TRP/TRPV Channel

TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.

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Product data	Purity	Price range	Estimated delivery
M8-B Hydrochloride REF: TM-T8442CAS: 883976-12-3	99.33%	35.00 €~452.00 €	Fri 13 Dec 24
RQ-00203078 REF: TM-T2007CAS: 1254205-52-1	98% - 99.17%	50.00 €~345.00 €	Fri 13 Dec 24
A-967079 REF: TM-T7205CAS: 1170613-55-4	98.34% - 99.75%	54.00 €~419.00 €	Fri 13 Dec 24
SB-366791 REF: TM-T6977CAS: 472981-92-3	99.12%	35.00 €~291.00 €	Fri 13 Dec 24
ICILIN REF: TM-T1814CAS: 36945-98-9	97.61% - ≥95%	36.00 €~292.00 €	Fri 13 Dec 24
BCTC REF: TM-T7102CAS: 393514-24-4	≥95%	36.00 €~318.00 €	Fri 13 Dec 24
HC-067047 REF: TM-T4680CAS: 883031-03-6	99.45% - 99.79%	35.00 €~491.00 €	Fri 13 Dec 24
AM-0902 REF: TM-T7430CAS: 1883711-97-4	100%	35.00 €~500.00 €	Fri 13 Dec 24
Pyr6 REF: TM-T16688CAS: 245747-08-4	99.18%	36.00 €~296.00 €	Fri 13 Dec 24
SB 452533 REF: TM-T23322CAS: 459429-39-1	98.52%	41.00 €~1,425.00 €	Fri 13 Dec 24
ASP7663 REF: TM-T8410CAS: 1190217-35-6	98.11%	39.00 €~486.00 €	Fri 13 Dec 24
Pico145 REF: TM-T16532CAS: 1628287-16-0	99.06%	114.00 €~1,328.00 €	Fri 13 Dec 24
TRPM4-IN-1 REF: TM-T9245CAS: 351424-20-9	97.22%	45.00 €~491.00 €	Fri 13 Dec 24
AC1903 REF: TM-T8528CAS: 831234-13-0	98.45%	To inquire	Fri 13 Dec 24
MK6-83 REF: TM-T24477CAS: 1062271-24-2	99.71%	48.00 €~553.00 €	Fri 13 Dec 24
9-Phenanthrol REF: TM-T22537CAS: 484-17-3	98.72%	48.00 €~107.00 €	Fri 13 Dec 24
TC-I2000 REF: TM-T8449CAS: 1159996-20-9	98.87%	35.00 €~249.00 €	Fri 13 Dec 24
AMG 517 REF: TM-T6379CAS: 659730-32-2	99.66% - 99.85%	51.00 €~517.00 €	Fri 13 Dec 24
WS-12 REF: TM-T7416CAS: 68489-09-8	99.99%	35.00 €~663.00 €	Fri 13 Dec 24
Ononetin REF: TM-T23107CAS: 487-49-0	98.15%	51.00 €~686.00 €	Fri 13 Dec 24

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M8-B Hydrochloride

CAS:883976-12-3

M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.

Formula:

C₂₂H₂₅ClN₂O₃S

Purity:

99.33%

Color and Shape:

Solid

Molecular weight:

432.96

Ref: TM-T8442

2mg		35.00 €
5mg		51.00 €
10mg		72.00 €
25mg		141.00 €
50mg		218.00 €
100mg		324.00 €
200mg		452.00 €
1mL*10mM (DMSO)		62.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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RQ-00203078

CAS:1254205-52-1

RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.

