Potassium Channel
Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.
Found 294 products of "Potassium Channel"
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Guanosine 5'-diphosphate
CAS:Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
Formula:C10H15N5O11P2Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:443.2ML 297
CAS:ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively).Formula:C17H14F2N4OPurity:97.85%Color and Shape:SolidMolecular weight:328.32NS1643
CAS:NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.Formula:C15H10F6N2O3Purity:98.37% - 99.31%Color and Shape:SolidMolecular weight:380.24GAL-021
CAS:GAL-021 an intravenous BKCa-channel blocker.Formula:C11H22N6OPurity:97.71% - 99.66%Color and Shape:SolidMolecular weight:254.33Ref: TM-T3557
1mg34.00€5mg71.00€10mg98.00€25mg177.00€50mg268.00€100mg414.00€500mg888.00€1mL*10mM (DMSO)80.00€Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purity:98% - 99.96%Color and Shape:Light Yellow PowderMolecular weight:610.74NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Formula:C15H8F6N2O2Purity:97.66% - 98%Color and Shape:SolidMolecular weight:362.23GW9508
CAS:GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
Formula:C22H21NO3Purity:97.89% - 99.19%Color and Shape:SolidMolecular weight:347.41JNJ 303
CAS:JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).Formula:C21H29ClN2O4SPurity:99.28%Color and Shape:SolidMolecular weight:440.98Ref: TM-T7653
1mg48.00€2mg65.00€5mg89.00€10mg147.00€25mg325.00€50mg472.00€100mg705.00€1mL*10mM (DMSO)92.00€TRAM-34
CAS:TRAM-34 (Triarylmethane-34), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel, does not block cytochrome P450.
Formula:C22H17ClN2Purity:99.01% - 99.91%Color and Shape:SolidMolecular weight:344.84ML335
CAS:ML335 is a selective activator of TREK-1 and TREK-2.Formula:C15H14Cl2N2O3SPurity:99.73% - 99.79%Color and Shape:SolidMolecular weight:373.25Ref: TM-T4224
2mg40.00€5mg59.00€10mg89.00€25mg177.00€50mg268.00€100mg401.00€200mg580.00€1mL*10mM (DMSO)59.00€Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purity:97.79%Color and Shape:SolidMolecular weight:450.81Minoxidil sulfate
CAS:Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.Formula:C9H15N5O4SPurity:99.01% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:289.31ASP2905
CAS:ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene.Formula:C20H17FN8Purity:97.29% - 99.78%Color and Shape:SolidMolecular weight:388.4Ref: TM-T9070
1mg34.00€2mg46.00€5mg66.00€10mg90.00€25mg178.00€50mg295.00€100mg485.00€1mL*10mM (DMSO)73.00€AM-92016 hydrochloride
CAS:AM-92016 is a specific blocker of rectifier potassium current.Formula:C19H24Cl2N2O4S·HClPurity:98.68%Color and Shape:SolidMolecular weight:483.84Ref: TM-T5585
2mg35.00€5mg52.00€10mg96.00€25mg164.00€50mg279.00€100mg399.00€200mg567.00€1mL*10mM (DMSO)58.00€NS6180
CAS:NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
Formula:C16H12F3NOSPurity:99.83% - ≥95%Color and Shape:SolidMolecular weight:323.33Tetraethylammonium chloride
CAS:Tetraethylammonium chloride is a quaternary ammonium compound.Formula:C8H20ClNPurity:≥95%Color and Shape:White Solid Solid Particulate/PowderMolecular weight:165.7RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:392.47Ref: TM-T12786
1mg51.00€5mg144.00€10mg235.00€25mg399.00€50mg560.00€100mg787.00€200mg1,093.00€1mL*10mM (DMSO)125.00€Enflurane
