TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
Read more
TRPC6-PAM-C20
CAS:667427-75-0
TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, …
Formula:
C22H21NO4
Purity:
98.16%
Color and Shape:
Liquid
Molecular weight:
363.41
Ref: TM-T37428
| 1mg | 170.00 € | ||
| 5mg | 432.00 € | ||
| 10mg | 638.00 € | ||
| 25mg | 1,008.00 € | ||
| 50mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 465.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
ABT-239
CAS:460746-46-7
ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 …
Formula:
C22H22N2O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
330.42
Ref: TM-T14087
| 1mg | 48.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 354.00 € | ||
| 50mg | 528.00 € | ||
| 100mg | 743.00 € | ||
| 500mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
D-3263 hydrochloride
CAS:1008763-54-9
D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 …
Formula:
C21H32ClN3O3
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
409.95
Ref: TM-T10929L
| 1mg | 50.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
AM12
CAS:2387510-84-9
AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).
Formula:
C15H9BrO5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
349.13
Ref: TM-T13546
| 10mg | 3,133.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Elismetrep
CAS:1400699-64-0
Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study …
Formula:
C27H21F3N2O5S
Purity:
99.57% - 99.86%
Color and Shape:
Solid
Molecular weight:
542.53
Ref: TM-T27253
| 1mg | 124.00 € | ||
| 5mg | 298.00 € | ||
| 10mg | 465.00 € | ||
| 25mg | 929.00 € | ||
| 50mg | 1,388.00 € | ||
| 100mg | 1,872.00 € | ||
| 200mg | 2,527.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Mavatrep
CAS:956274-94-5
Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can …
Formula:
C25H21F3N2O
Purity:
98.01% - 98.38%
Color and Shape:
Solid
Molecular weight:
422.44
Ref: TM-T16014
| 1mg | 66.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 227.00 € | ||
| 25mg | 454.00 € | ||
| 50mg | 733.00 € | ||
| 100mg | 1,169.00 € | ||
| 500mg | 2,365.00 € | ||
| 1mL*10mM (DMSO) | 159.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Olvanil
CAS:58493-49-5
Olvanil (N-Vannilyloleoylamide) is a vanilloid receptor agonist with EC50 of 0.7nM.
Formula:
C26H43NO3
Purity:
95.06%
Color and Shape:
Solid
Molecular weight:
417.62
Ref: TM-T23106
| 1mg | 50.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 164.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 378.00 € | ||
| 100mg | 540.00 € | ||
| 200mg | 730.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
GSK1702934A
CAS:924377-85-5
GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in …
Formula:
C22H25N3O2S
Purity:
98.15%
Color and Shape:
Solid
Molecular weight:
395.52
Ref: TM-T15425
| 1mg | 75.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
TRPV4 agonist-1
CAS:2314467-60-0
TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).
Formula:
C25H23ClF2N4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
484.93
Ref: TM-T13214
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
TRPM4-IN-2
CAS:667411-04-3
NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in …
Formula:
C19H14ClNO4
Purity:
99.21%
Color and Shape:
Liquid
Molecular weight:
355.77
Ref: TM-T61275
| 2mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Jun 2025
HC-070
CAS:1628291-95-1
HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).
Formula:
C22H20Cl2N4O4
Purity:
97.06%
Color and Shape:
Solid
Molecular weight:
475.32
Ref: TM-T15465
| 1mg | 88.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 429.00 € | ||
| 50mg | 605.00 € | ||
| 100mg | 815.00 € | ||
| 200mg | 1,093.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
EIPA hydrochloride
CAS:1345839-28-2
EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel …
Formula:
C11H19Cl2N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
336.22
Ref: TM-T11172
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Jun 2025
RN9893
CAS:1803003-68-0
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 …
Formula:
C21H23F3N4O5S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
500.49
Ref: TM-T28548
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 274.00 € | ||
| 50mg | 406.00 € | ||
| 100mg | 592.00 € | ||
| 500mg | 1,216.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
TRPV3 antagonist 74a
CAS:1432051-63-2
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological …
Formula:
C17H17F3N2O2
Purity:
≥98.0%
Color and Shape:
Liquid
Molecular weight:
338.32
Ref: TM-T37429
| 1mg | 475.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
AMG-0347
CAS:946615-43-6
AMG-0347 inhibits TRPA1 ion channels in sensory neurons, blocking pain perception.
Formula:
C24H26F3N3O2
Purity:
99.7%
Color and Shape:
Solid
Molecular weight:
445.48
Ref: TM-T29968
| 1mg | 226.00 € | ||
| 5mg | 552.00 € | ||
| 10mg | 735.00 € | ||
| 25mg | 1,111.00 € | ||
| 50mg | 1,491.00 € | ||
| 100mg | 2,005.00 € | ||
| 200mg | 2,707.00 € | ||
| 1mL*10mM (DMSO) | 567.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
PF-05105679
CAS:1398583-31-7
PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in …
Formula:
C26H21FN2O3
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
428.45
Ref: TM-T16483
| 1mg | 48.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 160.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 710.00 € | ||
| 200mg | 938.00 € | ||
| 500mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
Mesendogen
CAS:864716-85-8
Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) …
Formula:
C18H16ClF3N2OS
Purity:
98.90%
Color and Shape:
Solid
Molecular weight:
400.85
Ref: TM-T28020
| 1mg | 43.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 535.00 € | ||
| 100mg | 753.00 € | ||
| 1mL*10mM (DMSO) | 103.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
JT010
CAS:917562-33-5
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
Formula:
C16H19ClN2O3S
Purity:
98.5%
Color and Shape:
Solid
Molecular weight:
354.85
Ref: TM-T15628
| 2mg | 34.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
A 425619
CAS:581809-67-8
A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist
Formula:
C18H14F3N3O
Purity:
99.35%
Color and Shape:
Solid
Molecular weight:
345.32
Ref: TM-T8562
| 1mg | 88.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 425.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 810.00 € | ||
| 200mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 177.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
MK-2295
CAS:878811-00-8
MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment …
Formula:
C27H31FN6O2
Purity:
98.1% - 98.83%
Color and Shape:
Solid
Molecular weight:
490.57
Ref: TM-T33429
| 1mg | 77.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 338.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 632.00 € | ||
| 200mg | 853.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
