Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Found 155 products of "Ras"
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MRTX-1257
CAS:<p>MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% target engagement.</p>Formula:C33H39N7O2Purity:97.3% - 99.07%Color and Shape:SolidMolecular weight:565.71HJC0197
CAS:<p>HJC0197 is a selective Epac antagonist; blocks cAMP-induced activation with IC50=5.9 μM for Epac2.</p>Formula:C19H21N3OSPurity:98.05%Color and Shape:SolidMolecular weight:339.45Ketoconazole
CAS:<p>Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.</p>Formula:C26H28Cl2N4O4Purity:99.53% - 99.62%Color and Shape:Crystals From 4-Methylpentanone SolidMolecular weight:531.43ARS-1630
CAS:<p>ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.</p>Formula:C21H17ClF2N4O2Purity:97.78%Color and Shape:SolidMolecular weight:430.84BI-3406
CAS:<p>BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.</p>Formula:C23H25F3N4O3Purity:99.2% - 99.66%Color and Shape:SolidMolecular weight:462.46RMC-6236
CAS:<p>RMC-6236 is a potent RAS(ON)MULTI inhibitor with broad-spectrum inhibitory activity against RAS-GTP.Cost-effective and quality-assured.</p>Formula:C44H58N8O5SPurity:98.24% - 99.92%Color and Shape:SolidMolecular weight:811.05K-Ras G12C-IN-4
CAS:<p>K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。</p>Formula:C31H33ClN4O4Purity:99.00%Color and Shape:SolidMolecular weight:561.07MBQ-167
CAS:<p>MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively).</p>Formula:C22H18N4Purity:98.07% - 99.52%Color and Shape:SolidMolecular weight:338.41KRAS inhibitor-38
CAS:<p>KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.</p>Formula:C53H68ClF2N9O8SColor and Shape:SolidMolecular weight:1064.68GGTI298 Trifluoroacetate
CAS:<p>GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.</p>Formula:C27H33N3O3S·C2HF3O2Purity:98.07% - >99.99%Color and Shape:SolidMolecular weight:593.66KRAS G12D inhibitor 20
<p>KRAS G12D inhibitor 20 (Compound 14) is a selective G12D KRAS inhibitor with antitumor activity.</p>Formula:C18H26N6OMolecular weight:342.21681Rapaprutug
CAS:<p>Rapaprutug is a monoclonal antibody that targets human KARS1 (lysyl-tRNA synthetase 1). It can block inflammation-related signaling pathways involving KARS1, thereby reducing the production and release of inflammatory factors. Rapaprutug shows potential for research into inflammatory diseases.</p>Color and Shape:LiquidG12 TFA
<p>G12 (Ras5-17) TFA is a wild-type Ras peptide comprising amino acids 5-17 (KLVVVGAGGVGKS). It serves as a control in studies involving mutant Ras peptides, such as V12.</p>Formula:C54H96F3N15O17Molecular weight:1283.70607pan-KRAS-IN-10
<p>Pan-KRAS-IN-10 (Compound 58) acts as an inhibitor of the human tumor mutant gene KRAS. It suppresses the proliferation of KRAS mutant cells, specifically AsPC-1 (G12D mutant) and SW480 (G12V mutant), with IC50 values of 0.7 and 0.24 nM, respectively.</p>Formula:C45H57N7O5SMolecular weight:807.41419KRpep-2d TFA
<p>KRpep-2d (TFA) is a potent inhibitor of K-Ras, effectively hindering the proliferation of K-Ras-driven cancer cells, thereby serving as a valuable asset for</p>Formula:C110H183F3N44O27S2Color and Shape:SolidMolecular weight:2675.03SOS1-IN-11
CAS:<p>SOS1-IN-11 is an effective inhibitor of SOS1 (IC50 = 30 nM).</p>Formula:C22H24F3N5OPurity:99.4%Color and Shape:SolidMolecular weight:431.45KRpep-2d
CAS:<p>KRpep-2d, a potent inhibitor of K-Ras, effectively suppresses the proliferation of cancer cells driven by K-Ras.</p>Formula:C109H183N43O25S2Color and Shape:SolidMolecular weight:2560.02Rac1 Inhibitor W56