CAS:Enflurane (Efrane), a volatile anaesthetic, inhibits Ca2+-activated K+ channels and is used to gauge anesthesia levels in gas chromatography.Formula:C3H2ClF5OPurity:99.64%Color and Shape:Clear Colorless Liquid Ordinary Temperature And Pressure Bp 56 8°C Density 1 50 G Cm-3 At Room Temperature Used As AnMolecular weight:184.49SCH-23390 hydrochloride
CAS:SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).Formula:C17H19Cl2NOPurity:98% - 99.83%Color and Shape:SolidMolecular weight:324.24Ref: TM-T4369
1mg39.00€2mg50.00€5mg78.00€10mg97.00€25mg195.00€50mg369.00€100mg550.00€1mL*10mM (DMSO)78.00€ICA-105574
CAS:ICA-105574 activates hERG, enhancing peak current and shortening action potential, while modulating activation kinetics.Formula:C19H14N2O4Purity:98.89%Color and Shape:SolidMolecular weight:334.33Ref: TM-T9009
1mg40.00€5mg87.00€10mg137.00€25mg281.00€50mg444.00€100mg650.00€200mg888.00€1mL*10mM (DMSO)96.00€Branaplam
CAS:Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
Formula:C22H27N5O2Purity:98.28% - 99.72%Color and Shape:SolidMolecular weight:393.48Rosuvastatin
CAS:Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.Formula:C22H28FN3O6SPurity:95.24% - 99.95%Color and Shape:SolidMolecular weight:481.54Levosimendan
CAS:Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.
Formula:C14H12N6OPurity:99.37% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28QO-40
CAS:QO-40 is a KCNQ2/3 potassium channels activator.Formula:C18H11ClF3N3OPurity:99.57%Color and Shape:SolidMolecular weight:377.75H3B-120
CAS:H3B-120: selective, competitive CPS1 inhibitor with anti-cancer properties. IC50: 1.5 μM, Ki: 1.4 μM.Formula:C19H24N4O2SPurity:99.03% - 99.2%Color and Shape:SolidMolecular weight:372.48Ref: TM-T11529
1mg38.00€2mg50.00€5mg80.00€10mg118.00€25mg250.00€50mg404.00€100mg647.00€200mg893.00€1mL*10mM (DMSO)88.00€CLP290
CAS:CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatricFormula:C19H21FN4O3SPurity:99.93% - >99.99%Color and Shape:SolidMolecular weight:404.46Ref: TM-T5444
1mg34.00€5mg73.00€10mg116.00€25mg190.00€50mg286.00€100mg430.00€200mg628.00€1mL*10mM (DMSO)62.00€BMS-191011
CAS:BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke modelsFormula:C16H10ClF3N2O3Purity:97.43%Color and Shape:SolidMolecular weight:370.71Tetrandrine
CAS:Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Cost-effective and quality-assured.Formula:C38H42N2O6Purity:99.61% - 99.94%Color and Shape:White SolidMolecular weight:622.75Doxapram
CAS:Doxapram (Dopram) is a respiratory stimulant that inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimer channels.Formula:C24H30N2O2Purity:99.42%Color and Shape:SolidMolecular weight:378.51BL-1249
CAS:BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).Formula:C17H17N5Purity:98% - 98.25%Color and Shape:SolidMolecular weight:291.35Ref: TM-T14666
1mg50.00€5mg105.00€10mg167.00€25mg245.00€50mg334.00€100mg587.00€500mg1,215.00€1mL*10mM (DMSO)146.00€VU590
CAS:VU590 is an inhibitor of extrarenal medullary potassium ROMK.VU590 inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.Formula:C24H32N4O7Purity:98.06%Color and Shape:SolidMolecular weight:488.53Eleclazine
CAS:Eleclazine (GS-6615) is a novel and selective voltage-gated sodium channel inhibitor with antiarrhythmic properties that reduces peak sodium current (INaP).Formula:C21H16F3N3O3Purity:98.67%Color and Shape:SolidMolecular weight:415.37Repaglinide D5
