37-7
Cearoin suppresses inflammation, allergies, and NO production, and triggers autophagy and apoptosis in neuroblastomas via …
Formula:
C14H12O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
244.24
Ref: TM-TN3614
| 5mg | 1,349.00 € | ||
| 1mL*10mM (DMSO) | 1,676.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Pan-RAS-IN-7
CAS:2642135-72-4
Pan-RAS-IN-7 (Compound D101) is a broad-spectrum RAS inhibitor used in the synthesis of antibody-drug conjugates …
Formula:
C59H76N8O8
Color and Shape:
Liquid
Molecular weight:
1025.28
Ref: TM-T201152
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
D-JNKI-1
CAS:1445179-97-4
D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.
Formula:
C164H286N66O40
Purity:
98%
Color and Shape:
Solid
Molecular weight:
3822.44
Ref: TM-T10937
| 50mg | 1,084.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BI1701963
BI1701963 is an orally effective inhibitor that targets the SOS1 and KRAS interaction, specifically inhibiting …
Formula:
C47H62N8O4S
Color and Shape:
Liquid
Molecular weight:
835.11
Ref: TM-T201333
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MRTF-A-IN-1
MRTF-A-IN-1 (compound 14) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces …
Formula:
C22H21N3
Color and Shape:
Liquid
Molecular weight:
327.42
Ref: TM-T201311
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
KRAS inhibitor-38
CAS:3059496-10-2
KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of …
Formula:
C53H68ClF2N9O8S
Color and Shape:
Liquid
Molecular weight:
1064.68
Ref: TM-T201113
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Broussonin A
CAS:73731-87-0
Broussonins A, new phytoalexins from mulberry, exhibit estrogenic effects, inhibit adipogenesis and reduce inflammatory iNOS …
Formula:
C16H18O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
258.317
Ref: TM-TN3539
| 5mg | 1,339.00 € | ||
| 1mL*10mM (DMSO) | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Quercetin 3,4'-dimethyl ether
CAS:33429-83-3
Quercetin 3,4'-dimethyl ether: anti-lipid peroxidation (IC50=0.3μM), anti-inflammatory, pro-apoptotic, anti-leukemia potential.
Formula:
C17H14O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
330.29
Ref: TM-TN4877
| 5mg | 513.00 € | ||
| 1mL*10mM (DMSO) | 522.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
KRAS G12D inhibitor 25
CAS:2768099-61-0
KRAS G12D inhibitor 25 (Compound 148) acts as an inhibitor for KRAS G12C and HSP90α, …
Formula:
C56H62ClN11O6
Color and Shape:
Liquid
Molecular weight:
1020.62
Ref: TM-T201006
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of …
Formula:
C33H39ClF2N6O3
Color and Shape:
Liquid
Molecular weight:
641.15
Ref: TM-T201044
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BRAFV600E-IN-1
BRAFV600E-IN-1 (compound 9S) is an inhibitor of BRAF. It exhibits significant apoptotic effects in cell …
Formula:
C23H16Cl3N5O4
Color and Shape:
Liquid
Molecular weight:
532.76
Ref: TM-T201205
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BAY-6035
CAS:2247890-13-5
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more …
Formula:
C22H28N4O3
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
396.48
Ref: TM-T36631
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 165.00 € | ||
| 1mL*10mM (DMSO) | 38.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
4,10-Aromadendranediol
CAS:70051-38-6
4,10-Aromadendranediol exhibits neurite outgrowth-inducing activity in neurons via activation of the ERK signaling pathway, which …
Formula:
C15H26O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
238.371
Ref: TM-TN2995
| 5mg | 590.00 € | ||
| 1mL*10mM (DMSO) | 598.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
QL-X-138 HCl
QL-X-138 HCl is a BTK/MNK dual kinase inhibitor with anticancer activity and anti-dengue virus 2 …
Formula:
C25H20ClN5O2
Purity:
98.89%
Color and Shape:
Soild
Molecular weight:
457.91
Ref: TM-T38960L
| 1mg | 185.00 € | ||
| 5mg | 459.00 € | ||
| 10mg | 657.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,415.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces …
Ref: TM-T200620
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Manassantin B
CAS:88497-88-5
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity …
Formula:
C41H48O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
716.81
Ref: TM-TN4490
| 5mg | 1,224.00 € | ||
| 1mL*10mM (DMSO) | 1,604.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BI-2865
CAS:2937327-93-8
BI-2865 is a non-covalent pan-KRAS inhibitor.Cost-effective and quality-assured.
Formula:
C23H27N7O2S
Purity:
99.19% - 99.39%
Color and Shape:
Soild
Molecular weight:
465.57
Ref: TM-T72062
| 1mg | 216.00 € | ||
| 5mg | 547.00 € | ||
| 10mg | 660.00 € | ||
| 25mg | 979.00 € | ||
| 50mg | 1,293.00 € | ||
| 100mg | 1,758.00 € | ||
| 1mL*10mM (DMSO) | 550.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
2-Hydroxy-3-methylanthraquinone
CAS:17241-40-6
2-Hydroxy-3-methylanthraquinone triggers U937 cell apoptosis via p-p38MAPK, downregulates p-ERK1/2, and activates caspase-3.
Formula:
C15H10O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
238.24
Ref: TM-TN1211
| 5mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 542.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
