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  6. MAPK Signaling
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MEK

MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.

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products per page. 50 products on this category.

BrandProduct dataPurityPrice rangeEstimated delivery
Targetmol logo
Lidocaine Hydrochloride hydrate
REF: TM-T1144LCAS: 6108-05-0 		99.91%34.00 €~135.00 €Wed 04 Dec 24
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Lidocaine
REF: TM-T0468CAS: 137-58-6 		98.35% - 99.95%49.00 €Wed 04 Dec 24
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Lidocaine hydrochloride
REF: TM-T1144CAS: 73-78-9 		100% - 99.83%54.00 €Wed 04 Dec 24
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BAY-6035
REF: TM-T36631CAS: 2247890-13-5 		99.39%To inquireThu 05 Dec 24
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PD 198306
REF: TM-T21980CAS: 212631-61-3 		99.75%63.00 €~1,266.00 €Thu 05 Dec 24
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DS03090629
REF: TM-T200155		- - -To inquireThu 05 Dec 24
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Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
REF: TM-TMPK-00024		- - -802.00 €~5,185.00 €Tue 10 Dec 24
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Midkine Protein, Mouse, Recombinant (His)
REF: TM-TMPK-00812		- - -466.00 €~2,942.00 €Tue 10 Dec 24
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Midkine Protein, Human, Recombinant (His & Avi)
REF: TM-TMPK-00023		- - -468.00 €~2,955.00 €Tue 10 Dec 24
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GW284543
REF: TM-T7610CAS: 790186-68-4 		99.38%35.00 €~1,133.00 €Tue 10 Dec 24
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TAK-733
REF: TM-T6692CAS: 1035555-63-5 		98.31% - 99.53%55.00 €~521.00 €Wed 11 Dec 24
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Trametinib (DMSO solvate)
REF: TM-T5857CAS: 1187431-43-1 		100% - 99.71%48.00 €~114.00 €Wed 11 Dec 24
Targetmol logo
Binimetinib
REF: TM-T2508CAS: 606143-89-9 		100% - 99%41.00 €~149.00 €Wed 11 Dec 24
Targetmol logo
GW 284543 hydrochloride
REF: TM-T7742CAS: 179246-08-3 		≥95%56.00 €~935.00 €Wed 11 Dec 24
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Mirdametinib
REF: TM-T6189CAS: 391210-10-9 		99.18% - 99.63%54.00 €~878.00 €Wed 11 Dec 24
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GDC-0623
REF: TM-T6843CAS: 1168091-68-6 		98.27% - 98.95%52.00 €~609.00 €Wed 11 Dec 24
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AZD8330
REF: TM-T6083CAS: 869357-68-6 		98.72%38.00 €~299.00 €Wed 11 Dec 24
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Aurothiomalate sodium
REF: TM-T20168CAS: 12244-57-4 		99.66%52.00 €~523.00 €Wed 11 Dec 24
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SL327
REF: TM-T2708CAS: 305350-87-2 		100% - 99.74%36.00 €~900.00 €Wed 11 Dec 24
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PD184161
REF: TM-T21635CAS: 212631-67-9 		99.09%38.00 €~1,379.00 €Wed 11 Dec 24
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Lidocaine Hydrochloride hydrate
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Lidocaine Hydrochloride hydrate

CAS:6108-05-0
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
Formula:
C14H22N2O·HCl·H2O
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
288.82

Ref: TM-T1144L

1g135.00 €
50mg37.00 €
100mg49.00 €
500mg91.00 €
1mL*10mM (DMSO)34.00 €
Estimated delivery in United States, on Wednesday 4 Dec 2024
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Lidocaine
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Lidocaine

CAS:137-58-6
Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil …
Formula:
C14H22N2O
Purity:
98.35% - 99.95%
Color and Shape:
Needles From Benzene Or Alcohol Solid
Molecular weight:
234.34

Ref: TM-T0468

500mg49.00 €
Estimated delivery in United States, on Wednesday 4 Dec 2024
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Lidocaine hydrochloride
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Lidocaine hydrochloride

CAS:73-78-9
Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.
Formula:
C14H23ClN2O
Purity:
100% - 99.83%
Color and Shape:
White Crystal Powder
Molecular weight:
270.798

Ref: TM-T1144

500mg54.00 €
Estimated delivery in United States, on Wednesday 4 Dec 2024
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BAY-6035
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BAY-6035

CAS:2247890-13-5
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more …
Formula:
C22H28N4O3
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
396.48

Ref: TM-T36631

5mg52.00 €
10mg82.00 €
25mg151.00 €
50mg238.00 €
100mgTo inquire
1mL*10mM (DMSO)58.00 €
Estimated delivery in United States, on Thursday 5 Dec 2024
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PD 198306
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PD 198306

CAS:212631-61-3
PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.
Formula:
C18H16F3IN2O2
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
476.23

Ref: TM-T21980

1mg63.00 €
5mg136.00 €
10mg185.00 €
25mg324.00 €
50mg463.00 €
100mg642.00 €
500mg1,266.00 €
1mL*10mM (DMSO)159.00 €
Estimated delivery in United States, on Thursday 5 Dec 2024
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DS03090629

DS03090629, an orally active MEK inhibitor, functions by competitively inhibiting MEK activity in the presence …
Formula:
C25H26ClN5O2
Color and Shape:
Liquid
Molecular weight:
463.96

Ref: TM-T200155

10mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Thursday 5 Dec 2024
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Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
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Midkine Protein, Human, Recombinant (His & Avi), Biotinylated

Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive …
Color and Shape:
Liquid
Molecular weight:
16.46 kDa (predicted) same as Tris-Bis PAGE result.