CAS:Repaglinide D5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for treatment type-2 diabetes mellitus.Formula:C27H36N2O4Purity:98%Color and Shape:SolidMolecular weight:457.62Dofetilide D4
CAS:Dofetilide D4 (UK 68789 D4), a deuterium-labeled version of Dofetilide, is categorized as a Class III antiarrhythmic medication.Formula:C19H27N3O5S2Purity:98%Color and Shape:SolidMolecular weight:445.59LY 303511
CAS:LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.Formula:C19H18N2O2Purity:98%Color and Shape:SolidMolecular weight:306.36Meclofenamic acid
CAS:Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.Formula:C14H11Cl2NO2Purity:99.98%Color and Shape:SolidMolecular weight:296.15CPK20
CAS:CPK20 is a potent and selective inhibitor of the KCNT1 channel, useful for epilepsy research.Formula:C23H24F6N2O2SColor and Shape:SolidMolecular weight:506.50TRAM 39
CAS:TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.Formula:C20H14ClNPurity:99.97%Color and Shape:SolidMolecular weight:303.78Ref: TM-T23471
1mg34.00€2mg47.00€5mg71.00€10mg102.00€25mg200.00€50mg318.00€100mg502.00€500mg1,063.00€CM-TPMF
CAS:CM-TPMF is a highly efficient and potent activator of the K(Ca)2.1 channel, Ser293 in the transmembrane segment 5, neurological disorders.Formula:C16H17ClN6O2Purity:99.94%Color and Shape:SolidMolecular weight:360.8B-TPMF
CAS:B-TPMF is a highly efficient and selective KCa2.1 channel inhibitor with an IC50 of 31 nM, interacting with serine residue at position 293 to inhibit KCa2.1.Formula:C19H24N6O2Purity:99.82%Color and Shape:SolidMolecular weight:368.43TWIK-1/TREK-1-IN-2
CAS:TWIK-1/TREK-1-IN-2 (Compound 2g) serves as an inhibitor of both TWIK-1 and TREK-1, targeting the TREK-1 homodimer and TWIK-1/TREK-1 heterodimer with IC50 valuesFormula:C20H29F3N2O2Purity:98%Color and Shape:SolidMolecular weight:386.45TWIK-1/TREK-1-IN-1
CAS:Compound 2a, identified as TWIK-1/TREK-1-IN-1, acts as an inhibitor of the TREK-1, a two-pore domain potassium channel (K2p) that forms TREK-1 homodimers andFormula:C21H24F3NO3Purity:98%Color and Shape:SolidMolecular weight:395.42RY796
CAS:RY796 is a selective voltage-gated potassium (KV2) channel inhibitor that inhibits KV2.1 and KV2.2, used in research on neurological disorders.Formula:C21H27N3O2Purity:98.59%Color and Shape:SolidMolecular weight:353.46Psora 4
CAS:Psora 4 (5-(4-Phenylbutoxy)psoralen) is a Kv1.3 blocker and a caloric restriction mimetic.Formula:C21H18O4Color and Shape:SolidMolecular weight:334.37ML402
CAS:ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.Formula:C14H14ClNO2SPurity:99.71%Color and Shape:SolidMolecular weight:295.78Ref: TM-T16109
5mg48.00€10mg75.00€25mg138.00€50mg215.00€100mg318.00€200mg444.00€1mL*10mM (DMSO)49.00€SCH-23390 maleate
CAS:SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM,Formula:C21H22ClNO5Purity:98%Color and Shape:SolidMolecular weight:403.86AVE-0118
CAS:AVE-0118 is a potassium channel blocker and suppresses persistent atrial fibrillation.Formula:C30H29N3O3Purity:97.04% - 98.93%Color and Shape:SolidMolecular weight:479.57Ref: TM-T26689
1mg70.00€5mg132.00€10mg173.00€25mg304.00€50mg449.00€100mg652.00€500mg1,369.00€1mL*10mM (DMSO)159.00€HN37
CAS:HN37, KCNQ2 activator (EC50=37 nM). Affordable Excellence: Reliable Quality You Can TrustFormula:C20H21FN2O2Purity:99.27%Color and Shape:SolidMolecular weight:340.39VU0405601
