P-gp
P-glycoprotein is an ATP-dependent efflux pump that transports a wide variety of substrates, including drugs, toxins, and lipids, out of cells. It plays a critical role in drug resistance, particularly in cancer, by reducing the intracellular concentration of chemotherapeutic agents. P-gp is also involved in the blood-brain barrier, influencing the central nervous system's exposure to various compounds. At CymitQuimica, we provide a range of P-gp modulators to support your research in drug resistance, pharmacokinetics, and therapeutic development.
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HTT-D3
CAS:2254502-89-9
HTT-D3 is a Huntington splicing regulator that induces HTT mRNA degradation, leading to a reduction …
Formula:
C23H25FN6
Purity:
99.31%
Color and Shape:
Liquid
Molecular weight:
404.48
Ref: TM-T61991
| 1mg | 302.00 € | ||
| 5mg | 730.00 € | ||
| 10mg | 999.00 € | ||
| 25mg | 1,539.00 € |
Estimated delivery in United States, on Friday 2 May 2025
Tariquidar
CAS:206873-63-4
Tariquidar (XR9576)(Kd=5.1 nM) is a specific and effective non-competitive inhibitor of P-glycoprotein. It can reverse …
Formula:
C38H38N4O6
Purity:
98.07% - 99.17%
Color and Shape:
Solid
Molecular weight:
646.73
Ref: TM-T6287
| 5mg | 49.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 130.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 380.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Zosuquidar trihydrochloride
CAS:167465-36-3
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of …
Formula:
C32H31F2N3O2·3HCl
Purity:
100% - 99.55%
Color and Shape:
Solid
Molecular weight:
636.99
Ref: TM-T6018
| 1mg | 35.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 376.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Hypophyllanthin
CAS:33676-00-5
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
Formula:
C24H30O7
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
430.49
Ref: TM-TN1757
| 1mg | 52.00 € | ||
| 5mg | 137.00 € | ||
| 10mg | 216.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Zosuquidar
CAS:167354-41-8
Zosuquidar (RS 33295-198) is a potent P-glycoprotein inhibitor with antitumor activity that inhibits tumor growth.
Formula:
C32H31F2N3O2
Color and Shape:
Solid
Molecular weight:
527.6
Ref: TM-T6018L
| 25mg | 1,234.00 € | ||
| 50mg | 1,823.00 € | ||
| 100mg | 2,332.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Ceefourin 1
CAS:315702-40-0
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
Formula:
C11H10N4S3
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
294.42
Ref: TM-T8596
| 1mg | 43.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 389.00 € | ||
| 100mg | 550.00 € | ||
| 200mg | 785.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 5 May 2025
HM-30181 mesylate monohydrate
CAS:2097125-58-9
HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability …
Formula:
C39H42N6O11S
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
802.85
Ref: TM-T9173
| 1mg | 69.00 € | ||
| 2mg | 88.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 195.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 680.00 € | ||
| 200mg | 882.00 € | ||
| 500mg | 1,320.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Selamectin
CAS:220119-17-5
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and …
Formula:
C43H63NO11
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
769.96
Ref: TM-T4059
| 5mg | 37.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 105.00 € | ||
| 50mg | 170.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 378.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Paris saponin VII
CAS:68124-04-9
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
Formula:
C51H82O21
Purity:
99.51% - 99.63%
Color and Shape:
Solid
Molecular weight:
1031.18
Ref: TM-T4085
| 1mg | 50.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 304.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 647.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Chrysosplenetin
CAS:603-56-5
Chrysosplenetin is a metabolic inhibitor of artemisinin.
Formula:
C19H18O8
Purity:
97.43% - 98.53%
Color and Shape:
Solid
Molecular weight:
374.34
Ref: TM-TJS1159
| 1mg | 60.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 348.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 730.00 € | ||
| 500mg | 1,483.00 € | ||
| 1mL*10mM (DMSO) | 226.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Sinapine
CAS:18696-26-9
Sinapine: an alkaloid with chemo-resistance, antioxidant, and radioprotective properties from cruciferous seeds.
Formula:
C16H24NO5
Purity:
98% - 99.85%
Color and Shape:
White Or Light-Tan Solid
Molecular weight:
310.37
Ref: TM-T2S1200
| 5mg | 79.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 178.00 € | ||
| 50mg | 264.00 € | ||
| 100mg | 378.00 € | ||
| 500mg | 905.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Talinolol
CAS:57460-41-0
(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.
Formula:
C20H33N3O3
Purity:
98.80%
Color and Shape:
Solid
Molecular weight:
363.49
Ref: TM-T21640
| 1mg | 74.00 € | ||
| 2mg | 99.00 € | ||
| 5mg | 168.00 € | ||
| 10mg | 304.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 782.00 € | ||
| 100mg | 1,074.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Phellamurin
CAS:52589-11-4
Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.
Formula:
C26H30O11
Purity:
93.19%
Color and Shape:
Solid
Molecular weight:
518.51
Ref: TM-TN4761
| 1mg | 163.00 € | ||
| 5mg | 320.00 € | ||
| 10mg | 472.00 € | ||
| 25mg | 753.00 € | ||
| 50mg | 1,074.00 € | ||
| 100mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 410.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Convallatoxin
CAS:508-75-8
Convallatoxin is a natural product.
Formula:
C29H42O10
Purity:
99.27%
Color and Shape:
Prisms From Methanol + Ether Solid
Molecular weight:
550.64
Ref: TM-TN1525
| 1mg | 130.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 430.00 € | ||
| 25mg | 710.00 € | ||
| 50mg | 998.00 € | ||
| 1mL*10mM (DMSO) | 378.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Encequidar
CAS:849675-66-7
Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor.
Formula:
C38H36N6O7
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
688.73
Ref: TM-T8426
| 1mg | 48.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 246.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Voacamine
CAS:3371-85-5
Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.
Formula:
C43H52N4O5
Purity:
98.54%
Color and Shape:
Solid
Molecular weight:
704.9
Ref: TM-T2S0271
| 1mg | 126.00 € | ||
| 5mg | 264.00 € | ||
| 10mg | 449.00 € | ||
| 25mg | 722.00 € | ||
| 50mg | 938.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Trifluoperazine
CAS:117-89-5
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
Formula:
C21H24F3N3S
Purity:
98.3% - 99.46%
Color and Shape:
White To Yellowish Crystalline Powder
Molecular weight:
407.5
Ref: TM-T8389
| 1mg | 48.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 334.00 € | ||
| 100mg | 502.00 € | ||
| 500mg | 1,121.00 € |
Estimated delivery in United States, on Monday 5 May 2025
γ-Tocotrienol
CAS:14101-61-2
γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.
Formula:
C28H42O2
Purity:
97.27% - 98.13%
Color and Shape:
Solid
Molecular weight:
410.63
Ref: TM-T19768
| 1mg | 47.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Isosinensetin
CAS:17290-70-9
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.
Formula:
C20H20O7
Purity:
99.05% - ≥95%
Color and Shape:
Solid
Molecular weight:
372.37
Ref: TM-T2S0223
| 1mg | 66.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 344.00 € | ||
| 50mg | 512.00 € | ||
| 100mg | 740.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Polyoxyethylene stearate
CAS:9004-99-3
Polyoxyethylene stearate (POES) is an agent of non-ionic emulsifying.
Formula:
C20H40O3
Purity:
n~9-10
Color and Shape:
Light Amber Semisolid
Molecular weight:
328.29775
Ref: TM-T16561
| 5g | 49.00 € | ||
| 10g | 70.00 € |
Estimated delivery in United States, on Monday 5 May 2025
