MEK
MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.
Found 72 products of "MEK"
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SL327
CAS:<p>SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.</p>Formula:C16H12F3N3SPurity:97.98% - >99.99%Color and Shape:SolidMolecular weight:335.35PD184161
CAS:<p>PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].</p>Formula:C17H13BrClF2IN2O2Purity:99.40%Color and Shape:SolidMolecular weight:557.56BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56U0126-EtOH
CAS:<p>U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!</p>Formula:C18H16N6S2·C2H6OPurity:99.72% - 99.88%Color and Shape:SolidMolecular weight:426.6trans-Zeatin
CAS:<p>trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient</p>Formula:C10H13N5OPurity:97.13% - 98.96%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:219.24Cobimetinib
CAS:<p>Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Formula:C21H21F3IN3O2Purity:98% - 99.61%Color and Shape:SolidMolecular weight:531.31U0126
CAS:<p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>Formula:C18H16N6S2Purity:99.61%Color and Shape:White SolidMolecular weight:380.49APS-2-79 hydrochloride
CAS:<p>APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization.</p>Formula:C23H21N3O3·HClPurity:98.64% - 99.55%Color and Shape:SolidMolecular weight:423.89Isorhamnetin
CAS:<p>Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.</p>Formula:C16H12O7Purity:99.20% - >99.99%Color and Shape:SolidMolecular weight:316.26PD318088
CAS:<p>PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-</p>Formula:C16H13BrF3IN2O4Purity:99.81%Color and Shape:SolidMolecular weight:561.09Trametinib
CAS:<p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.</p>Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39RO4987655
CAS:<p>RO4987655 (RG7167) is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).</p>Formula:C20H19F3IN3O5Purity:98.21%Color and Shape:SolidMolecular weight:565.28GW284543
CAS:<p>GW284543 (UNC10225170) is a selective inhibitor of MEK5 .</p>Formula:C23H20N2O3Purity:99.75%Color and Shape:SolidMolecular weight:372.42Trametiglue
CAS:<p>Trametiglue, a potent Trametinib derivative, selectively targets KSR-MEK and RAF-MEK through unique binding.</p>Formula:C25H24FIN6O5SColor and Shape:SolidMolecular weight:666.46Avutometinib potassium
CAS:<p>Avutometinib potassium, a MEKi, blocks Delta and Omicron infection in airway cells, potentially lessening disease severity.</p>Formula:C21H17FKN5O5SColor and Shape:SolidMolecular weight:509.55PD 334581
CAS:<p>MEK1 inhibitor</p>Formula:C20H19F3IN5O2Purity:98%Color and Shape:SolidMolecular weight:545.3MEK inhibitor
CAS:<p>MEK inhibitor is a MEK receptor and cell cycle protein/CDK complex inhibitor with antitumor activity that can be used to study tumor cell proliferation.</p>Formula:C26H26N4O2Purity:97.48%Color and Shape:SolidMolecular weight:426.51JTP-70902
CAS:<p>JTP-70902 is a protein kinase inhibitor with antineoplastic activity.</p>Formula:C24H21BrFN5O5SColor and Shape:SolidMolecular weight:590.42MEK-IN-1
CAS:<p>MEK-IN-1 is a MEK inhibitor.</p>Formula:C24H20N4O4Purity:98%Color and Shape:SolidMolecular weight:428.44MEK-IN-4
CAS:<p>MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.</p>Formula:C21H18N4OSPurity:98.35% - 99.16%Color and Shape:SolidMolecular weight:374.46