CAS:VU0405601 is a hERG channel activator that protects against drug-induced cardiac arrhythmias.Formula:C17H13BrN2O2Purity:99.16%Color and Shape:SolidMolecular weight:357.2Nifekalant hydrochloride
CAS:Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM.Formula:C19H28ClN5O5Purity:99.91%Color and Shape:SolidMolecular weight:441.91Vernakalant Hydrochloride
CAS:Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.Formula:C20H32ClNO4Purity:99.89%Color and Shape:SolidMolecular weight:385.93Ref: TM-T17227
1mg71.00€2mg92.00€5mg166.00€10mg260.00€25mg495.00€50mg713.00€100mg982.00€1mL*10mM (DMSO)170.00€Aprikalim
CAS:Aprikalim opens KATP channels, protects the heart, and at high doses, dilates blood vessels.Formula:C12H16N2OS2Purity:99.42% - 99.90%Color and Shape:SolidMolecular weight:268.4Pinacidil
CAS:Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure andFormula:C13H19N5Purity:99.9%Color and Shape:SolidMolecular weight:245.32UK 78282 hydrochloride
CAS:UK-78282 hydrochloride, a Kv1.3 blocker.UK-78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.Formula:C29H36ClNO2Purity:99.89%Color and Shape:SolidMolecular weight:466.05AVE1231
CAS:AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.Formula:C20H27N3O4SPurity:98.03%Color and Shape:SolidMolecular weight:405.51GAL-021 sulfate
CAS:GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.Formula:C11H24N6O5SPurity:99.92%Color and Shape:SolidMolecular weight:352.41Vernakalant
CAS:Vernakalant (RSD-1235) is a mixed ion channel blocker.Formula:C20H31NO4Purity:98%Color and Shape:SolidMolecular weight:349.46Almokalant
CAS:Almokalant: Class III antiarrhythmic, K+ channel blocker, inhibits Ikr current.Formula:C18H28N2O3SPurity:98%Color and Shape:SolidMolecular weight:352.49UK 66914
CAS:UK 66914 is a K(+) channel blocker for the study of cardiac arrhythmias.Formula:C18H24N4O3SPurity:99.75%Color and Shape:SolidMolecular weight:376.47SKA-111
CAS:SKA-111 activates KCa3.1 potassium channels, modulates membrane potential in endothelial cells, and dilates rat coronary arteries.Formula:C12H10N2SPurity:99.9%Color and Shape:SolidMolecular weight:214.29Ref: TM-T24799
1mg70.00€5mg153.00€10mg250.00€25mg504.00€50mg727.00€100mg1,017.00€500mg2,043.00€1mL*10mM (DMSO)167.00€KT-362 fumarate
CAS:KT-362 fumarate, a novel antagonist of Ca, K, and Na channels, induces vasodilation and relaxes rabbit arterial strips.
Formula:C26H32N2O7SPurity:99.75% - 99.98%Color and Shape:SolidMolecular weight:516.61MK-0448
CAS:MK-0448 is a novel and selective blocker of the Kv1.5 (KCNA5) channel, a key channel involved in cardiac repolarization current I Kur.Formula:C24H21FN4O2SPurity:99.25% - 99.79%Color and Shape:SolidMolecular weight:448.51DMP-543
CAS:DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters.Formula:C26H18F2N2OPurity:99.74%Color and Shape:SolidMolecular weight:412.43RL648_81
CAS:RL648_81 is a selective activator of KCNQ2/3 channels (EC50 = 190 nM). RL648_81 can be used in studies about neuronal hyperexcitability neurologic disorders.Formula:C17H17F4N3O2Purity:99.82%Color and Shape:SolidMolecular weight:371.33IKs124
CAS:IKs124 is a KCNE2/KCNQ1 potassium channel blocker, for hKCNE1 and hKCNE3, and can be used to study peptic ulcers.Formula:C18H26N2O3SPurity:99.53%Color and Shape:SolidMolecular weight:350.48CyPPA
CAS:CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.
