MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Licochalcone D
CAS:144506-15-0
Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and …
Formula:
C21H22O5
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
354.4
Ref: TM-T4518
| 1mg | 94.00 € | ||
| 5mg | 222.00 € | ||
| 10mg | 322.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 763.00 € | ||
| 100mg | 1,011.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
(E/Z)-Necrosulfonamide
CAS:432531-71-0
(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.
Formula:
C18H15N5O6S2
Purity:
97.62% - 98%
Color and Shape:
Solid
Molecular weight:
461.47
Ref: TM-T7129
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 286.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
XMD17-109
CAS:1435488-37-1
XMD17-109 (ERK5-IN-1) is a new selective ERK-5 inhibitor (EC50: 4.2 uM, HEK293 cells).
Formula:
C36H46N8O3
Purity:
98.86% - 99.75%
Color and Shape:
Solid
Molecular weight:
638.8
Ref: TM-T1842
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 527.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
SB 239063
CAS:193551-21-2
SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 …
Formula:
C20H21FN4O2
Purity:
99.42% - 99.81%
Color and Shape:
Solid
Molecular weight:
368.4
Ref: TM-T6976
| 1mg | 50.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 156.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 495.00 € | ||
| 100mg | 712.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
K-Ras(G12C) Inhibitor 6
CAS:2060530-16-5
Irreversible K-Ras(G12C) inhibitor 6 fully modifies the protein at 10 μM after 24h in vitro.
Formula:
C17H22Cl2N2O3S
Purity:
100% - 97.01%
Color and Shape:
Solid
Molecular weight:
405.33
Ref: TM-T3725
| 1mg | 62.00 € | ||
| 2mg | 88.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 228.00 € | ||
| 25mg | 472.00 € | ||
| 50mg | 659.00 € | ||
| 100mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 131.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CMPD1
CAS:41179-33-3
CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM).
Formula:
C22H20FNO2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
349.4
Ref: TM-T14988
| 1mg | 37.00 € | ||
| 5mg | 103.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 437.00 € | ||
| 100mg | 677.00 € | ||
| 500mg | 1,576.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
TAK-715
CAS:303162-79-0
TAK-715 is a p38 MAPK inhibitor for p38α.
Formula:
C24H21N3OS
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
399.51
Ref: TM-T6150
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 317.00 € | ||
| 100mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
BIX02189
CAS:1094614-85-3
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM.
Formula:
C27H28N4O2
Purity:
98% - 99.86%
Color and Shape:
Solid
Molecular weight:
440.54
Ref: TM-T2416
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 85.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 634.00 € | ||
| 200mg | 885.00 € | ||
| 500mg | 1,291.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ML-191
CAS:931695-79-3
ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.
Formula:
C24H25N3O3
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
403.47
Ref: TM-T22996
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 515.00 € | ||
| 500mg | 1,091.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ASK1-IN-1
CAS:2411382-24-4
ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.
Formula:
C19H19N9O2
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
405.41
Ref: TM-T9697
| 1mg | 90.00 € | ||
| 5mg | 212.00 € | ||
| 10mg | 317.00 € | ||
| 25mg | 574.00 € | ||
| 50mg | 862.00 € | ||
| 100mg | 1,201.00 € | ||
| 1mL*10mM (DMSO) | 234.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
RAF709
CAS:1628838-42-5
RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for …
Formula:
C28H29F3N4O4
Purity:
99.43% - 99.83%
Color and Shape:
Solid
Molecular weight:
542.55
Ref: TM-T3711
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 130.00 € | ||
| 25mg | 256.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 618.00 € | ||
| 500mg | 1,287.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate
CAS:517870-17-6
methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate is a biochemical.
Formula:
C13H13NO5
Purity:
97.69%
Color and Shape:
Solid
Molecular weight:
263.25
Ref: TM-T8911
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 163.00 € | ||
| 200mg | 237.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Nardosinone
CAS:23720-80-1
Nardosinone inhibits H9c2 cell hypertrophy, protects neurons from OGD, and boosts neurite outgrowth by modifying …
Formula:
C15H22O3
Purity:
98.82% - 99%
Color and Shape:
Solid
Molecular weight:
250.33
Ref: TM-T6S1740
| 2mg | 36.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 202.00 € | ||
| 100mg | 296.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
2-Aminooctadecane-1,3,4-Triol
CAS:13552-11-9
2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product.
Formula:
C18H39NO3
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
317.51
Ref: TM-TN6814
| 1mg | 185.00 € | ||
| 5mg | 415.00 € | ||
| 10mg | 613.00 € | ||
| 25mg | 937.00 € | ||
| 50mg | 1,309.00 € | ||
| 100mg | 1,764.00 € | ||
| 500mg | 3,455.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
LJI308
CAS:1627709-94-7
LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 …
Formula:
C21H18F2N2O2
Purity:
98.86% - 99.73%
Color and Shape:
Solid
Molecular weight:
368.38
Ref: TM-T6878
| 1mg | 45.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 211.00 € | ||
| 50mg | 330.00 € | ||
| 100mg | 507.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
magnolin
CAS:31008-18-1
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo …
Formula:
C23H28O7
Purity:
98% - 99.57%
Color and Shape:
Solid
Molecular weight:
416.46
Ref: TM-T3857
| 20mg | 90.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
DB07268
CAS:929007-72-7
DB07268 is a potent and selective JNK1 inhibitor.
Formula:
C17H15N5O2
Purity:
98.2% - 98.91%
Color and Shape:
Solid
Molecular weight:
321.33
Ref: TM-T3200
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 121.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 618.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CK1-IN-1
CAS:1784751-20-7
CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.
Formula:
C24H15F2N3
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T5393
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 468.00 € | ||
| 100mg | 703.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Ro 5126766
CAS:946128-88-7
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 …
Formula:
C21H18FN5O5S
Purity:
98.13% - 98.3%
Color and Shape:
Solid
Molecular weight:
471.46
Ref: TM-T6971
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 515.00 € | ||
| 100mg | 744.00 € | ||
| 1mL*10mM (DMSO) | 118.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Rubrofusarin gentiobioside
CAS:24577-90-0
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) decreases the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity.
Formula:
C27H32O15
Purity:
99.75% - 99.91%
Color and Shape:
Solid
Molecular weight:
596.53
Ref: TM-TN2165
| 1mg | 53.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