Ref: TM-TMPK-00024

1mg5,185.00 €
100µg802.00 €
500µg3,098.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024
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Midkine Protein, Mouse, Recombinant (His)
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Midkine Protein, Mouse, Recombinant (His)

Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive …
Color and Shape:
Liquid
Molecular weight:
14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.

Ref: TM-TMPK-00812

1mg2,942.00 €
100µg466.00 €
500µg1,756.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024
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Midkine Protein, Human, Recombinant (His & Avi)
Targetmol logo
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Midkine Protein, Human, Recombinant (His & Avi)

Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive …
Color and Shape:
Liquid
Molecular weight:
16.46 kDa (predicted) same as Tris-Bis PAGE result.

Ref: TM-TMPK-00023

1mg2,955.00 €
100µg468.00 €
500µg1,764.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024
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GW284543
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GW284543

CAS:790186-68-4
GW284543 (UNC10225170) is a selective inhibitor of MEK5 .
Formula:
C23H20N2O3
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
372.42

Ref: TM-T7610

1mg35.00 €
5mg73.00 €
10mg102.00 €
25mg182.00 €
50mg304.00 €
100mg489.00 €
1mL*10mM (DMSO)82.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024
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TAK-733
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TAK-733

CAS:1035555-63-5
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic …
Formula:
C17H15F2IN4O4
Purity:
98.31% - 99.53%
Color and Shape:
Solid
Molecular weight:
504.23

Ref: TM-T6692

1mg55.00 €
2mg79.00 €
5mg112.00 €
10mg196.00 €
25mg352.00 €
50mg521.00 €
1mL*10mM (DMSO)132.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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Trametinib (DMSO solvate)
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Trametinib (DMSO solvate)

CAS:1187431-43-1
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that …
Formula:
C28H29FIN5O5S
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
693.53

Ref: TM-T5857

10mg48.00 €
25mg58.00 €
50mg62.00 €
100mg89.00 €
200mg114.00 €
1mL*10mM (DMSO)55.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
+ info
discount label
Binimetinib
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Binimetinib

CAS:606143-89-9
Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has …
Formula:
C17H15BrF2N4O3
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
441.23

Ref: TM-T2508

5mg41.00 €
10mg62.00 €
25mg74.00 €
50mg86.00 €
100mg94.00 €
200mg149.00 €
1mL*10mM (DMSO)69.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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GW 284543 hydrochloride
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GW 284543 hydrochloride

CAS:179246-08-3
GW 284543 hydrochloride is a selective inhibitor of MEK5 .
Formula:
C23H21ClN2O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
408.87

Ref: TM-T7742

1mg56.00 €
2mg73.00 €
5mg94.00 €
10mg168.00 €
25mg313.00 €
50mg532.00 €
100mg728.00 €
200mg935.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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Mirdametinib
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Mirdametinib

CAS:391210-10-9
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.
Formula:
C16H14F3IN2O4
Purity:
99.18% - 99.63%
Color and Shape:
White Powder
Molecular weight:
482.19

Ref: TM-T6189

1g878.00 €
5mg56.00 €
10mg78.00 €
25mg129.00 €
50mg177.00 €
100mg274.00 €
200mg405.00 €
500mg647.00 €
1mL*10mM (DMSO)55.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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GDC-0623
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GDC-0623

CAS:1168091-68-6
GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. …
Formula:
C16H14FIN4O3
Purity:
98.27% - 98.95%
Color and Shape:
Solid
Molecular weight:
456.21

Ref: TM-T6843

1mg52.00 €
2mg72.00 €
5mg118.00 €
10mg183.00 €
25mg279.00 €
50mg366.00 €
100mg609.00 €
1mL*10mM (DMSO)120.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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discount label
AZD8330
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AZD8330

CAS:869357-68-6
AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 …
Formula:
C16H17FIN3O4
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
461.23

Ref: TM-T6083

1mg38.00 €
5mg79.00 €
10mg119.00 €
25mg198.00 €
50mg299.00 €
1mL*10mM (DMSO)80.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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Aurothiomalate sodium
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Aurothiomalate sodium

CAS:12244-57-4
Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.
Formula:
C4H6O4S·Au·xNa
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
390.07

Ref: TM-T20168

5mg52.00 €
10mg80.00 €
25mg145.00 €
50mg217.00 €
100mg354.00 €
200mg523.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
+ info
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SL327
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SL327

CAS:305350-87-2
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to …
Formula:
C16H12F3N3S
Purity:
100% - 99.74%
Color and Shape:
Solid
Molecular weight:
335.35

Ref: TM-T2708

5mg36.00 €
10mg46.00 €
25mg68.00 €
50mg93.00 €
100mg155.00 €
1mL*10mM (DMSO)40.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
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PD184161
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PD184161

CAS:212631-67-9
PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) …
Formula:
C17H13BrClF2IN2O2
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
557.56

Ref: TM-T21635

1mg38.00 €
2mg52.00 €
5mg78.00 €
10mg124.00 €
25mg268.00 €
50mg446.00 €
100mg641.00 €
200mg920.00 €
500mg1,379.00 €
Estimated delivery in United States, on Wednesday 11 Dec 2024
+ info
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