CAS:<p>Peptide (45-60) blocks Rac1 binding with TrioN, GEF-H1, Tiam1 GEFs.</p>Formula:C74H117N19O23SPurity:98%Color and Shape:SolidMolecular weight:1671.93KRAS inhibitor-42
<p>KRAS inhibitor-42 (compound 8) is an effective USP7 inhibitor that exhibits high affinity for GDP-bound KRASG12D, with a Ki value of 2.7 μM.</p>Formula:C34H47ClN8O4S2Color and Shape:SolidMolecular weight:730.285026-Thio-GTP tetrasodium
<p>6-Thio-GTP (tetrasodium) is an inhibitor of Vav1-Rac. It can suppress TCR-induced T cell proliferation and CD28-mediated T cell survival. In a murine model of allogeneic heart transplantation, 6-Thio-GTP (tetrasodium) demonstrates immunosuppressive effects, which can prolong the survival time of heart transplants.</p>Formula:C10H12N5Na4O13P3SColor and Shape:SolidMolecular weight:626.89559SEPT9-IN-1
<p>SEPT9-IN-1 (compound 8b) is a SEPT9 inhibitor with an IC50 value of 94.83 μM. It exhibits cytotoxicity against human oral squamous carcinoma cells, with an IC50 of 21 µM.</p>Formula:C26H30ClN3O3Color and Shape:SolidMolecular weight:467.988(E/Z)-ZINC09659342
CAS:<p>(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.</p>Formula:C23H15F3N2O4Purity:>99.99%Color and Shape:SolidMolecular weight:440.37Ibetazol
<p>Ibetazol is an inhibitor of importin β1 (KPNB1), which functions by binding to Cys585 of importin β1, thus preventing importin β1-mediated nuclear import with an EC50 of 6.1 µM.</p>Formula:C13H11F3N2OSColor and Shape:SolidMolecular weight:300.3ADT-007
CAS:<p>ADT-007 is a pan-RAS inhibitor with potent anticancer activity.</p>Formula:C26H24FNO5Purity:97.75%Color and Shape:SoildMolecular weight:449.47MAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Color and Shape:Odour SolidMC 976
CAS:<p>MC 976 is a derivative of Vitamin D3.</p>Formula:C27H42O3Purity:98%Color and Shape:SolidMolecular weight:414.63KRAS G12C inhibitor 60
<p>KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized in the investigation of lung, colorectal, and</p>Formula:C31H30F5N7O2Purity:98%Color and Shape:SolidMolecular weight:627.61KS-58
CAS:<p>KS-58 is a derivative of KRpep-2d. It acts as an inhibitory peptide for K-Ras(G12D), selectively binding to K-Ras. KS-58 is capable of penetrating cells and interrupts the interaction between intracellular Ras and effector proteins. It inhibits the proliferation of tumor cells and exhibits antitumor activity.</p>Formula:C64H89FN12O14S2Color and Shape:SolidMolecular weight:1333.59Ras Inhibitory Peptide acetate
<p>Ras Inhibitory Peptide acetate, involved in cancer-related Ras signaling.</p>Formula:C55H95N19O13Purity:96.63%Color and Shape:SolidMolecular weight:1230.46KRAS inhibitor-33
<p>KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.</p>Formula:C33H39ClF2N6O3Color and Shape:SolidMolecular weight:641.15MRTF-A-IN-2
<p>MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.</p>Color and Shape:Odour SolidMRTF-A-IN-1
<p>MRTF-A-IN-1 (compound 14) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.</p>Formula:C22H21N3Color and Shape:SolidMolecular weight:327.42BI1701963
<p>BI1701963 is an orally effective inhibitor that targets the SOS1 and KRAS interaction, specifically inhibiting the activation of KRAS by blocking its GTP loading. This compound is utilized in cancer research to explore potential therapeutic effects against KRAS-driven malignancies.</p>Formula:C47H62N8O4SColor and Shape:SolidMolecular weight:835.11Pan-RAS-IN-7
