P-gp
P-glycoprotein is an ATP-dependent efflux pump that transports a wide variety of substrates, including drugs, toxins, and lipids, out of cells. It plays a critical role in drug resistance, particularly in cancer, by reducing the intracellular concentration of chemotherapeutic agents. P-gp is also involved in the blood-brain barrier, influencing the central nervous system's exposure to various compounds. At CymitQuimica, we provide a range of P-gp modulators to support your research in drug resistance, pharmacokinetics, and therapeutic development.
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Sinapine thiocyanate
CAS:7431-77-8
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard …
Formula:
C16H24NO5·CNS
Purity:
98.19% - ≥95%
Color and Shape:
Solid
Molecular weight:
368.45
Ref: TM-T3392
| 10mg | 59.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 213.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
Solamargine
CAS:20311-51-7
Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.
Formula:
C45H73NO15
Purity:
99.17% - 99.88%
Color and Shape:
Solid
Molecular weight:
868.06
Ref: TM-T4034
| 1mg | 58.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 339.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
Elacridar
CAS:143664-11-3
Elacridar (GG918) is a potent inhibitor of P-glycoprotein and BCRP.Cost-effective and quality-assured.
Formula:
C34H33N3O5
Purity:
100% - 99.62%
Color and Shape:
Solid
Molecular weight:
563.64
Ref: TM-T2657
| 5mg | 41.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 464.00 € | ||
| 500mg | 736.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 19 Feb 2025
Verapamil
CAS:52-53-9
Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, …
Formula:
C27H38N2O4
Purity:
99.53%
Color and Shape:
Oil
Molecular weight:
454.6
Ref: TM-T20656
| 10mg | 35.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 72.00 € | ||
| 100mg | 99.00 € | ||
| 200mg | 142.00 € | ||
| 500mg | 226.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 19 Mar 2025
MCI826
CAS:140646-80-6
MCI826 is a potent and selective antagonist of P-glycoprotein (P-gp) and peptide leukotrienes (p-LTs), showing …
Formula:
C22H28N2O3S
Purity:
98.73%
Color and Shape:
Solid
Molecular weight:
400.53
Ref: TM-T16026
| 1mg | 650.00 € | ||
| 5mg | 1,672.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
P-gp inhibitor 1
CAS:2050747-49-2
P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 …
Formula:
C32H31N5O2
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
517.62
Ref: TM-T12341
| 5mg | 52.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 308.00 € | ||
| 200mg | 425.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
ONT-093
CAS:216227-54-2
ONT-093 (OC-144-093) is an oral P-glycoprotein (P-gp) inhibitor with potential anti-cancer activity, used in the …
Formula:
C32H38N4O
Color and Shape:
Liquid
Molecular weight:
494.67
Ref: TM-T63338
| 1mg | 51.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 135.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
coniferyl ferulate
CAS:63644-62-2
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis.
Formula:
C20H20O6
Purity:
97.09%
Color and Shape:
Solid
Molecular weight:
356.37
Ref: TM-T3S0012
| 1mg | 73.00 € | ||
| 5mg | 166.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 439.00 € | ||
| 50mg | 635.00 € | ||
| 100mg | 949.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
PGP-4008
CAS:365565-02-2
PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration …
Formula:
C26H23N3O
Purity:
98% - 98.53%
Color and Shape:
Solid
Molecular weight:
393.48
Ref: TM-T28396
| 1mg | 69.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 245.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 737.00 € | ||
| 100mg | 1,095.00 € | ||
| 500mg | 2,218.00 € |
Estimated delivery in United States, on Wednesday 2 Apr 2025
