CymitQuimica logo
PDE

PDE

Phosphodiesterases (PDEs) are enzymes that hydrolyze cyclic nucleotides, such as cAMP and cGMP, into their inactive forms, playing a key role in regulating intracellular signaling pathways. PDE inhibitors are used in the treatment of various conditions, including cardiovascular diseases, erectile dysfunction, and respiratory disorders, due to their ability to modulate cyclic nucleotide levels. At CymitQuimica, we provide a range of PDE inhibitors to support your research in cell signaling, pharmacology, and therapeutic development.

Found 165 products of "PDE"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • Nortadalafil
    Targetmol
    + Info

    Nortadalafil

    CAS:
    <p>Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.</p>
    Formula:C21H17N3O4
    Purity:99.42%
    Color and Shape:Solid
    Molecular weight:375.38

    Ref: TM-T6147

  • Homo Sildenafil
    Targetmol
    + Info

    Homo Sildenafil

    CAS:
    <p>Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.</p>
    Formula:C23H32N6O4S
    Purity:99.88%
    Color and Shape:White Solid
    Molecular weight:488.6

    Ref: TM-T8919

  • GEBR-7b
    Targetmol
    + Info

    GEBR-7b

    CAS:
    <p>GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.</p>
    Formula:C13H16O3
    Purity:99.533%
    Color and Shape:Solid
    Molecular weight:220.26

    Ref: TM-T19865

  • Enoximone
    Targetmol
    + Info

    Enoximone

    CAS:
    <p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>
    Formula:C12H12N2O2S
    Purity:98.53%
    Color and Shape:Solid
    Molecular weight:248.3

    Ref: TM-T8462

  • MY-5445
    Targetmol
    + Info

    MY-5445

    CAS:
    <p>MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).</p>
    Formula:C20H14ClN3
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:331.8

    Ref: TM-T16164

  • Amino Tadalafil
    Targetmol
    + Info

    Amino Tadalafil

    CAS:
    <p>Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.</p>
    Formula:C21H18N4O4
    Purity:99.85%
    Color and Shape:White Powder
    Molecular weight:390.39

    Ref: TM-T7542

  • Sildenafil Mesylate
    Targetmol
    + Info

    Sildenafil Mesylate

    CAS:
    <p>Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.</p>
    Formula:C22H30N6O4S·xCH4O3S
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:570.68

    Ref: TM-T6983

  • Lodenafil
    Targetmol
    + Info

    Lodenafil

    CAS:
    <p>Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)</p>
    Formula:C23H32N6O5S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:504.6

    Ref: TM-T7346

  • [11C]MP 10
    Targetmol
    + Info

    [11C]MP 10

    CAS:
    <p>[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.</p>
    Formula:C25H20N4O
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:391.45

    Ref: TM-T6042

  • Osoresnontrine
    Targetmol
    + Info

    Osoresnontrine

    CAS:
    <p>Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.</p>
    Formula:C16H17N5O2
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:311.34

    Ref: TM-T8515

  • CP671305
    Targetmol
    + Info

    CP671305

    CAS:
    <p>CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.</p>
    Formula:C23H19FN2O7
    Purity:99.39%
    Color and Shape:Solid
    Molecular weight:454.4

    Ref: TM-T4695

  • Ziritaxestat
    Targetmol
    + Info

    Ziritaxestat

    CAS:
    <p>Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.</p>
    Formula:C30H33FN8O2S
    Purity:97% - 99.85%
    Color and Shape:Solid
    Molecular weight:588.7

    Ref: TM-T4041

  • PDE10-IN-1
    Targetmol
    + Info

    PDE10-IN-1

    CAS:
    <p>PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.</p>
    Formula:C21H19N7
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:369.42

    Ref: TM-T5411

  • RS-25344
    Targetmol
    + Info

    RS-25344

    CAS:
    <p>RS-25344: a strong PDE4 blocker, curbs eosinophil movement, boosts sperm motility in vitro.</p>
    Formula:C19H13N5O4
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:375.34

    Ref: TM-T9239

  • Lotamilast
    Targetmol
    + Info

    Lotamilast

    CAS:
    <p>Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.</p>
    Formula:C26H24N4O5
    Purity:97.03% - 99.29%
    Color and Shape:Solid
    Molecular weight:472.49

    Ref: TM-T3987

  • Enpp-1-IN-1
    Targetmol
    + Info

    Enpp-1-IN-1

    CAS:
    <p>Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)</p>
    Formula:C17H17N3O3S
    Purity:97.52%
    Color and Shape:Solid
    Molecular weight:343.4

    Ref: TM-T7888

  • GSK256066 Trifluoroacetate
    Targetmol
    + Info

    GSK256066 Trifluoroacetate

    CAS:
    <p>GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.</p>
    Formula:C29H27F3N4O7S
    Color and Shape:Solid
    Molecular weight:632.61

    Ref: TM-T11483

  • Crisaborole-d4
    Targetmol
    + Info

    Crisaborole-d4

    <p>Crisaborole-d4 (AN-2728-d4) is the deuterated form of Crisaborole. Crisaborole is a PDE4 inhibitor and also a cytokine release inhibitor.</p>
    Formula:C14H6D4BNO3
    Color and Shape:Solid
    Molecular weight:255.07

    Ref: TM-TMIJ-0249

  • ent-Tadalafil
    Targetmol
    + Info

    ent-Tadalafil

    CAS:
    <p>ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).</p>
    Formula:C22H19N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-T11206

  • Deltarasin
    Targetmol
    + Info

    Deltarasin

    CAS:
    <p>Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.</p>
    Formula:C40H37N5O
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:603.75

    Ref: TM-T6462