Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
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Kobe0065
CAS:436133-68-5
Kobe0065: novel small-molecule, inhibits Ras-Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.
Formula:
C15H11ClF3N5O4S
Purity:
100% - 99.58%
Color and Shape:
Solid
Molecular weight:
449.79
Ref: TM-T1876
| 5mg | 46.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 139.00 € | ||
| 100mg | 217.00 € | ||
| 200mg | 361.00 € | ||
| 500mg | 600.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KRAS inhibitor-9
CAS:300809-71-6
KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, …
Formula:
C13H9ClN2S2
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
292.81
Ref: TM-T8756
| 1mg | 60.00 € | ||
| 2mg | 84.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 648.00 € | ||
| 1mL*10mM (DMSO) | 142.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Phellodendrine chloride
CAS:104112-82-5
Phellodendrine chloride combats kidney inflammation by blocking macrophage and T cell activity in glomeruli.
Formula:
C20H24ClNO4
Purity:
98.85% - 99.05%
Color and Shape:
Solid
Molecular weight:
377.86
Ref: TM-T5S0777
| 2mg | 39.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 77.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 226.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CID44216842
CAS:1222513-26-9
CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; …
Formula:
C22H20BrN3O3S
Purity:
99.66%
Color and Shape:
Solid
Molecular weight:
486.38
Ref: TM-T8930
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 249.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 521.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Oncrasin-1
CAS:75629-57-1
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells …
Formula:
C16H12ClNO
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
269.73
Ref: TM-T8006
| 5mg | 35.00 € | ||
| 10mg | 47.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 314.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Lonafarnib
CAS:193275-84-2
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 …
Formula:
C27H31Br2ClN4O2
Purity:
98% - 99.04%
Color and Shape:
Solid
Molecular weight:
638.82
Ref: TM-T6302
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 292.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 646.00 € | ||
| 1mL*5mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Y16
CAS:429653-73-6
Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG …
Formula:
C24H20N2O3
Purity:
98.26% - 99.32%
Color and Shape:
Solid
Molecular weight:
384.43
Ref: TM-T3553
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 407.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
FTI-277 hydrochloride
CAS:180977-34-8
FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.
Formula:
C22H30ClN3O3S2
Purity:
97.57% - 98.19%
Color and Shape:
Solid
Molecular weight:
484.07
Ref: TM-T2700
| 1mg | 52.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 318.00 € | ||
| 50mg | 530.00 € | ||
| 100mg | 742.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML-098
CAS:878978-76-8
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).
Formula:
C19H19NO3
Purity:
99.06% - 99.52%
Color and Shape:
Solid
Molecular weight:
309.36
Ref: TM-T4619
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 196.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 386.00 € | ||
| 500mg | 913.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
(S)-AMG-510
CAS:2252403-56-6
(S)-AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C.Cost-effective and …
Formula:
C30H30F2N6O3
Purity:
98.01% - 98.57%
Color and Shape:
Solid
Molecular weight:
560.59
Ref: TM-T22258
| 2mg | 36.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 268.00 € | ||
| 100mg | 420.00 € | ||
| 500mg | 917.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
K-Ras(G12C) inhibitor 12
CAS:1469337-95-8
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).
Formula:
C15H17ClIN3O3
Purity:
97.16%
Color and Shape:
Solid
Molecular weight:
449.67
Ref: TM-T6555
| 1mg | 48.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 140.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 101.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
NSC 23766 trihydrochloride
CAS:1177865-17-6
NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by …
Formula:
C24H35N7·3HCl
Purity:
96.48% - 99.54%
Color and Shape:
Solid
Molecular weight:
530.96
Ref: TM-T6342
| 5mg | 56.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 398.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CID-1067700
CAS:314042-01-8
CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 …
Formula:
C18H18N2O4S2
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
390.48
Ref: TM-T7558
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 241.00 € | ||
| 100mg | 312.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ERK-IN-3
CAS:2055597-12-9
ERK-IN-3 (ASN007 free base) is a potent and orally active inhibitor of ERK.
Formula:
C22H25ClFN7O2
Purity:
99.55% - 99.76%
Color and Shape:
Solid
Molecular weight:
473.93
Ref: TM-T9141
| 1mg | 60.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 280.00 € | ||
| 50mg | 457.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ASP2453
CAS:2241719-73-1
ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.
Formula:
C40H48F3N7O4
Purity:
96.57%
Color and Shape:
Liquid
Molecular weight:
747.85
Ref: TM-T39738
| 1mg | 114.00 € | ||
| 5mg | 277.00 € | ||
| 10mg | 418.00 € | ||
| 25mg | 649.00 € | ||
| 50mg | 872.00 € | ||
| 1mL*10mM (DMSO) | 432.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CCG-1423
CAS:285986-88-1
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.
Formula:
C18H13ClF6N2O3
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
454.75
Ref: TM-T2014
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 159.00 € | ||
| 100mg | 256.00 € | ||
| 200mg | 399.00 € | ||
| 500mg | 646.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
6H05 (TFA)
CAS:2061344-88-3
6H05 TFA (6H05 trifluoroacetate) is a selective, and allosteric oncogenic mutant K-Ras(G12C) inhibitor.
Formula:
C22H31ClF3N3O4S3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
590.14
Ref: TM-T7326
| 1mg | 68.00 € | ||
| 2mg | 94.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 369.00 € | ||
| 50mg | 559.00 € | ||
| 100mg | 789.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SCH54292
CAS:188480-51-5
SCH-54292 is a GDP exchange inhibitor.
Formula:
C24H28N2O9S
Purity:
95.65%
Color and Shape:
Solid
Molecular weight:
520.55
Ref: TM-T9198
| 1mg | 129.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 420.00 € | ||
| 25mg | 692.00 € | ||
| 50mg | 975.00 € | ||
| 1mL*10mM (DMSO) | 362.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ZT-12-037-01
CAS:2328073-61-4
Zt-12-037-01 is a ATP competitive STK19 inhibitor(IC50 values of 23.96 nM and 27.94 nM for …
Formula:
C21H31N5O2
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
385.5
Ref: TM-T5597
| 1mg | 35.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 362.00 € | ||
| 100mg | 566.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
MRTX1133
CAS:2621928-55-8
View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS …
Formula:
C33H31F3N6O2
Purity:
97.39% - 99.10%
Color and Shape:
Solid
Molecular weight:
600.63
Ref: TM-T9303
| 1mg | 185.00 € | ||
| 5mg | 397.00 € | ||
| 10mg | 607.00 € | ||
| 25mg | 932.00 € | ||
| 50mg | 1,318.00 € | ||
| 100mg | 1,794.00 € | ||
| 1mL*10mM (DMSO) | 523.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
