MEK
MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.
Found 75 products for "MEK".
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PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purity:99.40%Color and Shape:SolidMolecular weight:557.556BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:Yellow SolidMolecular weight:464.5582U0126-EtOH
CAS:U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!Formula:C20H22N6OS2Purity:99.72% - 99.88%Color and Shape:SolidMolecular weight:426.558trans-Zeatin
CAS:trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrientFormula:C10H13N5OPurity:97.13% - 98.96%Color and Shape:White SolidMolecular weight:219.2431Cobimetinib
CAS:Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C21H21F3IN3O2Purity:98% - 99.96%Color and Shape:White SolidMolecular weight:531.31U0126
CAS:U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.Formula:C18H16N6S2Purity:99.61%Color and Shape:White SolidMolecular weight:380.49APS-2-79 hydrochloride
CAS:APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization.Formula:C23H22ClN3O3Purity:98.64% - 99.55%Color and Shape:SolidMolecular weight:423.892Isorhamnetin
CAS:Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.Formula:C16H12O7Purity:99.20% - >99.99%Color and Shape:Yellow SolidMolecular weight:316.2623PD318088
CAS:PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-Formula:C16H13BrF3IN2O4Purity:99.60%Color and Shape:White SolidMolecular weight:561.089Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39GW284543
CAS:GW284543 (UNC10225170) is a selective inhibitor of MEK5 .Formula:C23H20N2O3Purity:99.75%Color and Shape:SolidMolecular weight:372.4165Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Formula:C14H23ClN2OPurity:99.00% - 99.92%Color and Shape:SolidMolecular weight:270.798PD 334581
CAS:MEK1 inhibitorFormula:C20H19F3IN5O2Purity:98%Color and Shape:SolidMolecular weight:545.3Balamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Formula:C30H32ClN7OSPurity:99.84%Color and Shape:White SolidMolecular weight:574.139MEK inhibitor
CAS:MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.Formula:C26H26N4O2Purity:97.48%Color and Shape:SolidMolecular weight:426.5102(R)-PD 0325901CL
CAS:(R)-PD 0325901CL, a PD 0325901CL isomer, is a MEK inhibitor used in cancer research, effective against cancer cells in vitro and in vivo.Formula:C16H14ClF2IN2O4Color and Shape:SolidMolecular weight:498.65JTP-70902
CAS:JTP-70902 is a protein kinase inhibitor with antineoplastic activity.Formula:C24H21BrFN5O5SColor and Shape:SolidMolecular weight:590.42MEK-IN-4
CAS:MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.Formula:C21H18N4OSPurity:98.35% - 98.38%Color and Shape:White SolidMolecular weight:374.459MEK-IN-1
CAS:MEK-IN-1 is a MEK inhibitor.Formula:C24H20N4O4Purity:98%Color and Shape:SolidMolecular weight:428.44(2Z,3Z)-U0126
CAS:U0126 selectively inhibits MEK1/2, blocks MAPK/ERK signaling, and suppresses Ki-ras-induced cell growth, with IC50s of 72 nM and 58 nM for MEK1/2.Formula:C18H16N6S2Color and Shape:SolidMolecular weight:380.49