CAS:<p>Pan-RAS-IN-7 (Compound D101) is a broad-spectrum RAS inhibitor used in the synthesis of antibody-drug conjugates (ADCs). It is also applicable in cancer research.</p>Formula:C59H76N8O8Color and Shape:SolidMolecular weight:1025.28KRASG12C IN-14
<p>KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.</p>Formula:C51H65F4N9O9S2Color and Shape:SolidMolecular weight:1088.24FAM49B (190-198) mouse
CAS:<p>FAM49B (190-198) mouse represents a peptide fragment of the mitochondria-localized protein FAM49B, which is instrumental in regulating mitochondrial fission, function, and integrity, in addition to influencing tumor progression. Beyond its role in mitochondrial dynamics, FAM49B serves as a negative regulator of T cell activation by inhibiting GTPase Rac activity and affecting cytoskeleton reorganization.</p>Formula:C49H71N9O14SColor and Shape:SolidMolecular weight:1042.2Sevelamer Carbonate
CAS:<p>Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.</p>Formula:(C3H7N·C3H5ClO)x·xCH2O3Purity:98%Color and Shape:SolidMolecular weight:211.64Y16
CAS:<p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>Formula:C24H20N2O3Purity:98.26% - 99.32%Color and Shape:SolidMolecular weight:384.43APS6-45
CAS:<p>APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.</p>Formula:C23H16F8N4O3Purity:99.39%Color and Shape:SolidMolecular weight:548.39CCG-100602
CAS:<p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>Formula:C21H17ClF6N2O2Purity:99.58%Color and Shape:SolidMolecular weight:478.82K-Ras(G12C) inhibitor 6
CAS:<p>Irreversible K-Ras(G12C) inhibitor 6 fully modifies the protein at 10 μM after 24h in vitro.</p>Formula:C17H22Cl2N2O3SPurity:89.07% - 97.09%Color and Shape:SolidMolecular weight:405.34Rhosin hydrochloride
CAS:<p>Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.</p>Formula:C20H20Cl2N6OPurity:97.33% - 98.92%Color and Shape:SolidMolecular weight:431.318CCG-203971
CAS:<p>CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.</p>Formula:C23H21ClN2O3Purity:98.82% - 99.50%Color and Shape:SolidMolecular weight:408.88ML141
CAS:<p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>Formula:C22H21N3O3SPurity:99.36% - 99.56%Color and Shape:SolidMolecular weight:407.49ARS-1620
CAS:<p>ARS-1620 is a covalent inhibitor of K-RASG12C.</p>Formula:C21H17ClF2N4O2Purity:98.86%Color and Shape:SolidMolecular weight:430.84Rasarfin
CAS:<p>Rasarfin inhibits Ras and ARF6.</p>Formula:C23H24ClN3O3Purity:97.98%Color and Shape:SolidMolecular weight:425.91Atranorin
CAS:<p>Atranorin has antinociceptive, anti-inflammatory, can be pro-oxidant or antioxidant, and protects cells from H(2)O(2)-induced oxidative stress.</p>Formula:C19H18O8Purity:98.76% - 99.57%Color and Shape:SolidMolecular weight:374.34CASIN
CAS:<p>CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).</p>Formula:C20H22N2OPurity:98.18% - >99.99%Color and Shape:SolidMolecular weight:306.4EHT 1864 2HCl
CAS:<p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>Formula:C25H29Cl2F3N2O4SPurity:98.39% - 99.42%Color and Shape:SolidMolecular weight:581.47Kobe0065
CAS:<p>Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.</p>Formula:C15H11ClF3N5O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:449.79FTI-277 hydrochloride
CAS:<p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>Formula:C22H30ClN3O3S2Purity:97.57% - 97.61%Color and Shape:SolidMolecular weight:484.07(S)-AMG-510
CAS:<p>(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and quality-assured.</p>Formula:C30H30F2N6O3Purity:99.05% - 99.76%Color and Shape:SolidMolecular weight:560.594K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formula:C15H17ClIN3O3Purity:97.16%Color and Shape:SolidMolecular weight:449.67ERK-IN-3
