MEK
MEK is a dual-specificity kinase that plays a central role in the MAPK/ERK signaling pathway by activating ERK through phosphorylation. MEK signaling is crucial for regulating cell growth, survival, and differentiation. Aberrant MEK activity has been implicated in various cancers and developmental disorders, making it an important therapeutic target. At CymitQuimica, we provide a variety of MEK inhibitors and modulators to support your research in oncology, cell signaling, and therapeutic development.
Found 74 products for "MEK".
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BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:Yellow SolidMolecular weight:464.56U0126-EtOH
CAS:U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!Formula:C18H16N6S2·C2H6OPurity:99.72% - 99.88%Color and Shape:SolidMolecular weight:426.6trans-Zeatin
CAS:trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrientFormula:C10H13N5OPurity:97.13% - 98.96%Color and Shape:White SolidMolecular weight:219.24Ref: TM-TMS2181
1mL*10mM (DMSO)33.00€10mg37.00€25mg52.00€50mg66.00€100mg96.00€200mg128.00€500mg205.00€Cobimetinib
CAS:Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.Formula:C21H21F3IN3O2Purity:98% - 99.96%Color and Shape:White SolidMolecular weight:531.31Ref: TM-T3623
500mgTo inquire1mg38.00€2mg49.00€5mg80.00€10mg90.00€1mL*10mM (DMSO)94.00€25mg170.00€50mg261.00€100mg429.00€U0126
CAS:U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.Formula:C18H16N6S2Purity:99.61%Color and Shape:White SolidMolecular weight:380.49APS-2-79 hydrochloride
CAS:APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization.Formula:C23H21N3O3·HClPurity:98.64% - 99.55%Color and Shape:SolidMolecular weight:423.89Isorhamnetin
CAS:Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.Formula:C16H12O7Purity:99.20% - >99.99%Color and Shape:Yellow SolidMolecular weight:316.26Ref: TM-T2836
1mg38.00€2mg49.00€5mg78.00€1mL*10mM (DMSO)81.00€10mg113.00€25mg222.00€50mg371.00€100mg532.00€PD318088
CAS:PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor, binding simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-Formula:C16H13BrF3IN2O4Purity:99.60%Color and Shape:White SolidMolecular weight:561.09RO4987655
CAS:RO4987655 (RG7167) is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).Formula:C20H19F3IN3O5Purity:98.21%Color and Shape:White SolidMolecular weight:565.28GW284543
CAS:GW284543 (UNC10225170) is a selective inhibitor of MEK5 .Formula:C23H20N2O3Purity:99.75%Color and Shape:SolidMolecular weight:372.42Trametiglue
CAS:Trametiglue, a potent Trametinib derivative, selectively targets KSR-MEK and RAF-MEK through unique binding.Formula:C25H24FIN6O5SColor and Shape:SolidMolecular weight:666.46BAY-846
CAS:BAY-846: allosteric MEK inhibitor, long-lasting, highly bioavailable, low brain entry, effective in K-Ras A549 model.Formula:C19H13F4IN4O4SColor and Shape:SolidMolecular weight:596.29Balamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Formula:C30H32ClN7OSPurity:99.84%Color and Shape:White SolidMolecular weight:574.14(2Z,3Z)-U0126
CAS:U0126 selectively inhibits MEK1/2, blocks MAPK/ERK signaling, and suppresses Ki-ras-induced cell growth, with IC50s of 72 nM and 58 nM for MEK1/2.Formula:C18H16N6S2Color and Shape:SolidMolecular weight:380.49Avutometinib potassium
CAS:Avutometinib potassium, a MEKi, blocks Delta and Omicron infection in airway cells, potentially lessening disease severity.Formula:C21H17FKN5O5SColor and Shape:SolidMolecular weight:509.55(R)-PD 0325901CL
CAS:(R)-PD 0325901CL, a PD 0325901CL isomer, is a MEK inhibitor used in cancer research, effective against cancer cells in vitro and in vivo.Formula:C16H14ClF2IN2O4Color and Shape:SolidMolecular weight:498.65JTP-70902
CAS:JTP-70902 is a protein kinase inhibitor with antineoplastic activity.Formula:C24H21BrFN5O5SColor and Shape:SolidMolecular weight:590.42PD 334581
CAS:MEK1 inhibitorFormula:C20H19F3IN5O2Purity:98%Color and Shape:SolidMolecular weight:545.3MEK-IN-4
CAS:MEK-IN-4 is a MEK inhibitor that can be used to study inflammatory diseases and cancer.Formula:C21H18N4OSPurity:98.35% - 98.38%Color and Shape:White SolidMolecular weight:374.46MEK-IN-1
CAS:MEK-IN-1 is a MEK inhibitor.Formula:C24H20N4O4Purity:98%Color and Shape:SolidMolecular weight:428.44
