Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
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ARS-1630
CAS:1698055-86-5
ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.
Formula:
C21H17ClF2N4O2
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
430.84
Ref: TM-T10376
| 1mg | 51.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 164.00 € | ||
| 25mg | 314.00 € | ||
| 50mg | 451.00 € | ||
| 100mg | 593.00 € | ||
| 1mL*10mM (DMSO) | 129.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MRTX-1257
CAS:2206736-04-9
MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% …
Formula:
C33H39N7O2
Purity:
96.59% - 99.07%
Color and Shape:
Solid
Molecular weight:
565.71
Ref: TM-T16143
| 1mg | 63.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 217.00 € | ||
| 25mg | 367.00 € | ||
| 50mg | 550.00 € | ||
| 100mg | 786.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MBQ-167
CAS:2097938-73-1
MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 …
Formula:
C22H18N4
Purity:
98.07% - 98.74%
Color and Shape:
Solid
Molecular weight:
338.41
Ref: TM-T16021
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BI-3406
CAS:2230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless …
Formula:
C23H25F3N4O3
Purity:
99.20% - 99.66%
Color and Shape:
Solid
Molecular weight:
462.46
Ref: TM-T12979
| 1mg | 72.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 453.00 € | ||
| 50mg | 649.00 € | ||
| 100mg | 903.00 € | ||
| 500mg | 1,793.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
HJC0197
CAS:1383539-73-8
HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.
Formula:
C19H21N3OS
Purity:
98.05%
Color and Shape:
Solid
Molecular weight:
339.45
Ref: TM-T15485
| 2mg | 37.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 272.00 € | ||
| 200mg | 411.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Ketoconazole
CAS:65277-42-1
Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
Formula:
C26H28Cl2N4O4
Purity:
99.61% - 99.62%
Color and Shape:
Crystals From 4-Methylpentanone Solid
Molecular weight:
531.43
Ref: TM-T0679
| 1g | 99.00 € | ||
| 5g | 343.00 € | ||
| 50mg | 44.00 € | ||
| 100mg | 55.00 € | ||
| 200mg | 67.00 € | ||
| 500mg | 83.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
K-Ras G12C-IN-4
CAS:2376328-55-9
K-Ras G12C-IN-4 is a potent co-valent Inhibitor of KRAS G12C..
Formula:
C31H33ClN4O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
561.07
Ref: TM-T11738
| 1mg | 72.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 543.00 € | ||
| 100mg | 797.00 € | ||
| 200mg | 1,072.00 € | ||
| 1mL*10mM (DMSO) | 196.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Sevelamer Carbonate
CAS:845273-93-0
Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.
Formula:
(C3H7N·C3H5ClO)x·xCH2O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
211.64
Ref: TM-T6666
| 25mg | 50.00 € | ||
| 100mg | 95.00 € | ||
| 200mg | 156.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
RMC-6236
CAS:2765081-21-6
RMC-6236 is a potent RAS(ON)MULTI inhibitor with broad-spectrum inhibitory activity against RAS-GTP.Cost-effective and quality-assured.
Formula:
C44H58N8O5S
Purity:
98.24% - 99.51%
Color and Shape:
Liquid
Molecular weight:
811.05
Ref: TM-T74698
| 1mg | 277.00 € | ||
| 5mg | 733.00 € | ||
| 10mg | 1,100.00 € | ||
| 25mg | 1,845.00 € | ||
| 50mg | 2,692.00 € | ||
| 100mg | 3,848.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized …
Formula:
C31H30F5N7O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
627.61
Ref: TM-T79166
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits …
Formula:
C51H65F4N9O9S2
Color and Shape:
Liquid
Molecular weight:
1088.24
Ref: TM-T200204
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
FAM49B (190-198) mouse
CAS:1588388-60-6
FAM49B (190-198) mouse represents a peptide fragment of the mitochondria-localized protein FAM49B, which is instrumental …
Formula:
C49H71N9O14S
Color and Shape:
Liquid
Molecular weight:
1042.2
Ref: TM-TP2834
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
ADT-007
CAS:1945941-09-2
ADT-007 is a pan-RAS inhibitor with potent anticancer activity.
Formula:
C26H24FNO5
Purity:
97.75%
Color and Shape:
Soild
Molecular weight:
449.47
Ref: TM-T85316
| 1mg | 49.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 129.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 366.00 € | ||
| 100mg | 624.00 € | ||
| 500mg | 2,359.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
MC 976
CAS:129831-99-8
MC 976 is a derivative of Vitamin D3.
Formula:
C27H42O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
414.63
Ref: TM-T16023
| 1mg | 1,039.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
(R)-BI-2852
CAS:2375482-49-6
(R)-5-hydroxy isoindolin-1-one is an RAS protein inhibitor with antiproliferative and antitumor properties.
Formula:
C31H28N6O2
Purity:
97.78%
Color and Shape:
Soild
Molecular weight:
516.59
Ref: TM-T72084
| 1mg | 138.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 399.00 € | ||
| 25mg | 646.00 € | ||
| 50mg | 898.00 € | ||
| 100mg | 1,198.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
GGTI298 Trifluoroacetate
CAS:1217457-86-7
GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and …
Formula:
C27H33N3O3S·C2HF3O2
Purity:
100% - 98.15%
Color and Shape:
Solid
Molecular weight:
593.66
Ref: TM-T6844
| 1mg | 87.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 239.00 € | ||
| 25mg | 463.00 € | ||
| 50mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 201.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
SOS1-IN-11
CAS:2654741-64-5
SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM).
Formula:
C22H24F3N5O
Purity:
98.79%
Color and Shape:
Solid
Molecular weight:
431.45
Ref: TM-T60029
| 1mg | 75.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 278.00 € | ||
| 25mg | 442.00 € | ||
| 50mg | 631.00 € | ||
| 100mg | 849.00 € | ||
| 1mL*10mM (DMSO) | 179.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
(E/Z)-ZINC09659342
CAS:591726-26-0
(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.
Formula:
C23H15F3N2O4
Purity:
95.83%
Color and Shape:
Liquid
Molecular weight:
440.37
Ref: TM-T9986
| 1mg | 64.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 214.00 € | ||
| 25mg | 365.00 € | ||
| 50mg | 516.00 € | ||
| 100mg | 694.00 € | ||
| 200mg | 906.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
CASIN
CAS:425399-05-9
CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
Formula:
C20H22N2O
Purity:
100% - 99.86%
Color and Shape:
Solid
Molecular weight:
306.4
Ref: TM-T3971
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 425.00 € | ||
| 500mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Arglabin
CAS:84692-91-1
Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, …
Formula:
C15H18O3
Purity:
99.62% - 99.62%
Color and Shape:
Solid
Molecular weight:
246.3
Ref: TM-TQ0165
| 1mg | 103.00 € | ||
| 5mg | 235.00 € | ||
| 10mg | 352.00 € | ||
| 25mg | 510.00 € | ||
| 50mg | 678.00 € | ||
| 100mg | 1,013.00 € | ||
| 1mL*10mM (DMSO) | 309.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
