P-gp
P-glycoprotein is an ATP-dependent efflux pump that transports a wide variety of substrates, including drugs, toxins, and lipids, out of cells. It plays a critical role in drug resistance, particularly in cancer, by reducing the intracellular concentration of chemotherapeutic agents. P-gp is also involved in the blood-brain barrier, influencing the central nervous system's exposure to various compounds. At CymitQuimica, we provide a range of P-gp modulators to support your research in drug resistance, pharmacokinetics, and therapeutic development.
Found 64 products for "P-gp".
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Hypophyllanthin
CAS:Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.Formula:C24H30O7Purity:98.39%Color and Shape:SolidMolecular weight:430.4908Zosuquidar
CAS:Zosuquidar (RS 33295-198) is a potent P-glycoprotein inhibitor with antitumor activity that inhibits tumor growth.Formula:C32H31F2N3O2Purity:99.59% - 99.99%Color and Shape:White SolidMolecular weight:527.6042HM-30181 mesylate monohydrate
CAS:HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs.Formula:C39H42N6O11SPurity:99.37%Color and Shape:SolidMolecular weight:802.849Encequidar
CAS:Encequidar (HM30181A) is a potent and selective P-glycoprotein inhibitor.Formula:C38H36N6O7Purity:98.72% - 99.93%Color and Shape:SolidMolecular weight:688.7284Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formula:C21H24F3N3SPurity:98.3% - 99.98%Color and Shape:SolidMolecular weight:407.496γ-Tocotrienol
CAS:γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.Formula:C28H42O2Purity:97.27% - 99.94%Color and Shape:SolidMolecular weight:410.6319Sinapine thiocyanate
CAS:Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds.Formula:C17H24N2O5SPurity:99.79% - ≥95%Color and Shape:SolidMolecular weight:368.448Solamargine
CAS:Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.Formula:C45H73NO15Purity:99.17% - 99.96%Color and Shape:SolidMolecular weight:868.0588Talinolol
CAS:(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.Formula:C20H33N3O3Purity:98.8%Color and Shape:SolidMolecular weight:363.4943Elacridar
CAS:Elacridar (GG918) is a potent inhibitor of P-glycoprotein and BCRP.Cost-effective and quality-assured.Formula:C34H33N3O5Purity:98.12% - >99.99%Color and Shape:SolidMolecular weight:563.64Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purity:97.43% - 98.4%Color and Shape:Yellow SolidMolecular weight:374.3414HTT-D3
CAS:HTT-D3 is a Huntington splicing regulator that induces HTT mRNA degradation, leading to a reduction in HTT protein levels.Formula:C23H25FN6Purity:99.78%Color and Shape:SolidMolecular weight:404.48Verapamil
CAS:Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Formula:C27H38N2O4Purity:99.61% - 99.96%Color and Shape:White OilMolecular weight:454.6016PGP-4008
CAS:PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.Formula:C26H23N3OPurity:97.41% - 97.99%Color and Shape:SolidMolecular weight:393.4803P-gp inhibitor 1
CAS:P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).Formula:C32H31N5O2Purity:98.16%Color and Shape:SolidMolecular weight:517.6208P-gp inhibitor 17
CAS:P-gp Inhibitor 17 (compound 2g), a potent inhibitor, directly interacts with the transmembrane domain of P-gp. This compound is useful for studying P-gp-mediated multidrug resistance in tumor cells [1].Formula:C36H49N3O3Color and Shape:SolidMolecular weight:571.79coniferyl ferulate
CAS:Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis.Formula:C20H20O6Purity:97.09% - 99.39%Color and Shape:White SolidMolecular weight:356.3692Reversin 121
CAS:Reversin 121 inhibits P-glycoprotein, boosts MDR1 ATPase, and combats cancer drug resistance.Formula:C34H47N3O9Molecular weight:641.75ONT-093
CAS:ONT-093 (OC-144-093) is an oral P-glycoprotein (P-gp) inhibitor with potential anti-cancer activity, used in the study of myelodysplastic syndromes.Formula:C32H38N4OPurity:98.86%Color and Shape:Yellow SolidMolecular weight:494.678-Prenylchrysin
CAS:8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.Formula:C20H18O4Color and Shape:SolidMolecular weight:322.354