Formula:C16H23N5Purity:99.88%Color and Shape:SolidMolecular weight:285.39XE991
CAS:XE991 is a Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1) and M-current and can be used in the study of neurological disorders.Formula:C26H20N2OPurity:98.87%Color and Shape:SolidMolecular weight:376.45GW 542573X
CAS:GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curveFormula:C19H28N2O5Purity:99.99%Color and Shape:SolidMolecular weight:364.44TWIK-1/TREK-1-IN-3
CAS:TWIK-1/TREK-1-IN-3 is a potassium channel TREK-1 inhibitor TWIK-1/TREK-1-IN-3 has antidepressant activity and can be used to study depression.Formula:C19H27F3N2O2Purity:99.04%Color and Shape:SolidMolecular weight:372.43ZTZ240
CAS:ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.
Formula:C12H8ClFN2OPurity:99.89%Color and Shape:SolidMolecular weight:250.66ZM 226600
CAS:ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity.Formula:C16H14F3NO4SPurity:99.87%Color and Shape:SolidMolecular weight:373.35Ref: TM-T23563
2mg34.00€5mg52.00€10mg75.00€25mg138.00€50mg215.00€100mg318.00€200mg444.00€1mL*10mM (DMSO)52.00€PD-118057
CAS:PD-118057, a potent hERG activator, may treat long QT syndrome and heart failure without hERG activity inhibition.Formula:C21H17Cl2NO2Purity:99.95% - 99.97%Color and Shape:SolidMolecular weight:386.27Ref: TM-T16444
1mg84.00€2mg107.00€5mg175.00€10mg263.00€25mg464.00€50mg692.00€100mg1,035.00€200mg1,396.00€1mL*10mM (DMSO)192.00€(+)-KCC2 blocker 1
CAS:(+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM).Formula:C22H25NO5SPurity:99.88%Color and Shape:SolidMolecular weight:415.5Ref: TM-T12504
1mg115.00€2mg172.00€5mg255.00€10mg374.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,147.00€1mL*10mM (DMSO)284.00€TASK-1-IN-1
CAS:TASK-1-IN-1: Potent, selective TASK-1 blocker (IC50: 148 nM), weaker on TASK-3 (IC50: 1750 nM), anticancer properties.
Formula:C22H20N2O2Purity:99.57%Color and Shape:SoildMolecular weight:344.41CLP257
CAS:CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.
Formula:C14H14FN3O2SPurity:99.5%Color and Shape:SolidMolecular weight:307.34Glibornuride
CAS:Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75).Formula:C18H26N2O4SPurity:98.94% - 99.5%Color and Shape:SolidMolecular weight:366.48Ref: TM-T15385
1mg71.00€5mg152.00€10mg236.00€25mg409.00€50mg580.00€100mg803.00€1mL*10mM (DMSO)167.00€Sigma-1 receptor antagonist 3
CAS:Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).Formula:C19H23ClFN3OPurity:99.95%Color and Shape:SolidMolecular weight:363.86Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Formula:C21H26N4O2Purity:99.54%Color and Shape:SolidMolecular weight:366.46Clobutinol hydrochloride
CAS:Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].Formula:C14H23Cl2NOPurity:98%Color and Shape:SolidMolecular weight:292.25DPO-1
CAS:DPO-1 可以高效抑制电压门控钾离子通道Kv1.5，也可以阻断超快速延迟整流钾电流。它能够预防房性心律失常。Formula:C22H29OPPurity:99.78%Color and Shape:SolidMolecular weight:340.44Ref: TM-T22745
5mg46.00€10mg71.00€25mg142.00€50mg205.00€100mg296.00€200mg414.00€1mL*10mM (DMSO)50.00€P-1075