Formula:

C₂₁H₁₃ClF₆N₂O₅S

Purity:

98% - 99.17%

Color and Shape:

Solid

Molecular weight:

554.85

Ref: TM-T2007

5mg		50.00 €
10mg		78.00 €
25mg		121.00 €
50mg		183.00 €
100mg		345.00 €
1mL*10mM (DMSO)		58.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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A-967079

CAS:1170613-55-4

A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 …

Formula:

C₁₂H₁₄FNO

Purity:

98.34% - 99.75%

Color and Shape:

Solid

Molecular weight:

207.24

Ref: TM-T7205

5mg		54.00 €
10mg		73.00 €
25mg		145.00 €
50mg		245.00 €
100mg		419.00 €
1mL*10mM (DMSO)		65.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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SB-366791

CAS:472981-92-3

SB-366791 is a new and selective cinnamide TRPV1 antagonist.

Formula:

C₁₆H₁₄ClNO₂

Purity:

99.12%

Color and Shape:

Solid

Molecular weight:

287.74

Ref: TM-T6977

5mg		35.00 €
10mg		44.00 €
25mg		87.00 €
50mg		123.00 €
100mg		196.00 €
200mg		291.00 €
1mL*10mM (DMSO)		35.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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ICILIN

CAS:36945-98-9

ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.

Formula:

C₁₆H₁₃N₃O₄

Purity:

97.61% - ≥95%

Color and Shape:

Light Yellow Solid

Molecular weight:

311.29

Ref: TM-T1814

5mg		36.00 €
10mg		57.00 €
25mg		95.00 €
50mg		169.00 €
100mg		292.00 €
1mL*10mM (DMSO)		41.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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BCTC

CAS:393514-24-4

BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 …

Formula:

C₂₀H₂₅ClN₄O

Purity:

≥95%

Color and Shape:

Solid

Molecular weight:

372.89

Ref: TM-T7102

5mg		36.00 €
10mg		47.00 €
25mg		87.00 €
50mg		147.00 €
100mg		214.00 €
200mg		318.00 €
1mL*10mM (DMSO)		41.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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HC-067047

CAS:883031-03-6

HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH …

Formula:

C₂₆H₂₈F₃N₃O₂

Purity:

99.45% - 99.79%

Color and Shape:

Solid

Molecular weight:

471.51

Ref: TM-T4680

1mg		35.00 €
5mg		67.00 €
10mg		95.00 €
25mg		185.00 €
50mg		306.00 €
100mg		491.00 €
1mL*10mM (DMSO)		68.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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AM-0902

CAS:1883711-97-4

AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).

Formula:

C₁₇H₁₅ClN₆O₂

Purity:

100%

Color and Shape:

Solid

Molecular weight:

370.79

Ref: TM-T7430

2mg		35.00 €
5mg		49.00 €
10mg		68.00 €
25mg		127.00 €
50mg		238.00 €
100mg		352.00 €
200mg		500.00 €
1mL*10mM (DMSO)		54.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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Pyr6

CAS:245747-08-4

Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx

Formula:

C₁₇H₉F₇N₄O

Purity:

99.18%

Color and Shape:

Solid

Molecular weight:

418.27

Ref: TM-T16688

5mg		36.00 €
10mg		56.00 €
25mg		92.00 €
50mg		123.00 €
1mL*10mM (DMSO)		41.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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SB 452533

CAS:459429-39-1

SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).

Formula:

C₁₈H₂₂BrN₃O

Purity:

98.52%

Color and Shape:

Solid

Molecular weight:

376.29

Ref: TM-T23322

2mg		41.00 €
5mg		62.00 €
10mg		93.00 €
25mg		177.00 €
50mg		274.00 €
100mg		398.00 €
200mg		565.00 €
1mL*10mM (DMSO)		82.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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ASP7663

CAS:1190217-35-6

ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.

Formula:

C₁₄H₁₄FNO₃

Purity:

98.11%

Color and Shape:

Solid

Molecular weight:

263.26

Ref: TM-T8410

1mg		39.00 €
5mg		81.00 €
10mg		109.00 €
25mg		213.00 €
50mg		323.00 €
100mg		486.00 €
1mL*10mM (DMSO)		89.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

+ info

Pico145

CAS:1628287-16-0

Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.

