ERK
ERK is a key protein in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway, which is involved in transmitting signals from cell surface receptors to the DNA in the cell nucleus. ERK plays a crucial role in the regulation of various cellular processes, including proliferation, differentiation, and survival. Dysregulation of ERK signaling is associated with the development of cancer and other diseases, making it an important target for therapeutic intervention. At CymitQuimica, we offer a selection of high-quality ERK inhibitors and modulators to support your research in cell signaling, oncology, and therapeutic development.
Found 193 products of "ERK"
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TAT-DEF-Elk-1
CAS:<p>TAT-DEF-Elk-1 is a cell-penetrating peptide Elk-1 inhibitor.</p>Formula:C155H259N57O40Purity:98%Color and Shape:SolidMolecular weight:3561.1364-P-PDOT
CAS:<p>4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.</p>Formula:C19H21NOPurity:99.91%Color and Shape:SolidMolecular weight:279.38ROCK-IN-5
CAS:<p>ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.</p>Formula:C16H11ClFN3OSPurity:99.72% - 99.83%Color and Shape:SolidMolecular weight:347.79PROTAC MEK1 Degrader-1
CAS:<p>PROTAC MEK1 Degrader-1, a targeted protein degradation agent, combines a MEK1 inhibitor with a von Hippel-Lindau ligand to effectively inhibit ERK1/2</p>Formula:C53H66FIN8O11S2Purity:98%Color and Shape:SolidMolecular weight:1201.17Emodic acid
CAS:<p>Emodic acid is a useful organic compound for research related to life sciences. The catalog number is T124807 and the CAS number is 478-45-5.</p>Formula:C15H8O7Color and Shape:SolidMolecular weight:300.222ERK1/2 inhibitor 3
CAS:<p>ERK1/2 inhibitor 3, a strong ERK1/2 blocker, may aid in cancer and inflammation research.</p>Formula:C28H31ClFN5O6SColor and Shape:SolidMolecular weight:620.09Anti-inflammatory agent 31
<p>Andrographolide derivative 31 is an anti-inflammatory that blocks NF-κB, PI3K/Akt, and ERK1/2 MAPK, and restores GSH levels to protect the liver.</p>Formula:C19H30O3Color and Shape:SolidMolecular weight:306.44Olomoucine
CAS:<p>Olomoucine hinders Cdk2, Cdc2, CDK5, ERK1, regulates the cell cycle, and fights melanoma; IC50s: 3-25 µM.</p>Formula:C15H18N6OPurity:99.77%Color and Shape:White Crystalline PowderMolecular weight:298.344′-Demethylnobiletin
CAS:<p>4′-Demethylnobiletin, a bioactive metabolite, activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and</p>Formula:C20H20O8Color and Shape:SolidMolecular weight:388.37Edaxeterkib
CAS:<p>Edaxeterkib is a potent extracellular signal- regulated kinase (ERK) inhibitor for the research of cancer.</p>Formula:C26H27N7O2Color and Shape:SolidMolecular weight:469.549PD 198306
CAS:<p>PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.</p>Formula:C18H16F3IN2O2Purity:99.66%Color and Shape:SolidMolecular weight:476.23Anti-inflammatory agent 35
CAS:<p>Anti-inflammatory agent 35 is a potent anti-inflammatory agent.</p>Formula:C27H29NO8Purity:99.98%Color and Shape:SoildMolecular weight:495.52SOS1-IN-18
<p>SOS1-IN-18 (Compound 8) is an inhibitor of the Son of Sevenless 1 protein (SOS1) with a dissociation constant (KD) of 2.6 nM. It disrupts the SOS1-KRAS G12C interaction with an IC50 of 3.4 nM, inhibits ERK phosphorylation in H358 cells with an IC50 of 31 nM, and curtails the proliferation of H358 cells with an IC50 of 5 nM.</p>Formula:C26H29F3N4O2Color and Shape:SolidMolecular weight:486.53MAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Color and Shape:Odour SolidRineterkib hydrochloride
CAS:<p>Rineterkib hydrochloride (B) is an oral RAF/ERK1/2 inhibitor for MAPK-driven cancers, including KRAS/BRAF-mutant NSCLC and CRC.</p>Formula:C26H28BrClF3N5O2Color and Shape:SolidMolecular weight:614.89VSLRGDTRG
CAS:<p>VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.</p>Formula:C38H69N15O14Color and Shape:SolidMolecular weight:960.047LC-SF-14
<p>LC-SF-14 is a selective dual inhibitor of SHP2 and FGFR, with IC50 values of 71.6 nM and 8.9 nM, respectively. It blocks FGFR2-FRS2α-SHP2-MAPK signaling and ERK phosphorylation, and also inhibits the proliferation of KATOIII cancer cells (IC50: 9.2 nM). Furthermore, LC-SF-14 exhibits antitumor activity in SNU-16 xenograft mouse models, making it suitable for research on FGFR2-driven gastric cancer.</p>Formula:C44H50Cl3N13O5SColor and Shape:SolidMolecular weight:977.28442GSK143
CAS:<p>GSK143: Oral SYK inhibitor, pIC50=7.5, curbs pErk, anti-inflammatory, hinders immune cells in mice.</p>Formula:C17H22N6O2Color and Shape:SolidMolecular weight:342.403Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Color and Shape:Odour SolidFulipiftide
CAS:<p>Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF). It stimulates the amplification of nuclear stem cell factor+TSPC by activating the ERK2 and STAT3 signaling pathways. Fulipiftide also exhibits anti-inflammatory properties and is applicable in research on acute tendon injuries.</p>Formula:C144H227N41O47Color and Shape:SolidMolecular weight:3284.59