CAS:P-1075 activates SUR2-KIR6 channels at 45 nM; may open mitoKATP channels and protect the heart.Formula:C12H17N5Purity:99.85%Color and Shape:SolidMolecular weight:231.3Ref: TM-T16420
1mg57.00€5mg119.00€10mg192.00€25mg349.00€50mg530.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)90.00€11-deoxy-PGF2a
CAS:11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contractionFormula:C20H34O4Color and Shape:SolidMolecular weight:338.48MCHR1 antagonist 2
CAS:MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG.Formula:C23H21FN2O5Purity:98.29%Color and Shape:SolidMolecular weight:424.42Ref: TM-T11966
2mg43.00€5mg66.00€10mg100.00€25mg210.00€50mg334.00€100mg537.00€200mg710.00€1mL*10mM (DMSO)80.00€VU0463271
CAS:VU0463271: KCC2 antagonist, IC50 61 nM, >100x selective over NKCC1, inactive on other GPCRs, channels, transporters.Formula:C19H18N4OS2Purity:97.84% - 99.55%Color and Shape:SolidMolecular weight:382.5Ref: TM-T17243
5mg48.00€10mg75.00€25mg152.00€50mg236.00€100mg350.00€200mg497.00€1mL*10mM (DMSO)To inquireKv3 modulator 1
CAS:Kv3 modulator 1 is a voltage-gated potassium channel Kv3 modulator that can be used to study neurologic-level diseases.Formula:C20H20N4O4Purity:99.41%Color and Shape:SolidMolecular weight:380.4C 101248
CAS:C 101248 (KCNK13-IN-1) is a selective and potent tandem pore halogen inhibitor of K+ channel 1 (THIK-1) inhibitor and a human and mouse KCNK13 inhibitor.Formula:C15H12N6OPurity:99.14% - 99.31%Color and Shape:SolidMolecular weight:292.3KV1.3-IN-2
CAS:KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.Formula:C16H23ClN2O4Color and Shape:SolidMolecular weight:342.818Opakalim
CAS:Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.Formula:C18H22F2N4OColor and Shape:SolidMolecular weight:348.39Kv7.2/Kv7.3 modulator-1
CAS:Kv7.2/Kv7.3 modulator-1 (compound 6a) acts as a modulator for Kv7.2/Kv7.3 channels, with a pEC50 value of 7.96 for opening these channels. Kv7.2/Kv7.3 modulator-1 is applicable in research related to epilepsy, depression, brain injury, and pain.Formula:C20H21F4N3O3Color and Shape:SolidMolecular weight:427.393KCC2 Modulator-2
CAS:KCC2 Modulator-2 (example 53) is a regulator of KCC2 with an EC50 of 0.215 μM. It is used in the research of neurological diseases.Formula:C35H45N5O3Color and Shape:SolidMolecular weight:583.76cis-KV1.3-IN-1
CAS:cis-KV1.3-IN-1, also known as Compound cis-18, is the cis-isomer of KV1.3-IN-1 and functions as an inhibitor of the KV1.3 channel. In Xenopus laevis oocytes expressing human hKV1.3, cis-KV1.3-IN-1 (10 μM) achieves an inhibition rate of 25.53% against KV1.3.Formula:C23H30N2O4SColor and Shape:SolidMolecular weight:430.56Kv7.2/Kv7.3 activator-1
CAS:Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.Formula:C19H22F2N4OColor and Shape:SolidMolecular weight:360.40Kv7.2/Kv7.3 agonist 1
CAS:Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.Formula:C14H14FN3O2Color and Shape:SolidMolecular weight:275.28Kv3 modulator 5
CAS:Kv3 modulator 5 (Example 5), a Kv3 channel modulator, enhances the Kv3.2 current and may be employed in research of hearing disorders [1].Formula:C20H20N4O4Color and Shape:SolidMolecular weight:380.4