CAS:<p>ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.</p>Formula:C22H25ClFN7O2Purity:99.55% - 99.76%Color and Shape:SolidMolecular weight:473.93ASP2453
CAS:<p>ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.</p>Formula:C40H48F3N7O4Purity:99.71%Color and Shape:SolidMolecular weight:747.85CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Formula:C18H13ClF6N2O3Purity:99.80%Color and Shape:SolidMolecular weight:454.756H05 (TFA)
CAS:<p>6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.</p>Formula:C22H31ClF3N3O4S3Purity:98.83%Color and Shape:SolidMolecular weight:590.14SCH54292
CAS:<p>SCH-54292 is a GDP exchange inhibitor.</p>Formula:C24H28N2O9SPurity:95.65%Color and Shape:SolidMolecular weight:520.55ZT-12-037-01
CAS:<p>Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).</p>Formula:C21H31N5O2Purity:99.56%Color and Shape:SolidMolecular weight:385.5BAY-293
CAS:<p>BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).</p>Formula:C25H28N4O2SPurity:97.16%Color and Shape:SolidMolecular weight:448.58(Rac)-Antineoplaston A10
CAS:<p>Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.</p>Formula:C13H14N2O3Purity:98.41%Color and Shape:SolidMolecular weight:246.261A-116
CAS:<p>1A-116 is a specific Rac1 inhibitor.</p>Formula:C16H16F3N3Purity:99.71%Color and Shape:SolidMolecular weight:307.31K-Ras(G12C) inhibitor 9
CAS:<p>K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Formula:C16H21ClIN3O4SPurity:97.33% - 97.45%Color and Shape:SolidMolecular weight:513.78RBC8
CAS:<p>RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.</p>Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Adagrasib
CAS:<p>View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.</p>Formula:C32H35ClFN7O2Purity:99.10% - 99.9%Color and Shape:SolidMolecular weight:604.12MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Formula:C15H9NO3Purity:98.6%Color and Shape:SolidMolecular weight:251.24ML-097
CAS:<p>ML-097 (CID-2160985) is a pan activator of Ras-related GTPases</p>Formula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139ZCL278
CAS:<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>Formula:C21H19BrClN5O4S2Purity:96.29% - 99.72%Color and Shape:SolidMolecular weight:584.89EHop-016
CAS:<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Formula:C25H30N6OPurity:98.99% - >99.99%Color and Shape:SolidMolecular weight:430.551-(4-methansulfinylphenyl)ethanone
CAS:<p>The compound inhibits Ras function and therefore inhibits the abnormal growth of cells.</p>Formula:C9H10O2SPurity:99.48%Color and Shape:SolidMolecular weight:182.24ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Formula:C22H29ClN4O3Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:432.94Antineoplaston A10
CAS:<p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Phellodendrine chloride
CAS:<p>Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.</p>Formula:C20H24ClNO4Purity:98.85% - 99.05%Color and Shape:SolidMolecular weight:377.86NSC 23766 trihydrochloride
CAS:<p>NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs; no inhibitory for RhoA or Cdc42.</p>Formula:C24H35N7·3HClPurity:96.48% - 99.54%Color and Shape:SolidMolecular weight:530.96CID-1067700
CAS:<p>CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).</p>Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46CCG-222740
CAS:<p>CCG-222740 is an inhibitor of Rho/MRTF pathway</p>Formula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Salirasib
CAS:<p>Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.</p>Formula:C22H30O2SPurity:99.45%Color and Shape:SolidMolecular weight:358.54Kobe2602
