MEK
MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.
Read more
Lidocaine hydrochloride
CAS:73-78-9
Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.
Formula:
C14H23ClN2O
Purity:
99.81% - 99.92%
Color and Shape:
White Crystal Powder
Molecular weight:
270.798
Ref: TM-T1144
| 500mg | 49.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
Lidocaine
CAS:137-58-6
Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil …
Formula:
C14H22N2O
Purity:
98.35% - 99.95%
Color and Shape:
Needles From Benzene Or Alcohol Solid
Molecular weight:
234.34
Ref: TM-T0468
| 500mg | 49.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
Lidocaine Hydrochloride hydrate
CAS:6108-05-0
Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.
Formula:
C14H22N2O·HCl·H2O
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
288.82
Ref: TM-T1144L
| 1g | 139.00 € | ||
| 50mg | 38.00 € | ||
| 100mg | 49.00 € | ||
| 500mg | 95.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Thursday 8 May 2025
BAY-6035
CAS:2247890-13-5
BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more …
Formula:
C22H28N4O3
Purity:
99.39%
Color and Shape:
Liquid
Molecular weight:
396.48
Ref: TM-T36631
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 165.00 € | ||
| 1mL*10mM (DMSO) | 38.00 € |
Estimated delivery in United States, on Friday 9 May 2025
PD 198306
CAS:212631-61-3
PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.
Formula:
C18H16F3IN2O2
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
476.23
Ref: TM-T21980
| 1mg | 64.00 € | ||
| 5mg | 138.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 655.00 € | ||
| 500mg | 1,293.00 € | ||
| 1mL*10mM (DMSO) | 160.00 € |
Estimated delivery in United States, on Friday 9 May 2025
MEK ligand-2
CAS:212631-56-6
MEK ligand-2, a ligand for the target protein for PROTAC (Ligand for Target Protein for …
Formula:
C13H8F3IN2O2
Color and Shape:
Liquid
Molecular weight:
408.12
Ref: TM-T201410
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
DS03090629
DS03090629, an orally active MEK inhibitor, functions by competitively inhibiting MEK activity in the presence …
Formula:
C25H26ClN5O2
Color and Shape:
Solid
Molecular weight:
463.96
Ref: TM-T200155
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 9 May 2025
Midkine Protein, Human, Recombinant (His & Avi)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive …
Color and Shape:
Lyophilized Powder
Molecular weight:
16.46 kDa (predicted) same as Tris-Bis PAGE result.
Ref: TM-TMPK-00023
| 1mg | 3,039.00 € | ||
| 100µg | 478.00 € | ||
| 500µg | 1,813.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
GW284543
CAS:790186-68-4
GW284543 (UNC10225170) is a selective inhibitor of MEK5 .
Formula:
C23H20N2O3
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
372.42
Ref: TM-T7610
| 1mg | 35.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
Midkine Protein, Mouse, Recombinant (His)
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive …
Color and Shape:
Lyophilized Powder
Molecular weight:
14.03 kDa (predicted). The protein migrates to 17-20 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00812
| 1mg | 3,039.00 € | ||
| 100µg | 478.00 € | ||
| 500µg | 1,813.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive …
Color and Shape:
Lyophilized Powder
Molecular weight:
16.46 kDa (predicted) same as Tris-Bis PAGE result.
Ref: TM-TMPK-00024
| 1mg | 5,333.00 € | ||
| 100µg | 824.00 € | ||
| 500µg | 3,185.00 € |
Estimated delivery in United States, on Tuesday 13 May 2025
Trametinib (DMSO solvate)
CAS:1187431-43-1
Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that …
Formula:
C28H29FIN5O5S
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
693.53
Ref: TM-T5857
| 10mg | 48.00 € | ||
| 25mg | 59.00 € | ||
| 50mg | 63.00 € | ||
| 100mg | 89.00 € | ||
| 200mg | 115.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
Binimetinib
CAS:606143-89-9
Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has …
Formula:
C17H15BrF2N4O3
Purity:
100% - 99%
Color and Shape:
Solid
Molecular weight:
441.23
Ref: TM-T2508
| 5mg | 42.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 96.00 € | ||
| 200mg | 153.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
GW 284543 hydrochloride
CAS:179246-08-3
GW 284543 hydrochloride is a selective inhibitor of MEK5 .
Formula:
C23H21ClN2O3
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
408.87
Ref: TM-T7742
| 1mg | 56.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 316.00 € | ||
| 50mg | 538.00 € | ||
| 100mg | 737.00 € | ||
| 200mg | 948.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
Mirdametinib
CAS:391210-10-9
Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.
Formula:
C16H14F3IN2O4
Purity:
99.18% - 99.63%
Color and Shape:
White Powder
Molecular weight:
482.19
Ref: TM-T6189
| 1g | 898.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 175.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 406.00 € | ||
| 500mg | 662.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
GDC-0623
CAS:1168091-68-6
GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. …
Formula:
C16H14FIN4O3
Purity:
98.27% - 98.95%
Color and Shape:
Solid
Molecular weight:
456.21
Ref: TM-T6843
| 1mg | 52.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 612.00 € | ||
| 1mL*10mM (DMSO) | 119.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
AZD8330
CAS:869357-68-6
AZD8330 (ARRY-704) is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 …
Formula:
C16H17FIN3O4
Purity:
98.72%
Color and Shape:
Solid
Molecular weight:
461.23
Ref: TM-T6083
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 305.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
Aurothiomalate sodium
CAS:74916-57-7
Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.
Formula:
C4H3AuNa2O4S
Purity:
99.66%
Color and Shape:
Soild
Molecular weight:
390.07
Ref: TM-T20168
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 216.00 € | ||
| 100mg | 354.00 € | ||
| 200mg | 522.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
SL327
CAS:305350-87-2
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to …
Formula:
C16H12F3N3S
Purity:
100% - 99.91%
Color and Shape:
Solid
Molecular weight:
335.35
Ref: TM-T2708
| 5mg | 37.00 € | ||
| 10mg | 48.00 € | ||
| 25mg | 70.00 € | ||
| 50mg | 97.00 € | ||
| 100mg | 160.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
PD184161
CAS:212631-67-9
PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) …
Formula:
C17H13BrClF2IN2O2
Purity:
99.40%
Color and Shape:
Solid
Molecular weight:
557.56
Ref: TM-T21635
| 1mg | 38.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 454.00 € | ||
| 100mg | 653.00 € | ||
| 200mg | 938.00 € | ||
| 500mg | 1,406.00 € |
Estimated delivery in United States, on Thursday 15 May 2025
