TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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RQ-00203078
CAS:1254205-52-1
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
Formula:
C21H13ClF6N2O5S
Purity:
98% - 99.17%
Color and Shape:
Solid
Molecular weight:
554.85
Ref: TM-T2007
| 5mg | 50.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
A-967079
CAS:1170613-55-4
A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 …
Formula:
C12H14FNO
Purity:
98.34% - 99.75%
Color and Shape:
Solid
Molecular weight:
207.24
Ref: TM-T7205
| 5mg | 55.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 427.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AMG 517
CAS:659730-32-2
AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin …
Formula:
C20H13F3N4O2S
Purity:
99.77% - 99.85%
Color and Shape:
Solid
Molecular weight:
430.4
Ref: TM-T6379
| 5mg | 51.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 354.00 € | ||
| 100mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
ICILIN
CAS:36945-98-9
ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.
Formula:
C16H13N3O4
Purity:
97.61% - ≥95%
Color and Shape:
Light Yellow Solid
Molecular weight:
311.29
Ref: TM-T1814
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 296.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
BCTC
CAS:393514-24-4
BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 …
Formula:
C20H25ClN4O
Purity:
99.21%
Color and Shape:
Solid
Molecular weight:
372.89
Ref: TM-T7102
| 5mg | 37.00 € | ||
| 10mg | 48.00 € | ||
| 25mg | 89.00 € | ||
| 50mg | 153.00 € | ||
| 100mg | 221.00 € | ||
| 200mg | 329.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
HC-067047
CAS:883031-03-6
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH …
Formula:
C26H28F3N3O2
Purity:
99.45% - 99.79%
Color and Shape:
Solid
Molecular weight:
471.51
Ref: TM-T4680
| 1mg | 35.00 € | ||
| 5mg | 67.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 502.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
AM-0902
CAS:1883711-97-4
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
Formula:
C17H15ClN6O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
370.79
Ref: TM-T7430
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 131.00 € | ||
| 50mg | 246.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
JNJ-17203212
CAS:821768-06-3
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 …
Formula:
C17H15F6N5O
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
419.32
Ref: TM-T7526
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 187.00 € | ||
| 100mg | 281.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Pyr6
CAS:245747-08-4
Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx
Formula:
C17H9F7N4O
Purity:
98.89%
Color and Shape:
Solid
Molecular weight:
418.27
Ref: TM-T16688
| 5mg | 37.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 126.00 € | ||
| 1mL*10mM (DMSO) | 42.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SB 452533
CAS:459429-39-1
SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).
Formula:
C18H22BrN3O
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
376.29
Ref: TM-T23322
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 183.00 € | ||
| 50mg | 284.00 € | ||
| 100mg | 411.00 € | ||
| 200mg | 585.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Pico145
CAS:1628287-16-0
Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.
Formula:
C23H20ClF3N4O5
Purity:
99.06%
Color and Shape:
Solid
Molecular weight:
524.88
Ref: TM-T16532
| 1mg | 116.00 € | ||
| 5mg | 276.00 € | ||
| 10mg | 434.00 € | ||
| 25mg | 715.00 € | ||
| 50mg | 1,008.00 € | ||
| 100mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 315.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
SAR7334
CAS:1333210-07-3
SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
Formula:
C21H22ClN3O
Purity:
99.62% - 99.71%
Color and Shape:
Solid
Molecular weight:
367.87
Ref: TM-T12849
| 1mg | 71.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 401.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 707.00 € | ||
| 200mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 29 Apr 2025
Asivatrep
CAS:1005168-10-4
Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 …
Formula:
C21H22F5N3O3S
Purity:
95.13%
Color and Shape:
Solid
Molecular weight:
491.48
Ref: TM-T16426
| 5mg | 357.00 € | ||
| 25mg | 1,155.00 € | ||
| 50mg | 1,508.00 € | ||
| 100mg | 1,950.00 € | ||
| 1mL*10mM (DMSO) | 386.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Pyr3
CAS:1160514-60-2
Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.
Formula:
C16H11Cl3F3N3O3
Purity:
99.47%
Color and Shape:
Solid
Molecular weight:
456.63
Ref: TM-T16687
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 77.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 512.00 € | ||
| 200mg | 738.00 € | ||
| 500mg | 1,121.00 € | ||
| 1mL*10mM (DMSO) | 86.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
SET 2
CAS:2313525-20-9
SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 …
Formula:
C17H21F3N4O2S
Purity:
98.43%
Color and Shape:
Liquid
Molecular weight:
402.43
Ref: TM-T37097
| 5mg | 58.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 437.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
FEMA-4809
CAS:1374760-95-8
FEMA-4809 activates TRPM8, the ion channel for cold sensation, and is used as a cooling …
Formula:
C17H17N3O2S
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
327.4
Ref: TM-T27308
| 1mg | 35.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 116.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 383.00 € | ||
| 200mg | 525.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
MSP3
CAS:1820968-63-5
MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective …
Formula:
C16H19NO3S
Purity:
99.46%
Color and Shape:
Solid
Molecular weight:
305.39
Ref: TM-T28118
| 2mg | 34.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 378.00 € | ||
| 200mg | 533.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
ABT 102
CAS:808756-71-0
ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.
Formula:
C21H24N4O
Purity:
98.38% - 99.72%
Color and Shape:
Solid
Molecular weight:
348.44
Ref: TM-T29522
| 1mg | 115.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 562.00 € | ||
| 50mg | 787.00 € | ||
| 100mg | 1,054.00 € | ||
| 200mg | 1,406.00 € | ||
| 1mL*10mM (DMSO) | 259.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
JYL 1421
CAS:401907-26-4
JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).
Formula:
C20H26FN3O2S2
Purity:
98.83%
Color and Shape:
Solid
Molecular weight:
423.57
Ref: TM-T15634
| 1mg | 70.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 612.00 € | ||
| 50mg | 938.00 € | ||
| 100mg | 1,491.00 € | ||
| 200mg | 1,985.00 € | ||
| 1mL*10mM (DMSO) | 173.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
TC-I 2014
CAS:1221349-53-6
TC-I 2014 shows antiallodynic properties in pain models.
Formula:
C23H19F6N3O
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
467.41
Ref: TM-T17006
| 1mg | 60.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 406.00 € | ||
| 50mg | 655.00 € | ||
| 100mg | 1,074.00 € | ||
| 200mg | 1,454.00 € | ||
| 1mL*10mM (DMSO) | 133.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