CAS:<p>Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.</p>Formula:C14H9F4N5O4SPurity:98.36% - 99.39%Color and Shape:SolidMolecular weight:419.31Arglabin
CAS:<p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>Formula:C15H18O3Purity:98.97% - 99.62%Color and Shape:SolidMolecular weight:246.3BQU57
CAS:<p>BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.</p>Formula:C16H13F3N4OPurity:97.45% - 98.72%Color and Shape:SolidMolecular weight:334.3Sotorasib
CAS:<p>Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.</p>Formula:C30H30F2N6O3Purity:98% - 99.95%Color and Shape:SolidMolecular weight:560.594KRAS inhibitor-9
CAS:<p>KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.</p>Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81CID44216842
CAS:<p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>Formula:C22H20BrN3O3SPurity:99.66%Color and Shape:SolidMolecular weight:486.38Eicosapentaenoic Acid
CAS:<p>Eicosapentaenoic Acid is an ω-3 fatty acid and an inhibitor of fatty acid synthase (FASN). High-Quality, Low-Cost!</p>Formula:C20H30O2Purity:97.03% - 99.83%Color and Shape:LiquidMolecular weight:302.45K-Ras-IN-1
CAS:<p>K-Ras-IN-1 is a K-Ras inhibitor.</p>Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29MRTX1133
CAS:<p>View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.</p>Formula:C33H31F3N6O2Purity:97.39% - 99.6%Color and Shape:SolidMolecular weight:600.63ML-098
CAS:<p>ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).</p>Formula:C19H19NO3Purity:99.06% - 99.23%Color and Shape:SolidMolecular weight:309.36Lonafarnib
CAS:<p>Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).</p>Formula:C27H31Br2ClN4O2Purity:98% - 99.94%Color and Shape:SolidMolecular weight:638.82Oncrasin-1
CAS:<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Formula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73Z62954982
CAS:<p>Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteries</p>Formula:C20H21N3O5SPurity:98.28%Color and Shape:SolidMolecular weight:415.46AZD0022
CAS:<p>AZD0022 is a selective, reversible, and orally active KRAS G12D inhibitor, exhibits tumour marker inhibition in PDAC and NSCLC models.</p>Formula:C34H30F4N6OPurity:98.73%Color and Shape:SoildMolecular weight:614.64Deltarasin
CAS:<p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>Formula:C40H37N5OPurity:99.4%Color and Shape:SolidMolecular weight:603.756H05
CAS:<p>6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).</p>Formula:C20H30ClN3O2S3Purity:98%Color and Shape:SolidMolecular weight:476.12KRas G12C inhibitor 3
CAS:<p>KRas G12C inhibitor 3 is a compound that inhibits KRas G12C.</p>Formula:C32H36ClN7O2Purity:98%Color and Shape:SolidMolecular weight:586.13KRas G12C inhibitor 4
CAS:<p>KRas G12C inhibitor 4 is a compound that inhibits KRas G12C.</p>Formula:C33H38ClN7O2Purity:98%Color and Shape:SolidMolecular weight:600.15CCG-257081
CAS:<p>CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.</p>Formula:C24H19ClF3N3O2Purity:99.76% - 99.94%Color and Shape:SolidMolecular weight:473.87Digeranyl bisphosphonate
CAS:<p>Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl</p>Formula:C21H34Na4O6P2Purity:98.5%Color and Shape:SolidMolecular weight:536.4Nexinhib20
CAS:<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Formula:C15H16N4O3Purity:99.89%Color and Shape:SolidMolecular weight:300.31KRAS inhibitor-7
CAS:<p>KRAS inhibitor-7 is a potent KRAS G12C inhibitor.</p>Formula:C26H27ClF2N6O2Purity:98%Color and Shape:SolidMolecular weight:528.98
