P-gp
P-glycoprotein is an ATP-dependent efflux pump that transports a wide variety of substrates, including drugs, toxins, and lipids, out of cells. It plays a critical role in drug resistance, particularly in cancer, by reducing the intracellular concentration of chemotherapeutic agents. P-gp is also involved in the blood-brain barrier, influencing the central nervous system's exposure to various compounds. At CymitQuimica, we provide a range of P-gp modulators to support your research in drug resistance, pharmacokinetics, and therapeutic development.
Found 55 products of "P-gp"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formula:C21H24F3N3SPurity:98.3% - 99.46%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:407.5γ-Tocotrienol
CAS:γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.Formula:C28H42O2Purity:97.27% - 98.13%Color and Shape:SolidMolecular weight:410.63Ref: TM-T19768
1mg44.00€2mg58.00€5mg96.00€10mg137.00€25mg224.00€50mg333.00€100mg489.00€200mg705.00€1mL*10mM (DMSO)92.00€Sinapine thiocyanate
CAS:Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds.Formula:C16H24NO5·CNSPurity:99.79% - ≥95%Color and Shape:SolidMolecular weight:368.45Talinolol
CAS:(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.Formula:C20H33N3O3Purity:98.8%Color and Shape:SolidMolecular weight:363.49Ref: TM-T21640
2mg34.00€5mg52.00€10mg92.00€25mg178.00€50mg313.00€100mg535.00€200mg775.00€1mL*10mM (DMSO)52.00€Elacridar
CAS:Elacridar (GG918) is a potent inhibitor of P-glycoprotein and BCRP.Cost-effective and quality-assured.Formula:C34H33N3O5Purity:98.12% - >99.99%Color and Shape:SolidMolecular weight:563.64Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purity:97.43% - 98.4%Color and Shape:SolidMolecular weight:374.34Ref: TM-TJS1159
1mg57.00€5mg120.00€10mg178.00€25mg329.00€50mg485.00€100mg692.00€500mg1,404.00€1mL*10mM (DMSO)215.00€HTT-D3
CAS:HTT-D3 is a Huntington splicing regulator that induces HTT mRNA degradation, leading to a reduction in HTT protein levels.
Formula:C23H25FN6Purity:99.31%Color and Shape:SolidMolecular weight:404.48Verapamil
CAS:Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Formula:C27H38N2O4Purity:99.61% - 99.93%Color and Shape:OilMolecular weight:454.6Ref: TM-T20656
10mg35.00€25mg51.00€50mg73.00€100mg96.00€200mg143.00€500mg230.00€1mL*10mM (DMSO)55.00€P-gp inhibitor 1
CAS:P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).Formula:C32H31N5O2Purity:98.65%Color and Shape:SolidMolecular weight:517.62Ref: TM-T12341
5mg50.00€10mg84.00€25mg150.00€50mg219.00€100mg304.00€200mg419.00€1mL*10mM (DMSO)58.00€P-gp inhibitor 17
CAS:P-gp Inhibitor 17 (compound 2g), a potent inhibitor, directly interacts with the transmembrane domain of P-gp. This compound is useful for studying P-gp-mediated multidrug resistance in tumor cells [1].Formula:C36H49N3O3Color and Shape:SolidMolecular weight:571.79ONT-093
CAS:ONT-093 (OC-144-093) is an oral P-glycoprotein (P-gp) inhibitor with potential anti-cancer activity, used in the study of myelodysplastic syndromes.Formula:C32H38N4OPurity:98.86%Color and Shape:SolidMolecular weight:494.67coniferyl ferulate
CAS:Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis.Formula:C20H20O6Purity:99.39%Color and Shape:SolidMolecular weight:356.37PGP-4008
CAS:PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.Formula:C26H23N3OPurity:97.41% - 97.99%Color and Shape:SolidMolecular weight:393.488-Prenylchrysin
CAS:8-Prenylchrysin is a C8-isopentenyl flavonoid compound. It acts as an inhibitor of P-glycoprotein (P-gp) and can be utilized in cancer research.Formula:C20H18O4Color and Shape:SolidMolecular weight:322.354NSC73306
CAS:NSC73306 is a thiosemicarbazone known for its role as a cell-permeable agent, exhibiting increased toxicity towards cells expressing p-glycoprotein.Formula:C16H14N4O2SColor and Shape:SolidMolecular weight:326.373