Formula:

C₂₃H₂₀ClF₃N₄O₅

Purity:

99.06%

Color and Shape:

Solid

Molecular weight:

524.88

Ref: TM-T16532

1mg		114.00 €
5mg		271.00 €
10mg		427.00 €
25mg		699.00 €
50mg		984.00 €
100mg		1,328.00 €
1mL*10mM (DMSO)		314.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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TRPM4-IN-1

CAS:351424-20-9

TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of …

Formula:

C₁₅H₁₁Cl₂NO₄

Purity:

97.22%

Color and Shape:

Solid

Molecular weight:

340.16

Ref: TM-T9245

5mg		45.00 €
10mg		66.00 €
25mg		129.00 €
50mg		210.00 €
100mg		340.00 €
200mg		491.00 €
1mL*10mM (DMSO)		73.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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AC1903

CAS:831234-13-0

AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe …

Formula:

C₁₉H₁₇N₃O

Purity:

98.45%

Color and Shape:

Solid

Molecular weight:

303.36

Ref: TM-T8528

5mg		48.00 €
10mg		70.00 €
25mg		126.00 €
50mg		201.00 €
100mg		300.00 €
1mL*10mM (DMSO)		52.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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MK6-83

CAS:1062271-24-2

MK6-83 is the transient receptor potential channel ML3 agonist.

Formula:

C₁₆H₂₀N₂O₂S₂

Purity:

99.71%

Color and Shape:

Solid

Molecular weight:

336.47

Ref: TM-T24477

2mg		48.00 €
5mg		72.00 €
10mg		95.00 €
25mg		185.00 €
50mg		324.00 €
100mg		553.00 €
1mL*10mM (DMSO)		79.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

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9-Phenanthrol

CAS:484-17-3

9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated …

Formula:

C₁₄H₁₀O

Purity:

98.72%

Color and Shape:

Solid

Molecular weight:

194.23

Ref: TM-T22537

25mg		48.00 €
50mg		57.00 €
100mg		82.00 €
200mg		107.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

+ info

TC-I2000

CAS:1159996-20-9

TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells …

Formula:

C₂₃H₁₈F₄N₂O

Purity:

98.87%

Color and Shape:

Liquid

Molecular weight:

414.4

Ref: TM-T8449

5mg		35.00 €
10mg		49.00 €
25mg		86.00 €
50mg		116.00 €
100mg		168.00 €
200mg		249.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

+ info

AMG 517

CAS:659730-32-2

AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin …

Formula:

C₂₀H₁₃F₃N₄O₂S

Purity:

99.66% - 99.85%

Color and Shape:

Solid

Molecular weight:

430.4

Ref: TM-T6379

5mg		51.00 €
10mg		96.00 €
25mg		183.00 €
50mg		346.00 €
100mg		517.00 €
1mL*10mM (DMSO)		57.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

+ info

WS-12

CAS:68489-09-8

WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 …

Formula:

C₁₈H₂₇NO₂

Purity:

99.99%

Color and Shape:

Whitish To White Solid Crystalline

Molecular weight:

289.41

Ref: TM-T7416

1mg		35.00 €
5mg		75.00 €
10mg		100.00 €
25mg		169.00 €
50mg		212.00 €
100mg		276.00 €
500mg		663.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

+ info

Ononetin

CAS:487-49-0

Ononetin (2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone) is a TRPM3 channel blocker(IC50: 0.3 μM).

Formula:

C₁₅H₁₄O₄

Purity:

98.15%

Color and Shape:

Solid

Molecular weight:

258.27

Ref: TM-T23107

5mg		51.00 €
10mg		78.00 €
25mg		135.00 €
50mg		186.00 €
100mg		279.00 €
200mg		427.00 €
500mg		686.00 €

Estimated delivery in United States, on Friday 13 Dec 2024

+ info