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Potassium Channel

Potassium Channel

Potassium channels are a diverse group of membrane proteins that facilitate the flow of potassium ions (K+) across the cell membrane. These channels play a crucial role in maintaining the resting membrane potential, regulating cell volume, and controlling the excitability of neurons and muscle cells. Potassium channels are involved in various physiological processes, including cardiac rhythm regulation, insulin secretion, and neurotransmitter release. Dysregulation of potassium channels is linked to conditions such as arrhythmias, epilepsy, and hypertension. At CymitQuimica, we offer a wide range of potassium channel modulators to support your research in electrophysiology, cardiovascular health, and neurobiology.

Found 277 products of "Potassium Channel"

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  • Agitoxin-2
    Targetmol
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    Agitoxin-2

    CAS:
    Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).
    Formula:C169H278N54O48S8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4090.87

    Ref: TM-TP2089

  • Apamin
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    Apamin

    CAS:
    <p>Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.</p>
    Formula:C79H131N31O24S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2027.34

    Ref: TM-TP1223

  • ShK-Dap22
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    ShK-Dap22

    CAS:
    Potent KV1.3 channel blocker; Kd 23 pM; selective; inhibits T cell activation; IC50 < 500 pM for mKV1.3.
    Formula:C166H268N54O48S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4012.7

    Ref: TM-TP2123

  • Iberiotoxin
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    Iberiotoxin

    CAS:
    <p>Selective blocker of the big conductance Ca2+-activated K+ channel.</p>
    Formula:C179H274N50O55S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4230

    Ref: TM-TP2014

  • Ebio2
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    Ebio2

    <p>Ebio2 is an effective activator of KCNQ2.</p>
    Formula:C17H19F2N3O2
    Color and Shape:Solid
    Molecular weight:335.349

    Ref: TM-T204914

  • Margatoxin
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    Margatoxin

    CAS:
    <p>KV1.3 channel blocker, IC50 36 pM, no effect on calcium-activated channels, hinders VEGF-induced Ca++ influx &amp; NO in endothelial cells.</p>
    Formula:C178H286N52O50S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4178.96

    Ref: TM-TP2004

  • Charybdotoxin
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    Charybdotoxin

    CAS:
    <p>Specific inhibitor of the big conductance Ca2+-activated K+ channel.</p>
    Formula:C176H277N57O55S7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4295.95

    Ref: TM-TP2059

  • MASP-2-IN-1
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    MASP-2-IN-1

    <p>MASP-2-IN-1 (Compound 77) is an inhibitor of mannan-binding lectin-associated serine proteases (MASP), specifically targeting MASP2 and MASP3, with IC50 values of 11.4 nM and 13.2 µM, respectively. It shows weak inhibitory activity on hERG with an IC50 of 175 µM. This compound exhibits poor stability in mouse plasma, with a half-life of 4.4 hours.</p>
    Formula:C22H21N7O3S
    Color and Shape:Solid
    Molecular weight:463.512

    Ref: TM-T204802

  • Cromakalim
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    Cromakalim

    CAS:
    <p>Cromakalim (BRL 34915) is an ATP-dependent K(+) channel opener, a smooth muscle relaxant with antiepileptic activity.</p>
    Formula:C16H18N2O3
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:286.33

    Ref: TM-T21478

  • KCNQ1 activator-1 
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    KCNQ1 activator-1 

    CAS:
    <p>N-[4-(4-Methoxyphenyl)-2-thiazolyl]-2-piperidinecarboxamide is a potent KCNQ1 activator for LQTS research.</p>
    Formula:C22H23N3O4S2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:457.57

    Ref: TM-T9778

  • Neosolaniol
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    Neosolaniol

    CAS:
    Neosolaniol, a type A trichothecene mycotoxin produced by Fusarium species, strongly induces an anorectic (loss of appetite) response.
    Formula:C19H26O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:382.4

    Ref: TM-T16285

  • Endoxifen Z-isomer hydrochloride
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    Endoxifen Z-isomer hydrochloride

    CAS:
    Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
    Formula:C25H28ClNO2
    Color and Shape:Solid
    Molecular weight:409.95

    Ref: TM-T6827

  • Nateglinide D5
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    Nateglinide D5

    CAS:
    <p>Nateglinide D5 is a deuterium labeled Nateglinide.</p>
    Formula:C19H27NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:322.45

    Ref: TM-T12178

  • Clamikalant sodium
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    Clamikalant sodium

    CAS:
    <p>Clamikalant sodium (HMR 1098) is an ATP-dependent potassium channel (KATP) cardiac-selective blocker, used in the study of arrhythmias.</p>
    Formula:C19H21ClN3NaO5S2
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:493.96

    Ref: TM-T63330

  • Flecainide
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    Flecainide

    CAS:
    <p>Flecainide is an orally administered antiarrhythmic agent acting as a sodium channel blocker and IKr inhibitor,PSVT.</p>
    Formula:C17H20F6N2O3
    Purity:99.896%
    Color and Shape:Solid
    Molecular weight:414.34

    Ref: TM-T21391

  • QO-58
    Targetmol
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    QO-58

    CAS:
    <p>QO-58 is a novel Kv7 activator (opener) that activates neuronal Kv7/KCNQ/M channels, danti-nociceptive effects on inflammatory pain</p>
    Formula:C18H8Cl2F4N4O
    Purity:99.17%
    Color and Shape:Solid
    Molecular weight:443.18

    Ref: TM-T28483

  • Almitrine mesylate
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    Almitrine mesylate

    CAS:
    <p>Almitrine mesylate targets Ca2+-dependent K+ channels in rat cells, used for chronic lung hypoxemia.</p>
    Formula:C28H37F2N7O6S2
    Purity:99.96%
    Color and Shape:Coa
    Molecular weight:669.76

    Ref: TM-T6978

  • TKIM
    Targetmol
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    TKIM

    CAS:
    <p>TKIM is a TWIK-related potassium channel 1 (TREK-1) inhibitor, binding to the pocket of the intermediate (IM) state of TREK-1.</p>
    Formula:C18H14ClN3O2S
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:371.84

    Ref: TM-T8700

  • Kv2-IN-A1
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    Kv2-IN-A1

    CAS:
    <p>Kv2-IN-A1 is an inhibitor of Kv2.1 and Kv2.2.</p>
    Formula:C20H17ClN4OS
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:396.89

    Ref: TM-T8977

  • E-4031 dihydrochloride
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    E-4031 dihydrochloride

    CAS:
    E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)
    Formula:C21H29Cl2N3O3S
    Purity:99.31% - 99.87%
    Color and Shape:Solid
    Molecular weight:474.44

    Ref: TM-T7198