MLK
MLKs are a group of kinases that can activate multiple MAPK pathways, including JNK and p38, by phosphorylating upstream MAP kinase kinases (MAP2Ks). MLKs are involved in cellular responses to stress, apoptosis, and neuroinflammation. Dysregulation of MLK activity is associated with neurodegenerative diseases and certain cancers. At CymitQuimica, we offer a range of high-quality MLK modulators to support your research in neurobiology, stress response, and signal transduction.
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GW806742X
CAS:579515-63-2
GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.
Formula:
C25H22F3N7O4S
Purity:
98.30%
Color and Shape:
Solid
Molecular weight:
573.55
Ref: TM-T11520
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
MLKL-IN-2
CAS:899759-16-1
MLKL-IN-2 is an MLKL inhibitor with potential tumorigenic activity for the study of cellular necrosis-related …
Formula:
C26H25N5O
Purity:
98.61%
Color and Shape:
Solid
Molecular weight:
423.51
Ref: TM-T41027
| 1mg | 90.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 631.00 € | ||
| 50mg | 993.00 € | ||
| 100mg | 1,532.00 € | ||
| 200mg | 2,070.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AZ7550 trimesylate salt
CAS:2319837-99-3
AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 inhibits IGF1R activity …
Formula:
C30H43N7O11S3
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
773.9
Ref: TM-T13564L2
| 1mg | 147.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Cerdulatinib hydrochloride
CAS:1369761-01-2
Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others …
Formula:
C20H28ClN7O3S
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
482
Ref: TM-T6104
| 2mg | 36.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 115.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 254.00 € | ||
| 200mg | 360.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(E/Z)-Necrosulfonamide
CAS:432531-71-0
(E/Z)-Necrosulfonamide is a novel inhibitor of MLKL.
Formula:
C18H15N5O6S2
Purity:
97.62% - 98%
Color and Shape:
Solid
Molecular weight:
461.47
Ref: TM-T7129
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 116.00 € | ||
| 50mg | 191.00 € | ||
| 100mg | 286.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Necrosulfonamide
CAS:1360614-48-7
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis.
Formula:
C18H15N5O6S2
Purity:
98.85% - 99.49%
Color and Shape:
Solid
Molecular weight:
461.47
Ref: TM-T6904
| 5mg | 56.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 211.00 € | ||
| 100mg | 370.00 € | ||
| 500mg | 875.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
PRT062607 hydrochloride
CAS:1370261-97-4
PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold …
Formula:
C19H23N9O·HCl
Purity:
97.11% - 99.93%
Color and Shape:
Solid
Molecular weight:
429.91
Ref: TM-T2696
| 1mg | 61.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 327.00 € | ||
| 50mg | 500.00 € | ||
| 200mg | 946.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
LY-364947
CAS:396129-53-6
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
Formula:
C17H12N4
Purity:
99.41% - 99.96%
Color and Shape:
Solid
Molecular weight:
272.3
Ref: TM-T2048
| 5mg | 69.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 254.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 547.00 € | ||
| 500mg | 858.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
AZ7550
CAS:1421373-99-0
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:
C27H31N7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
485.58
Ref: TM-T13564
| 1mg | 129.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 417.00 € | ||
| 25mg | 689.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,287.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
IM-54
CAS:861891-50-1
IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.
Formula:
C19H23N3O2
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
325.4
Ref: TM-T24160
| 1mg | 57.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 181.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 653.00 € | ||
| 500mg | 1,328.00 € |
Estimated delivery in United States, on Monday 24 Feb 2025
