PDE
Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.
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Olprinone
CAS:106730-54-5
Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation …
Formula:
C14H10N4O
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
250.26
Ref: TM-T5033
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 126.00 € | ||
| 100mg | 186.00 € | ||
| 200mg | 279.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
HA130
CAS:1229652-21-4
HA130 is a selective ATX (autotaxin) inhibitor.
Formula:
C24H19BFNO5S
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
463.29
Ref: TM-T2646
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 235.00 € | ||
| 100mg | 351.00 € | ||
| 200mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Mardepodect
CAS:898562-94-2
Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of …
Formula:
C25H20N4O
Purity:
98.82% - 99.81%
Color and Shape:
Solid
Molecular weight:
392.45
Ref: TM-T16499
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 148.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 358.00 € | ||
| 100mg | 536.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
BW-A 78U
CAS:101155-02-6
BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the …
Formula:
C13H12FN5
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
257.27
Ref: TM-T5101
| 1mg | 38.00 € | ||
| 5mg | 98.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 489.00 € | ||
| 200mg | 671.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Avanafil
CAS:330784-47-9
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as …
Formula:
C23H26ClN7O3
Purity:
98% - 99.66%
Color and Shape:
White Solid
Molecular weight:
483.95
Ref: TM-T2334
| 1g | 159.00 € | ||
| 200mg | 49.00 € | ||
| 500mg | 96.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Anagrelide hydrochloride
CAS:58579-51-4
Anagrelide hydrochloride (BL4162A) serves as a treatment for essential thrombocytosis.
Formula:
C10H7Cl2N3O·HCl
Purity:
99.77%
Color and Shape:
Off-White Powder
Molecular weight:
292.55
Ref: TM-T6390
| 5mg | 40.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 156.00 € | ||
| 100mg | 271.00 € | ||
| 200mg | 425.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
MBCQ
CAS:150450-53-6
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.
Formula:
C16H12ClN3O2
Purity:
99.45%
Color and Shape:
Solid
Molecular weight:
313.74
Ref: TM-T21965
| 5mg | 45.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 225.00 € | ||
| 100mg | 323.00 € | ||
| 200mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
HA 155
CAS:1229652-22-5
HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of …
Formula:
C24H19BFNO5S
Purity:
98.92%
Color and Shape:
Solid
Molecular weight:
463.29
Ref: TM-T22086
| 1mg | 36.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 303.00 € | ||
| 50mg | 453.00 € | ||
| 100mg | 638.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ibudilast
CAS:50847-11-5
Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an …
Formula:
C14H18N2O
Purity:
99.34% - 99.94%
Color and Shape:
White Solid
Molecular weight:
230.31
Ref: TM-T2137
| 10mg | 46.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 84.00 € | ||
| 200mg | 97.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
ML-030
CAS:1013750-77-0
ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with …
Formula:
C20H20N4O4S
Purity:
97.93%
Color and Shape:
Solid
Molecular weight:
412.46
Ref: TM-T5496
| 5mg | 39.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 189.00 € | ||
| 100mg | 273.00 € | ||
| 200mg | 397.00 € | ||
| 1mL*10mM (DMSO) | 44.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
SEP-0372814
CAS:1516895-53-6
SEP-0372814 is a potent inhibitor of PDE10.
Formula:
C21H19N7
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
369.42
Ref: TM-T8454
| 1mg | 85.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
YM976
CAS:191219-80-4
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)
Formula:
C17H16ClN3O
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
313.78
Ref: TM-T7954
| 5mg | 51.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Cilostamide
CAS:68550-75-4
Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 …
Formula:
C20H26N2O3
Purity:
≥95%
Color and Shape:
White To Off-White Solid
Molecular weight:
342.43
Ref: TM-T7642
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 257.00 € | ||
| 100mg | 386.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
D159687
CAS:1155877-97-6
D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the …
Formula:
C21H19ClN2O2
Purity:
97.57%
Color and Shape:
Solid
Molecular weight:
366.84
Ref: TM-T5474
| 5mg | 35.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 150.00 € | ||
| 100mg | 232.00 € | ||
| 200mg | 345.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
RS-25344 hydrochloride
CAS:152815-28-6
RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor
Formula:
C19H14ClN5O4
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
411.8
Ref: TM-T23256
| 2mg | 34.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 361.00 € | ||
| 200mg | 525.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
BRL-50481
CAS:433695-36-4
BRL-50481 is a novel and selective inhibitor of PDE7 with IC50s of 0.15, 12.1, 62 …
Formula:
C9H12N2O4S
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
244.27
Ref: TM-T5106
| 5mg | 55.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 211.00 € | ||
| 100mg | 355.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Piclamilast
CAS:144035-83-6
Piclamilast (RP 73401) is a PDE4 inhibitor.
Formula:
C18H18Cl2N2O3
Purity:
98.28%
Color and Shape:
Solid
Molecular weight:
381.25
Ref: TM-T23154
| 1mg | 52.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 305.00 € | ||
| 50mg | 491.00 € | ||
| 100mg | 699.00 € | ||
| 1mL*10mM (DMSO) | 109.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ensifentrine
CAS:1884461-72-6
Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 …
Formula:
C26H31N5O4
Purity:
98.45%
Color and Shape:
Solid
Molecular weight:
477.56
Ref: TM-T25376
| 1mg | 36.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 527.00 € | ||
| 100mg | 836.00 € | ||
| 200mg | 1,143.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Z-HA155
CAS:1312201-00-5
Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.
Formula:
C24H19BFNO5S
Purity:
98.28%
Color and Shape:
Solid
Molecular weight:
463.29
Ref: TM-T11533
| 1mg | 50.00 € | ||
| 2mg | 65.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 484.00 € | ||
| 100mg | 687.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Crisaborole
CAS:906673-24-3
Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.
Formula:
C14H10BNO3
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
251.05
Ref: TM-T4285
| 10mg | 45.00 € | ||
| 50mg | 54.00 € | ||
| 100mg | 90.00 € | ||
| 200mg | 107.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
