CGRP Receptor
CGRP receptors are involved in the transmission of pain and the regulation of blood flow. CGRP is a neuropeptide that plays a critical role in migraine pathophysiology by dilating blood vessels and modulating pain signaling pathways. Targeting CGRP receptors has become a promising approach in the development of migraine therapies. At CymitQuimica, we offer a range of CGRP receptor modulators to support your research in pain management, neurobiology, and vascular health.
Found 55 products for "CGRP Receptor".
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Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Formula:C36H47ClN8O3Purity:98.93%Color and Shape:White SolidMolecular weight:675.3Calcitonin(salmon) Acetate(47931-85-1(free base))
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5Formula:C147H243N44O50S2Purity:99.29% - 99.63%Color and Shape:White SolidMolecular weight:3490.94HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.Formula:C141H234N44O40Purity:99.53%Color and Shape:SolidMolecular weight:3185.64Atogepant
CAS:Atogepant (MK-8031) is an orally available, selective and potent calcitonin gene-related peptide receptor (CGRP) antagonist for the study of migraine.Formula:C29H23F6N5O3Purity:99.66%Color and Shape:SolidMolecular weight:603.52Ref: TM-T26682
1mg147.00€5mg250.00€10mg313.00€1mL*10mM (DMSO)334.00€25mg620.00€50mg1,108.00€100mg1,611.00€200mg2,178.00€Eptinezumab
CAS:Eptinezumab is a humanised monoclonal antibody targeting CGRP (calcitonin gene-related peptide), which prevents CGRP binding to its receptor, migraine.Purity:95% - 96.9% (SDS-PAGE); 99.8% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:143.27 kDaFremanezumab
CAS:Fremanezumab (TEV-48125) is a humanised monoclonal antibody targeting CGRP, capable of neutralising human, mouse and rat CGRP, migraine.Purity:95% - 97.6% (SDS-PAGE); 95.9% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.49 kDaSB 268262
CAS:CGRP1 antagonistFormula:C18H15N3O4S2Purity:98%Color and Shape:SolidMolecular weight:401.46CGRP antagonist 1
CAS:CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for theFormula:C29H26N4O4Purity:99.55%Color and Shape:SolidMolecular weight:494.54Ubrogepant
CAS:Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formula:C29H26F3N5O3Purity:99.45% - 99.78%Color and Shape:Yellow SolidMolecular weight:549.54Ref: TM-T17194
1mg144.00€5mg358.00€1mL*10mM (DMSO)432.00€10mg565.00€25mg880.00€50mg1,161.00€100mg1,594.00€Rimegepant sulfate hydrate
CAS:Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.Formula:C56H64F4N12O13SColor and Shape:SolidMolecular weight:1221.2526CGRP antagonist 7
CAS:CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.Formula:C30H32FN5O3Color and Shape:SolidMolecular weight:529.61BI-44370
CAS:BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formula:C35H47N5O6Color and Shape:SolidMolecular weight:633.78HTL22562
CAS:HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formula:C40H49N11O5Color and Shape:SolidMolecular weight:763.904MK-3207 Hydrochloride
CAS:MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.Formula:C31H30ClF2N5O3Purity:98.19%Color and Shape:Yellow SolidMolecular weight:594.05DNA crosslinker 6
CAS:DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.Formula:C19H21N7OColor and Shape:SolidMolecular weight:363.42
