TRP/TRPV Channel
TRP (Transient Receptor Potential) channels, including the TRPV subfamily, are a group of ion channels involved in various sensory processes, such as temperature sensation, pain perception, and osmoregulation. TRP channels are widely expressed in different tissues and play a role in physiological responses to environmental stimuli. The TRPV channels, in particular, are involved in detecting temperature changes and are implicated in conditions such as chronic pain, inflammation, and cancer. At CymitQuimica, we offer a comprehensive range of TRP/TRPV channel modulators to support your research in sensory biology, pain management, and signal transduction.
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IA-Alkyne
CAS:930800-38-7
IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.
Formula:
C8H12INO
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
265.09
Ref: TM-T15543
| 1mg | 59.00 € | ||
| 5mg | 123.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 322.00 € | ||
| 100mg | 444.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TRPV4 agonist-1 free base
CAS:2314467-59-7
TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 …
Formula:
C25H22F2N4O2
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
448.46
Ref: TM-T13214L
| 2mg | 41.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 285.00 € | ||
| 100mg | 395.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(Z)-Capsaicin
CAS:25775-90-0
(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic …
Formula:
C18H27NO3
Purity:
99.39% - 99.67%
Color and Shape:
Solid
Molecular weight:
305.41
Ref: TM-T1109
| 10mg | 52.00 € | ||
| 50mg | 152.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
GFB-8438
CAS:2304549-73-1
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM …
Formula:
C16H14ClF3N4O2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
386.76
Ref: TM-T11394
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 243.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
BI-749327
CAS:2361241-23-6
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 …
Formula:
C23H21F3N4O2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
442.43
Ref: TM-T10537
| 1mg | 130.00 € | ||
| 2mg | 177.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 425.00 € | ||
| 25mg | 626.00 € | ||
| 50mg | 819.00 € | ||
| 100mg | 1,094.00 € | ||
| 500mg | 2,188.00 € | ||
| 1mL*10mM (DMSO) | 300.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Resolvin D2
CAS:810668-37-2
Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative …
Formula:
C22H32O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
376.49
Ref: TM-T12707
| 10µg | 364.00 € | ||
| 25µg | 841.00 € | ||
| 50µg | 1,622.00 € | ||
| 100µg | 2,836.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
PF-04745637
CAS:1917294-46-2
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].
Formula:
C27H32ClF3N2O2
Purity:
97.91% - 99.3%
Color and Shape:
Solid
Molecular weight:
509
Ref: TM-T64337
| 1mg | 71.00 € | ||
| 5mg | 140.00 € | ||
| 10mg | 189.00 € | ||
| 25mg | 319.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 628.00 € | ||
| 200mg | 845.00 € | ||
| 1mL*10mM (DMSO) | 157.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
(S)-ABT 102
CAS:808756-70-9
N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.
Formula:
C21H24N4O
Purity:
99.41% - 99.78%
Color and Shape:
Soild
Molecular weight:
348.44
Ref: TM-T29522L
| 1mg | 78.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 476.00 € | ||
| 100mg | 649.00 € | ||
| 200mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
RN-1665
CAS:1803003-65-7
RN-1665 is a potent and selective TRPV4 receptor antagonist.
Formula:
C20H24F5N3O3S2
Purity:
100%
Color and Shape:
Soild
Molecular weight:
513.54
Ref: TM-T77723
| 1mg | 152.00 € | ||
| 5mg | 364.00 € | ||
| 10mg | 503.00 € | ||
| 25mg | 831.00 € | ||
| 50mg | 1,104.00 € | ||
| 100mg | 1,512.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
JC-229
CAS:3026716-22-0
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. …
Formula:
C20H14Cl4N2O3S
Purity:
97.14%
Color and Shape:
Liquid
Molecular weight:
504.21
Ref: TM-T77645
| 10mg | 43.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 90.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TRPM8 antagonist 3
CAS:2102179-29-1
TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).
Formula:
C13H12N2O4S
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
292.31
Ref: TM-T9709
| 1mg | 60.00 € | ||
| 5mg | 130.00 € | ||
| 10mg | 196.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 649.00 € | ||
| 200mg | 873.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
NGD-8243
CAS:573678-04-3
NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention
Formula:
C21H12F6N4
Purity:
90%
Color and Shape:
Solid
Molecular weight:
434.34
Ref: TM-T9818
| 1mg | 183.00 € | ||
| 5mg | 406.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,286.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Oleoyl Serotonin
CAS:1002100-44-8
Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.
Formula:
C28H44N2O2
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
440.66
Ref: TM-T22124
| 5mg | 64.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 309.00 € | ||
| 100mg | 536.00 € | ||
| 500mg | 1,170.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TRPA1-IN-2
CAS:2415206-22-1
TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 …
Formula:
C24H25F3N4O
Purity:
98.05%
Color and Shape:
Soild
Molecular weight:
442.48
Ref: TM-T77511
| 1mg | 124.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 461.00 € | ||
| 25mg | 784.00 € | ||
| 50mg | 1,095.00 € | ||
| 100mg | 1,475.00 € | ||
| 1mL*10mM (DMSO) | 337.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Vocacapsaicin hydrochloride
CAS:1931116-92-5
Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and …
Formula:
C26H42ClN3O4
Purity:
98.51% - 99.94%
Color and Shape:
Solid
Molecular weight:
496.08
Ref: TM-T39349
| 1mg | 375.00 € | ||
| 5mg | 915.00 € | ||
| 10mg | 1,217.00 € | ||
| 25mg | 1,839.00 € | ||
| 50mg | 2,471.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
AP 18
CAS:55224-94-7
AP-18 is a potent and selective TRPA1 inhibitor.
Formula:
C11H12ClNO
Purity:
90% - 99.85%
Color and Shape:
Solid
Molecular weight:
209.67
Ref: TM-T21543
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 72.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 211.00 € | ||
| 100mg | 331.00 € | ||
| 500mg | 709.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
Apcin A HCL
Apcin A HCL is an Apcin derivative. Apcin A HCL is an anaphase-promoting complex (APC) …
Formula:
C10H15Cl4N5O2
Purity:
99.30%
Color and Shape:
Solid
Molecular weight:
379.07
Ref: TM-T001
| 1mg | To inquire | ||
| 2mg | 63.00 € | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 200mg | To inquire | ||
| 500mg | 2,792.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
TRPM4 inhibitor 8
CAS:1353979-43-7
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to …
Formula:
C11H17BrN2
Purity:
97%
Color and Shape:
Liquid
Molecular weight:
257.17
Ref: TM-T9776
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 176.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 415.00 € | ||
| 500mg | 681.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 7 Jan 2025
JNJ-17203212
CAS:821768-06-3
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 …
Formula:
C17H15F6N5O
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
419.32
Ref: TM-T7526
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 133.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
Chembridge-5861528
CAS:332117-28-9
Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx …
Formula:
C19H23N5O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T2711
| 5mg | 40.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 168.00 € | ||
| 100mg | 253.00 € | ||
| 200mg | 362.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Monday 13 Jan 2025
